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K Ayas

Publications and source records attributed to K Ayas.

8 recordsLinked to original sources
PubMed1998

A comparison of procaine penicillin with sulbactam-ampicillin in the treatment of peritonsillar abscesses.

The clinical efficacy of procaine penicillin and sulbactam-ampicillin was compared in patients with peritonsillar abscesses after peroral abscess drainage. Forty-two patients were randomly assigned to receive either procaine penicillin or sulbactam-ampicillin intramuscularly on an outpatient basis. The mean time required for clinical symptoms (throat pain, dysphagia and fever) to resolve was compared. No statistically significant difference was found between the clinical recoveries of patients using either antibiotic (P > 0.05). The authors conclude that intramuscular procaine penicillin can be safely prescribed on an outpatient basis to most patients with peritonsillar abscess after incision and drainage. In contrast, a broader spectrum and more expensive antibiotic, such as sulbactam-ampicillin, should be reserved for non-responders.

Adult↗
PubMed1998

Laryngeal carcinoma and estrogen receptor analysis in patients after long-term follow-up.

Limitations in determining the progress and treatment of malignant diseases have prompted the investigation of new factors. Many molecules including estrogen receptors have been studied in an effort to understand the biological behavior of a tumor. To determine the effect of estrogen on laryngeal malignant cells, we analyzed the clinical findings of patients during long-term follow-up and compared these with the expression of estrogen receptors (ER). Fresh tissue samples from 30 patients with laryngeal carcinomas were analyzed for ER by a cytochemical method. Seven patients (23.3%) were found to be ER+. Advanced stages of the disease in patients with supraglottic tumors were found to be significantly ER-. While all patients were still alive for > or = 4 years in the ER+ group, two patients were dead due to primary tumor in the ER- group. Although the results of this study suggest that ER may play a role in determining the prognosis of disease in certain cases, further studies with larger series are needed before ER can be accepted as a prognostic marker.

Adult↗
PubMed1998

Prognostic significance of depth of invasion in cancer of the larynx.

To determine the prognostic significance of depth of invasion in laryngeal cancer, the depth of invasion of tumor was measured with an ocular micrometer on the laryngectomy specimens of 94 surgically treated patients with T1, T2, and T3 laryngeal cancer and was expressed in millimeters. There was a significant negative correlation between the depth of invasion and disease-free survival. The tumors with no clinical involvement of regional lymph nodes in neck (NO neck) had significantly less depth of invasion than those with involvement (N+ neck). The tumors with pathologically confirmed cervical lymph node metastasis had significantly more depth of invasion than those without metastasis. For tumors with a depth of invasion equal to or greater than 3.25 mm, the rate of cervical metastasis in this study has always been significantly higher than for those with a depth of invasion less than 3.25 mm (P < .05). The mean depths of invasion for cases with and without recurrence were not significantly different. According to the multivariate analysis, depth of invasion (P = .047) and patient age (P = .113) significantly affected the disease-free survival independently. The depth of invasion did not significantly affect the recurrence and the interval between surgery and the development of recurrence (P > .15). The depth of invasion should be measured in every laryngectomy specimen. The depth of invasion influences the cervical metastasis and disease-free survival significantly but does not affect the recurrence rate. The depth of invasion plays an independent role in determining the disease-free survival.

Adult↗
PubMed1994

Pleomorphic adenoma of the septum.

Pleomorphic adenoma, the most frequently seen tumour of the salivary glands, is extremely rare in the septum. In this publication a case of pleomorphic adenoma of the nasal septum is presented.

Adenoma, Pleomorphic↗
PubMed1993

Myxoma of the mandible.

Myxoma is a rare bone tumor of the jaws. The exact aetiology and pathogenesis of this tumor still remains obscure. The tumor is frequently seen in young adults and in the mandible. Enucleation or local curetting have been recommended in the literature as the treatments of choice, although some authors have suggested more radical procedures because of the recurrences. In this paper a case of myxoma of the mandible and a review of the literature is presented.

Child↗
PubMed1993

Giant osteoma of the frontal sinus.

Osteoma is the most common benign tumour of the nose and paranasal sinuses, and the frontal sinus is its most frequent location. This tumour may be discovered incidentally on radiographs, or may enlarge to produce symptoms and, rarely, complications referable to its location near the orbit and anterior cranial vault. A 61-year-old man presented with right proptosis was found to have a giant osteoma involving frontal sinus. The aetiology, presenting features, and treatment of this tumour are reviewed.

Frontal Sinus↗