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Biomedical subjects

K Bandhauer

Publications and source records attributed to K Bandhauer.

At least 19 recordsLinked to original sources
PubMed1992

Testicular dysplasia causing disturbance of spermiogenesis in patients with unilateral torsion of the testis.

Fifty-five patients were followed up for their state of fertility at a time varying in length after testicular torsion. In addition to the spermiogram they were screened for sperm antibodies. Biopsy samples were collected from the contralateral (not contorted) testis in 34 patients at the time of torsion or immediately afterwards. Two to 8 years after torsion only 7 out of 55 patients had a normal spermiogram. Nineteen had an OAT syndrome, 10 had asthenospermia and 19 had teratospermia. Sperm antibodies occurred very rarely at the time of torsion (2/36) or at the time of a further checkup (2/36). Immunological damage to the noncontorted testis by the contorted one seems therefore rather unlikely. Histology of the contralateral testis, the samples of which were taken at the time of torsion (30) or up to 4 months later (4), showed pathological conditions in 30/34 cases (desquamation of the germinative epithelium, atrophy of the Leydig cells, malformation of spermatoblasts) and normal spermiogenesis in 4 cases only. Hence, a preexistent congenital testicular dysplasia must be assumed to be the cause of the observed disturbance of spermiogenesis and reduced fertility.

Adult↗
PubMed1992

[One-stage urethra repair with end-to-end anastomosis].

The direct anastomosis in one session is the method of choice for the treatment of urethral strictures (< 2.5 cm length) when at least three internal urethrotomies have failed. If certain important details are kept in mind about the operative technique (wide anastomosis without tension), suitable suture materials used, and the urinary diversion is done without placing a burden on the anastomosis, the long-term results are good. The direct anastomosis and operative approach can be varied according to the special situation in individual cases. The analysis of 47 patients operated on with direct anastomosis for strictures in the posterior urethra (28 post-traumatic, 9 iatrogenic, 10 postinflammatory) revealed that 83% of the patients had good or satisfactory results, while in 8 patients (17%) the results were poor. The poorist long-term results occurred in post-traumatic strictures in the bulbomembranous part of the urethra connected with complicated pelvic fractures.

Anastomosis, Surgical↗
PubMed1992

[Surgical refertilization following vasectomy--an increasing need].

Surgical refertilization by vaso-vasostomy, taking place a long time after vasectomy, gains increasing importance in men whose partnership condition has changed since the time of sterilization. Apart from the surgical technique, the length of time between vasectomy and vaso-vasostomy, the age of the patient and immunological factors are of importance for the success of the vaso-vasostomy, that is the procreation of sound children. From the view of the surgical technique the single-layered anastomosis without splinting, carried out with magnifying glasses, produces satisfactory results comparable to those of more complicated techniques (operation microscope). The success rate of recanalization is between 80 and 95%. However, the rate of refertilization (ejaculation of fertile sperms) is between 50 and 70% only. Firstly, this discrepancy is based on the space of time between vasectomy and vaso-vasostomy. If the vasectomy has taken place more than ten years ago, the prognosis is significantly poorer. Secondly, it is based on the occurrence of circulating sperm antibodies after vasectomy. This rare immunological phenomenon, which is based on a disturbed resorption of sperms, reduces the fertility considerably. Thirdly, the age of the patient is of importance. If the patient is more than 50 years old at the time of surgery, the fertility is significantly reduced, as the spermatogenesis deteriorates in this age group under normal conditions as well. In spite of these reservations the surgical refertilization after vasectomy by means of vasovasostomy is a promising method, that can be recommended to the patient concerned.

Adult↗
PubMed1991

[Therapy of urologic complications in 210 consecutive kidney transplantations].

The results of 210 consecutive renal transplant operations between 1969 and 1989 were assessed with respect to urological complications. 17 patients had urological problems. 4.7% of the patients had ureteric complications (obstruction or leakage). 2.8% of this series showed other general urological complications like bladder bleeding, extravasation at the ureterovesical anastomosis and bladder leakage. One patient had interstitial cystitis and an anastomosis of the transplant ureter with an ileal conduit was performed. Ureteric complications were managed in all cases by revisional surgery, excision of the affected segment followed by ureteroneocystostomy or uretero-/pyeloureterostomy. Bladder bleeding and extravasation at the ureterovesical anastomosis were treated by transurethral and percutaneous drainage procedures. Open surgery was necessary for great bladder leakage. In all cases the function of the transplant kidney could be maintained.

Follow-Up Studies↗
PubMed1990

[BEP-chemotherapy in patients with testicular tumors--is it worthwhile?].

Since 1985 44 consecutive patients with testicular cancer have been treated with a modified BEP regimen. 70% had metastatic disease and 30% received adjuvant therapy. After mean follow-up of 26 (8-56) months, 91% of patients are alive and all are in remission. Chemotherapy-related side effects were alopecia (100%), myelosuppression (100%), nausea/vomiting (89%) and fever (66%). Patients reported nausea has been rare. It is concluded that BEP chemotherapy is a highly effective treatment which secures complete remission or cure even in patients with advanced metastatic disease. In retrospect the patients considered the treatment worthwhile despite the stress involved.

Adult↗
PubMed1990

[Injuries of the urogenital system].

Ultrasonography is accepted as a valuable screening method for the detection of renal trauma, although it does not make any functional contribution. Computerized tomography has replaced excretory urography for the evaluation of blunt renal trauma, because it makes more precise diagnosis possible. Arteriography is mandatory when injuries of the renal branch are suspected. The management of renal trauma should restore normal circulation and renal function and should preserve as much functioning renal tissue as possible. For renal contusion and minor cortical lacerations, even when there is a small extravasation of urine, conservative management is sufficient, while major cortical lacerations and injuries of the renal vessels require prompt operative methods. The classification of urethral ruptures is based on rectal palpation of the prostate, distribution and size of hematomas and urethrography. A primary catheter for diagnostic purposes is strictly contraindicated. Urinary diversion proximal to the urethral lesion is the primary therapeutic procedure, while the definite management of the ruptured urethra can be postponed. Injuries to the organs of the urogenital system are rarely life threatening, and in the case of multiple trauma their management can be adapted to fit in with the treatment of injuries to other vital organs. Nevertheless, diagnosis and adequate treatment of injured urogenital organs must not be neglected as long-lasting or permanent damage could result.

Angiography↗
PubMed1989

[Percutaneous occlusion therapy of idiopathic varicocele as an alternative to operation].

Percutaneous sclerotherapy of varicocele is performed at the Kantonsspital of St. Gallen since 1983 as an alternative to the conventional operation. The main indication to treat varicocele was an associated fertility disorder. Success rate was around 60%. Adverse reactions of the treatment occurred in only 6.5%. The procedure can be done on an outpatient basis, is well tolerated by patients, economic and is associated with only minimal complications.

Adult↗
PubMed1979

Histological grading of prostatic carcinoma and its clinical evaluation.

The clinical control of patients with T1--T3, N0--M0 prostatic carcinomas allows us to draw the following conclusions regarding the grading. (1) The grading of the primary tumor is of great help in establishing the prognosis. (2) The results of the various applied treatments, like radical prostatectomy, radiation, and heterosexual hormone therapy, depend on the primary grade. The use of cytostatics in badly or undifferentiated prostatic carcinomas deserves on the contrary, better attention. (3) The changing of the grading at the various check-ups is of great therapeutical significance.

Follow-Up Studies↗
PubMed1979

[Kidney calculi and medullary neoplasms].

Even though we do not find confirmed among our patients the high percentage of 25% of kidneys with medullary carcinoma in lithogenetic patients - this is certainly connected with the fact that our patients are in no way selected - we nevertheless are of the opinion that this picture of a disease should more considered and because of the danger of progression the possibilities of a preventive therapy which are at present at our disposal should increasedly be used.

Adult↗
PubMed1977

Combined mesterolon-clomiphene citrate therapy for treatment of oligospermia.

42 subfertile patients with normal levels of plasma testerone (26 subnormal, suffering from oligospermia) have been treated with a combination of clomiphene citrate (50 mg Clomid daily) and mesterolon (50 mg Proviron daily) over a period of at least 3-6 months. The treatment resulted in pregnancy in 6 cases and in a significant improvement of the sperm count in 16. In 7, however, whilst the sperm count improved the qualitative results were unsatisfactory as many sperms were immature. Restricted spermatogenesis and a sperm count below 5 million/ml must be considered unfavourable but does not constitute a counter-indication to the combined therapy. No hazardous complications were observed.

Cell Count↗
PubMed1977

Analysis of bladder configuration and pressure from pressoreceptor stimulation in rabbits.

In a previous study (Bödeker, J., Vogt, W., Kölln, C.-P., and Nagel, R.: Invest. Urol., 12: 461, 1975.) pressoreceptor stimulation induced micturition at less than normal bladder filling. Furthermore, urethral pressure profile decreased in both maximal and mean values. In the present investigation the effects of pressoreceptor stimulation on bladder configuration, intravesical pressure, and vesicoureteral reflux were studied. With pressoreceptor stimulation, the bladder outlet became more funnel-shaped; the change in bladder configuration occurred without alteration in intravesical pressure; and vesicoureteral reflux could not be demonstrated.

Animals↗