Biomedical subjects

K Bachmayer

Publications and source records attributed to K Bachmayer.

6 recordsLinked to original sources

PubMed1986

[What value do body weight, age and drug anamnesis have as an index of elevated digoxin level?].

A retrospective study of two groups of patients with a different plasma digoxin level (Group A: digoxin greater than or equal to 2 ng/ml, n = 32, Group B: digoxin less than 2 ng/ml, n = 34; total n = 66) showed a significantly lower creatinine clearance (p less than 0.05) in group A. This group also showed a weak correlation between the digoxin level and the length of observation (R = + 0.31, p less than 0.05, n = 29). Furthermore, a weak correlation between digoxin level and the ratio of average daily dosage to creatinine clearance was found for the total sample (R = + 0.30, p less than 0.05, n = 66). Patients treated for less than 7 days and with a higher digoxin level also had a higher dosage and worse renal function (p = 0.05, p = 0.01, respectively). A weak correlation also existed between the digoxin level and creatinine clearance and body weight for the whole sample (R = -0.29, p less than 0.05; R = -0.29, p less than 0.01, respectively; n = 66). The latter correlation was also found within each group. Apart from renal function, the medication taken and body weight seem to be useful variables in predicting impending elevation of the digoxin level. In this study these variables were found to be better suited for the said purpose than the ECG. These conclusions remain to be confirmed by means of a prospective study.

Acetyldigoxins↗

PubMed1986

[Is there a "hypertonic gallbladder" in hyperthyroidism? Initial results].

In five female patients with hyperthyroidism the motor function of the gallbladder was examined using sonography. After therapy, the fasting volume and the volume resulting 30 minutes after cholagogue showed a tendency to increase (p approximately 0.15, p approximately 0.25, respectively). The emptied volume and the rate of emptying showed no changes. Although our findings failed to attain statistical significance they suggest an influence on the motor function of the gallbladder resembling a "hypertonic gallbladder". It will be necessary to study a significantly greater number of patients to confirm this thesis.

Adult↗

PubMed1986

[Quantification of gallbladder kinetics in hypothyroidism using a simple sonographic method].

In 3 patients with hypothyroidism we tried to quantify the kinetics of the gallbladder using a simple sonographic method. The width of the gallbladder was found to be a good parameter for this purpose after we had found a good correlation between the relative decrease of the width with the relative decrease of the plane and the volume in a control group of 7 persons (R = 0.80, p less than 0.05, R = 0.85, p less than 0.05 respectively). After therapy, the speed of decrease of the width was 8-fold after cholagogue (p less than 0.05) and the increase of the shortening fraction was 13-fold (p less than 0.05). It was concluded that the width of the gallbladder in the examined group of patients reflects thyroid hormone application very sensitively. In view of the small number of patients this finding must be confirmed in a study involving a larger group of patients.

Adult↗

PubMed1986

[Evaluation of gallbladder kinetics using a very simple sonographic method].

Both cholecystographic and sonographic analysis of the contraction of the gallbladder showed good correlation between relative decrease of gallbladder width and relative decrease of the area or volume (R = 0.86, p less than 0.001, n = 14, R = 0.80, p less than 0.05, n = 7 respectively). Therefore, we used the relative decrease in the width of the gallbladder to predict the relative decrease in volume. The volume was calculated using a formula given in the literature, after determination of the length, width and depth, using realtime sonography. Correlation between the calculated relative decrease of volume of the gallbladder and the predicted value, was good (R = 0.90, p less than 0.01, n = 8). The relative decrease in the width of the gallbladder in the with of the gallbladder! Can therefore represent the Contraction of the whole gallbladder. Due to its simple method of determination it can be recommended as a complement to sonography of the gallbladder. First of all, however, it will be necessary to conduct a study in a relatively large number of healthy volunteers to obtain the reference values.

Adult↗

PubMed1986

[Sonography of 2 unusual extramedullary plasmacytomas].

The author describes two unusual extramedullary plasmacytomas. In the first patient, a 48-year old man, a mass was found sonographically in a retroperitoneal space. A discontinuity of the left iliac bone bordering on the tumour was prominent. Two years earlier, an epidural plasmacytoma had been removed. Subsequently, multiple osteolysis also developed in the left iliac bone. It was concluded that after destruction of the compact bone the plasmacytoma had infiltrated directly into the retroperitoneal space. An excretion of light chains of the kappa type was found in the urine. Six months after the tumour in the left iliac fossa had been confirmed, a second mass was seen in the abdomen. The patient died a few days later. Autopsy revealed plasmocytic infiltration of the retroperitoneal lymph nodes. In the second case, a man of 29 years of age, multiple tumours developed in the skin after removal of a meningeal plasmacytoma. Two months later, a recurrent intracranial tumour and a tumour in the left sinus maxillaris were found. Sonography of the "skin tumours" revealed intramuscular location and a cyst-like aspect; their consistency, however, was considerably increased. Histologically, plasmacytoma was present. Paraproteinaemia IgA of the kappa type was found. No lesions of the bone were seen. 11 months after the diagnosis of an intracranial tumour the patient died from local recurrence of the disease.

Adult↗

PubMed1985

[Chronic periduodenitis as a sonographic mass in the region of the pancreas head].

A 47 year-old male presented with increased stool frequency, abdominal discomfort and weight loss. Two sonographers found independently a "mass" in the region of the head of the pancreas. 8 years before the patient had had a Billroth-II-surgery. Laparatomy revealed a chronic periduodenitis as sonographic substratum. Therefore, basing on sporadic reports, an anamnestic finding of a Billroth-II-surgery should be kept in mind in differential diagnosis of a tumor of the head of the pancreas when employing sonography as a diagnostic tool.

Chronic Disease↗