Monte Carlo test of the Flory-Huggins theory for polymer mixtures.
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Biomedical subjects
Publications and source records attributed to K Binder.
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In 30 sterility patients with normal course of the cycle, 17 OHP already rises significantly one day before the LH-peak. It influences not only progesterone and E2 but also hypothalamic opiate activity and LHRH and LH secretion. 17 OHP is on the one hand discussed as a further trigger for the LH peak and is on the other hand regarded as an initiator for incipient luteinization.
Recent research indicates that opioid peptides may be participants in the coordination and control of the menstrual cycle. The peripheral ovarian steroids (progesterone and estradiol) seem to modulate endogenous opioid activity and thereby hypothalamic LH-RH-secretion. This mechanism works during the luteal-phase under the influence of progesterone. The purpose of this study is to investigate the interaction of endogenous opioid peptides and peripheral ovarian steroids in 24 women by comparing progesterone and beta-endorphin levels of unstimulated and HMG-stimulated cycles. The women with stimulated cycles showed significantly higher progesterone and beta-endorphin levels. The interaction of progesterone und beta-endorphin may partly be explained by the fact that progesterone acts on progesterone receptors in the central nervous system. This leads to activity of opioid neurons in the brain and finally influences LH-RH- and LH-release. Beta-endorphin production is also discussed to come from the ovary. Beta-endorphin is involved maintaining normal luteal phase and therefore plays an important role in reproduction.
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A case of anterior cleavage syndrome in a 27-year-old female patient is described. It is remarkable for the unusual completeness and prominence of the symptoms. In addition to medodermal anomalies of the anterior segment (e.g., prominent ring of Schwalbe, posterior embryotoxon, peripheral anterior synechiae, hypoplasia of the iris stroma) the case also manifested microcornea, cataract, glaucoma, excessive myopia, partial anodontia vera with maxillary hypoplasia and telecanthus. It is the first time that Rieger's syndrome has been described in association with endocrine orbitopathy, caused by hyperthyroidism with isolated elevation of T3 in the blood serum and a soft struma. Possible genetic correlations and the role of the secondary glaucoma in the two syndromes are discussed.
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A mechanism of psychological repression is invoked to explain the unsatisfactory results of current forms of health education. We are not conscious of the multiplicity of dangers which constantly surround us, including dangers to our health, which also fall victim to this repression. Particularly powerful motivation is required to overcome this situation. In an experiment, communications which aroused excessive fear resulted in much more effective repression than less frightening one. Particular attention must therefore be devoted to the intensity of fear arousal. Potentially promising ways of motivating individual age groups are presented. Attention is drawn to error frequently observed. Treatment of the recumbent child must be avoided until a firm psychic relationship exists between the child and the dentist, as everything that "comes from above' appears threatening to the child. Much more psychological knowledge should be imparted not only to doctors and dentists but also to teachers and parents.
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