PubMed Health⌕ Search

Biomedical subjects

K Benli

Publications and source records attributed to K Benli.

At least 19 recordsLinked to original sources
PubMed1997

Secondary multiple intracranial hydatid cysts caused by intracerebral embolism of cardiac echinococcosis: an exceptional case of hydatidosis. Case report.

The authors present an extremely rare case of secondary multiple cerebral echinococcosis caused by presumed intracerebral and arterial embolism of cardiac hydatidosis in a 7-year-old girl. The first manifestations were symptoms of raised intracranial pressure. Unfortunately, before the primary ruptured echinococcosis cyst was detected in the myocardium of the left ventricle, the patient underwent nine operations over an 8-year period for hydatid embolism affecting the brain and the femoral artery and was treated with concurrent mebendazole therapy. The combined therapy would not have been successful without removal of the intracardiac hydatid cyst. This case is unusual because of the multiplicity of intracranial hydatid cysts and its embolic origin from cardiac echinococcosis. The present case is believed to be the first one in which the development of an embolism in the brain was studied by magnetic resonance imaging.

Brain Diseases↗
PubMed1996

Microsurgical removal of a free segment of microcatheter in the anterior circulation as a complication of embolization.

Endovascular therapy for cerebral arteriovenous malformations, although generally accepted to be a safe procedure, is not without risks. We present a patient with a 20 cm free segment of a catheter in the anterior circulation as a complication of embolization. This is a very rare complication. To our knowledge, only six cases have been reported in the literature. We believe this to be the first reported case of this complication treated surgically via craniotomy and arteriotomy.

Adult↗
PubMed1996

Twenty-five years experience in the treatment of trigeminal neuralgia. Comparison of three different operative procedures in forty-nine patients.

A series of 49 patients with trigeminal neuralgia (TN) were treated by three different surgical procedures: (1) peripheral ablative procedures in 10 patients; (2) percutaneous rhizotomy in 17 patients and (3) intracranial rhizotomy (IR) in 22 patients. On the basis of surgical treatment, the concept that neurovascular compression is a mechanical factor in the aetiology of TN was supported in 14 to 18 patients who underwent posterior fossa exploration. The results support the conclusion that retromastoid craniectomy with IR is the procedure of choice for the majority of patients with TN.

Adult↗
PubMed1996

Factors affecting morbidity and mortality following surgical intervention in patients with intracranial meningioma.

BACKGROUND: Meningiomas usually grow slowly but they may cause recurrences despite surgical resection. The impact of clinical, neuroradiological and surgical characteristics on operative morbidity and mortality of patients operated on for intracranial meningioma was analysed. METHODS: A series of 450 patients operated on for intracranial meningiomas at the Department of Neurosurgery, Hacettepe University Hospital during the period 1964-1992 is reported. The surgical results were analysed with regard to intracranial site, extent of removal, histological type, and different time periods. Computed tomography (CT) and magnetic resonance imaging (MRI) facilitated the diagnosis and helped with the planning of treatment. RESULTS: Two hundred and ninety-two patients were examined with both CT and MRI. Overall mortality was 4% but showed a decline from 9% in the pre-CT era to 3% in the post-CT era and to 1% in the past 3 years. CONCLUSIONS: Operative mortality and recurrence rates are affected by the intracranial location of the tumour, histological type, and extent of tumour removal. Emphasis is also given to the importance of the introduction of the imaging techniques, and the microsurgical techniques with the Cavitron ultrasonic surgical aspirator (CUSA), laser, and/or bipolar coagulator which have further improved the operative mortality and recurrence rates.

Adolescent↗
PubMed1995

Impairment of motor coordination in mice after ingestion of aluminum chloride.

The mechanisms of aluminum (Al) neurotoxicity is of increasing interest. Al compounds are known to produce neurological and behavioral abnormalities in some mammalian species. The present study was designed to determine the effects of Al chloride on the skilled motor performance in mice on the rota-rod treadmill. Al chloride, depending on the duration of treatment, produced an impairment of the motor coordination ability in mice.

Aluminum↗
PubMed1995

Congenital nasal encephalocele: a review of 35 cases.

Congenital encephaloceles are rare lesions which are usually seen in the occipital region, in the West. They may rarely be seen in the frontal region and they have distinct diagnostic features, together with several other pathological conditions occurring in this region. In order to emphasize these points, a retrospective analysis of 35 cases which have been operated on in our clinic, is made in this study. The findings are compared with the data obtained from the literature.

Bone Transplantation↗
PubMed1995

Solitary dural plasmacytoma: case report.

Solitary intracranial plasmacytomas are exceedingly rare. Before this case report, only 14 cases of solitary dural and 4 cases of intracerebral plasmacytomas had been reported in the literature. We present a case of solitary plasmacytoma originating from the right frontal dura mater in a 52-year-old man; we also review the literature on the previous cases. To our knowledge, our patient is the first patient with a solitary dural plasmacytoma to be examined with magnetic resonance imaging.

Dura Mater↗
PubMed1993

Reaction of rabbit lateral periventricular tissue to non-infected and infected (Staphylococcus epidermidis) shunt tubing implants. A light and transmission electron microscope study.

The reactions of periventricular tissue of the lateral ventricle to non-infected and infected (Staphylococcus Epidermidis) silicone shunt tubing were examined by light and transmission electron microscopy. It was shown that reactive changes occurred in periventricular tissue in response to the implant of sterile shunt tubing. On the other hand in infected implanted silicone shunt tubing, proliferation of inflammatory cells within the ventricle and periventricular tissue, loss of integrity of the ependyma, glial cell proliferation, and excessive extracellular oedema were demonstrated. Proliferation of ependymal cells combined with inflammatory responses may be a factor in the pathogenesis of infected shunt obstruction.

Animals↗
PubMed1993

Efficacy of ampicillin/sulbactam combination in experimental shunt infections caused by Staphylococcus epidermidis. A light and scanning electron microscope study.

In this study, the efficacy of ampicillin/sulbactam combination in reactions of periventricular tissue of the lateral ventricle induced by the presence of infected (Staphylococcus epidermidis) silicone rubber shunt tubing was examined by using light and scanning electron microscopy. It was demonstrated that reactive changes to implants had occurred in periventricular tissue in the control group. In infected shunt tubing without given prophylactic antibiotic group, generalized meningitis and ventriculitis, loss of integrity of ependymal cells, numerous inflammatory cells, bacterial colonies, exuda and even pus were seen. It was also shown that rarely inflammatory reactions, minimal disintegration of ependymal cells, no bacterial colonies, and phagocytes were present in the group which was given prophylactic ampicillin/sulbactam combination per and postoperatively. We think that ampicillin/sulbactam combination is very effective in prevention and treatment of shunt infections.

Ampicillin↗
PubMed1993

Primary spinal extradural hydatid disease: report of a case with magnetic resonance characteristics and pathological correlation.

A rare case of hydatid disease of the lumbar extradural area and of the paravertebral muscles is reported. The patient underwent surgery, resulting in complete recovery. The limitations of computed tomography and the benefits of magnetic resonance imaging in forming a diagnosis are discussed. Magnetic resonance has been found to be an invaluable tool, not only in detecting the soft tissue extent of the disease but also in delineating the viability of hydatid cysts.

Combined Modality Therapy↗
PubMed1991

Pontine hematoma. A report of three surgically treated cases.

Untreated pontine hematoma is always fatal, while surgical evacuation is effective and safe. After surgical intervention, immediate improvement and full or nearly full recovery may be observed. In this report, three successfully removed pontine hematomas are presented. The cause of this pathological entity, surgical interventions and their results are discussed and cases reported in the literature are reviewed.

Adolescent↗
PubMed1991

The role of lipid peroxidation in the genesis of vasospasm secondary to subarachnoid hemorrhage.

The aim of this study is to find out the possible trigger role of lipid peroxidation in vasospasm. Haemoglobin-free washed erythrocyte membranes (erythrocyte ghost) corresponding to 2.5 mg membrane protein was mixed with 0.5 umol NADPH 3 umol ADP, 4 umol ferrous sulphate and injected into the cisterna magna of cats to stimulate lipid peroxidation in vivo (Group 1). The second group was injected lml/kg whole blood and the control group 1 ml/kg saline. Angiographic studies revealed significant vasospasm in five cats in group 1. Severe vasospasm was seen in six cats in group 2. A significant increase in lipid peroxidation was observed in groups 1 and 2, compared to the control group. These results may suggest that free radical products may play an important role in the complex genesis of vasospasm in subarachnoid haemorrhage.

Angiography↗
PubMed1990

Giant congenital meningioma in a newborn.

The authors report the case of a giant meningioma in a 5-day-old newborn. Congenital meningiomas are extremely rare. Five newborns with meningiomas have been reported in the literature to date. This is the first case of a newborn with a giant meningioma with supra- and infratentorial and intraorbital components.

Brain Neoplasms↗
PubMed1990

Malignant teratoma of the cerebellopontine angle: case report.

A case of malignant teratoma of the cerebellopontine angle is presented. Preoperative findings suggested an acoustic neurinoma or a meningioma. Particularly in adulthood, malignant teratomas arising in unusual locations can simulate common intracranial tumors.

Adult↗
PubMed1990

Papillary carcinoma of the sphenoid sinus associated with sphenoid sinus abscess presenting as cavernous sinus syndrome. A case report.

Primary carcinoma of the sphenoid sinus is a rare tumor that may present with dramatic neuro-ophthalmological-symptoms and signs of which spheno-cavernous syndrome is the best known clinical entity. The most frequently encountered histological types of the sphenoid carcinomas are squamous cell carcinoma and papillary carcinoma, in decreasing order of frequency. In this article, a papillary carcinoma of the sphenoid sinus associated with sphenoid sinus abscess is presented. We are not aware of previously reported papillary carcinoma of the sphenoid sinus associated with sphenoid sinus abscess presenting as a cavernous sinus syndrome.

Abscess↗
PubMed1988

Examination of autologous and embryonic cortical brain tissue transplantation to adult brain cortex in rats.

Autologous and embryonic cortical brain tissue was transplanted to adult rats in order to reconstruct experimentally degenerated cortical brain tissue. Rats were decapitated within 6 or 12 weeks. Viability of the graft tissues was studied by light and electron microscopy. Embryonic cortical brain tissue grafts became enlarged but adult cortical brain tissue grafts were found to be unaltered. Electron-microscopically observed mitochondria and other cell organellae and the newly vascularized areas clearly showed that the graft tissues were alive.

Animals↗
PubMed1988

Fetal pituitary transplants into the hypothalamic area of hypophysectomized rats.

The pituitary tissue, when transplanted to extracerebral sites other than the normal anatomic position, fails to perform its secretory function properly. Several works on experimental intracerebral pituitary transplantation have shown that the transplanted tissue has been able to survive histologically. In this study, fetal pituitary tissue was implanted into the anterior hypothalamic area of the hypophysectomized rat by stereotactic methods. Electron-microscopic examination and hormonal blood levels demonstrated that ectopic pituitary tissue was able to survive to establish the correct anatomic relationship and thus perform secretory functions when transplanted intracerebrally.

Animals↗