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Biomedical subjects

K B Desser

Publications and source records attributed to K B Desser.

At least 127 records · Page 7Linked to original sources
PubMed1975

Phasic left ventricular blood velocity alternans in man.

With the use of the Doppler ultrasonic flowmeter catheter, phasic instantaneous left ventricular blood flow velocity was measured by radiotelemetry in 28 subjects during pacemaker-evoked pulsus alternans. Blood velocity alternation was more manifest at faster pacing rates. Four patients demonstrated diastolic blood velocity alternans at the mitral valve. Discordant right heart pressure and left ventricular blood velocity alternation was recorded in three subjects. In one such patient, rate-related shifts of concordant and discordant left ventricular blood velocity alternans occurred. Intermediate or variant forms of alternation, comprising weak and strong beats in a ratio of 2:1, were noted in two subjects. This study provides the first comprehensive description of left ventricular blood velocity alternans in man. The observed phenomena may be related to an altered inotropic state or to beat to beat variations in end-diastolic fiber length.

Adolescent↗
PubMed1975

Advances in clinical vectorcardiography.

With use of the Frank lead system, still loop and timed vectorcardiograms were recorded in more than 5,000 patients sujected to complete right and left hear catheterization and selective coronary cine angiography. Data so obtianed demonstrated clincila superiority of the vectorcardiogram over the standard 12 lead scalar electrocardiogram. Specific advantages of the vectorcardiogram include (1) recognititin of undetected atrial and ventrcular hypertropy, (2) greater sensitivity in identification of myocardial infaraction, and (3) superior capability for diagnosis of multiple infaractions in the presnece of fascicular and burnany number of simultaneously recoreded electrocardiographic leadsfor the analysis of complex arrhythmias and beat to beat changes in intraventricula conduction. SINCE THE VALIDITY AND USEFULNESS OF THIS TECHNIQUE HAVE BEEN ESTABLISHED, IT SHOULD BECOME PART OF THE ROUTINE NONINVASIVE EVALUATION OF PATIENTS WITH CARDIOVASCULAR DISORDERS.

Adult↗
PubMed1975

Retinal vascular lesions in two patients with prolapsed mitral valve leaflets.

Two patients with retinal vascular lesions had mid-late systolic clicks on cardiac auscultation, suggesting the diagnosis of prolapsed mitral valve. The first patient demonstrated an inferonasal arteriolar branch occlusion secondary to embolization; the second patient had a central vein occlusion with multiple hemorrhages, glial proliferative tissue, and retinal neovascularization. This report describes the association between the prolapsed mitral valve syndrome and retinal vascular lesions.

Arterial Occlusive Diseases↗
PubMed1975

Effect of pacemaker-induced arrhythmias on coronary blood velocity in conscious man.

With the use of the Doppler ultrasonic catheter telemetry system, phasic left coronary blood velocity was measured in 34 conscious subjects during transvenous pacemaker insertion and right ventricular endocardial pacing. Ventricular premature depolarizations and ventricular tachycardia, occurring as consequences of pacing catheter manipulation and competitive rhythms, reduced peak coronary blood velocity by approximately one halft. These findings provide insight into the genesis of sudden death associated with pacemaker insertion, competitive or repetitive arrhythmias, and pacemaker "runaway."

Adult↗
PubMed1975

Right ventricular volume in congenital heart disease.

With use of the Frank lead system, still loop and timed vectorcardiograms were recorded in more than 5,000 patients subjected to complete right and left heart catheterization and selective coronary cineangiography. Data so obtained demonstrated clinical superiority of the vectorcardiogram over the standard 12 lead scalar electrocardiogram. Specific advantages of the vectorcardiogram include (1) recognition of undetected atrial and ventricular hypertrophy, (2) greater sensitivity in identification of myocardial infarction, and (3) superior capability for diagnosis of multiple infarctions in the presence of fascicular and bundle branch blocks. The timed biplane vectorcardiogram is as useful as any number of simultaneously recorded electrocardiographic leads for the analysis of complex arrhythmias and beat to beat changes in intraventricular conduction. Since the validity and usefulness of this technique have been established, it should become part of the routine noninvasive evaluation of patients with cardiovascular disorders.

Adolescent↗
PubMed1975

Blood velocity at mitral valve during atrial arrhythmias in man.

By means of the Doppler ultrasonic flowmeter catheter, phasic instantaneous left ventricular blood velocity was measured at the mitral valves of 184 conscious human subjects during atrial arrhythmias. Atrial extrasystoles and pacemaker-induced atrial tachycardias reduced peak mitral valve blood velocities in direct relation to shortened diastolic cycle length. Atrial fibrillation with irregular ventricular responses produced beat-to-beat alternations of peak mitral velocity, with smaller peak mitral blood velocities usually associated with shortened R-R intervals on the electrocardiogram. This report represents the first comprehensive description of instantaneous and continous phasic blood velocity at the mitral valve during atrial arrhythmias in man. It is concluded that atrial tachyarrhythmias exert an adverse influence on left ventricular filling velocities.

Adolescent↗