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K Bartmann

Publications and source records attributed to K Bartmann.

52 records · Page 3Linked to original sources
PubMedDate not supplied

Bacteriological and biochemical criteria for the diagnosis of bacterial infections in chronic obstructive pulmonary disease (COPD).

In a prospective study the quantitated culture of washed sputum, the number of leukocytes and the concentration of albumin and fibrinogen in sputum were compared as diagnostic parameters for bacterial infections in patients with chronic obstructive pulmonary disease. No single criterium and no combination of criteria showed satisfactory specificity and sensitivity. Two reasons were established for the relatively loose correlation between the parameters: 1) they follow a different time course and 2) the biochemical and cellular signs of inflammation have a certain non-specificity with regard to bacterial infections. They also depend on the underlying disease. The selection of optimal criteria will become feasible only after the dynamics of bacterial and other inflammations of the respiratory tract have been studied in detail.

Albumins↗
PubMedDate not supplied

[N-formimidoyl-thienamycin: in vitro activity in bacteria with resistance to beta-lactam antibiotics or gentamicin].

The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of N-formimidoyl-thienamycin were determined for 25 strains each of Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Serratia marcescens and Pseudomonas aeruginosa which were resistant to gentamicin and/or acylureido penicillins or cefotaxime, cefoperazone or moxalactam, and for 38 strains of the group D streptococci. The drug was very active against the most frequently encountered gram-negative resistant causative organisms of nosocomial infections. The MIC ranged from 0.25-1 mg/l for multiresistant Enterobacteriaceae, and from 0.5-4 mg/l for multiresistant P. aeruginosa. The group D streptococci (enterococci) showed a low MIC (median: 0.75 mg/l); the median of the MBC was greater than 64 mg/l, however.

Anti-Bacterial Agents↗