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Biomedical subjects

K B DEOME

Publications and source records attributed to K B DEOME.

At least 19 recordsLinked to original sources

GROWTH OF MOUSE MAMMARY GLANDS IN VIVO AFTER MONOLAYER CULTURE.

Mouse mammary tissue grown in primary cell culture did not display specialized characteristics of the parent tissue. When implanted into gland-free mammary fat pads, not only did some of these cultured cells grow and produce normal mammary outgrowths, but some of the outgrowths formed glands which displayed a variety of culture-induced abnormalities.

Animals↗

Persistent vaginal cornification in mice.

Persistent vaginal cornification induced in A/Crgl mice by brief postnatal treatment with estrogen is not prevented by later ovariectomy, adrenalectomy, or hypophysectomy. Transplantation of the persistently cornified vaginae into ovariectomized normal mice or into ovariectomized persistently estrous mice also does not eliminate cornification in the majority of transplants. Administration of "anti-estrogenic" steroids temporarily alters the vaginal picture in some but not all of these mice. The vaginal epithelium of the persistently estrous mouse appears to represent an altered cell population which does not require estrogen for its constant keratinization.

Adrenalectomy↗