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Biomedical subjects

K Boda

Publications and source records attributed to K Boda.

At least 109 records · Page 6Linked to original sources
PubMed1977

[Consumption of drinking water by workers in a steel foundry during working hours in Hungary].

In a former paper the authors had investigated the fluorine intake per kilogram body weight and its extreme possibilities. This study includes 97 workers of a steel foundry. The amount of liquid ingested during working hours was measured, for 30 persons in summer during 90 days and 67 persons in winter during 201 days. Inside and outside temperatures were recorded. The mean age was 40,02 years. The mean intake of drinking water was, in summer 3732 ml (+/- s 1176 and +/- sx 123 ml) and in winter 1835 ml (+/- s 684 and +/- sx 48 ml). The mean value was 2422 ml and the extreme values were 500 and 8500 ml. The calculation of the individual mean values showed however, that the water intake follows an irregular pattern of distribution. About 11% consumed more than 41, and about 2% more than 51 per day continuously. In this study, there are those who consume habitually little, more and a lot of drinking water. With the results, the authors are examining the possibilities of the maximum fluorine intake.

Adult↗
PubMed1977

Spatial interactions of blood pressure reflexes.

Spatial interactions of depressor and pressor reflexes evoked by unilateral and bilateral stimulation of various and somatic afferents were analysed in chloralase-pentobarbital or pentobarbital anaesthetized cats. It has beed found that the dynamics of the spatial interactions can be described by regression equations as a function of the size of the responses evoked by separate stimulation. The angle of inclination and the position of the regression line in the coordinate systems is influenced by the type of reflex, the anaesthetic used and the functional state of the animal. At standard conditions the relations are reproducible. Sagittal splitting of the medulla and the pons did not essentially alter the character of the interaction. The forms of the interactions were unaffected by previous stimulations.

Afferent Pathways↗
PubMed1976

[Gains in body composition and total fat content in mice after administration of aurothioglucose with a limited amount of animal feed].

We investigated the effect of a single application of aurothioglucose on the weight and fat content of mice in the case of a limited feed quantity. In the experiment we used 41 mice -- females of the "H" strain, of which 14 served as controls and 27 were experimental mice to which we applied aurothioglucose in the dose of 1 mg g-1 of liveweight, i. p. We found that, under the conditions of feeding a limited quantity of feeds, there occurs in the animals that had been injected with aurothioglucose a statistically significant increase of the weight gains and of the total quantity of fat compared with the control animals.

Adipose Tissue↗
PubMedDate not supplied

Vasopressin deficiency decreases the frequency of gastroduodenal ulceration in humans.

Vasopressin is a stress hormone released from the posterior pituitary. In humans suffering from central diabetes insipidus, this release of vasopressin is diminished. It was shown previously that the congenitally vasopressin-deficient Brattleboro homozygous rat is less sensitive to various ulcerogenic stimuli. In this study, we investigated the incidence of gastroduodenal ulceration in vasopressin deficient patients. Data on patients aged 20-70, hospitalized in Hungary between 1992 and 1995 were compared with those on the total population in this age group (6,681,020 in 1994). Subjects with central diabetes insipidus were selected separately (815 cases). Gastroduodenal ulceration was compared in subjects with an intact vasopressin release and vasopressin-deficient patients. The frequencies of gastroduodenal ulceration were also examined separately in male and female subjects. In the total population, the frequency of gastroduodenal ulceration was lower in vasopressin-deficient cases (2.22% versus 0.61%; P < 0.005). Among normal-vasopressin subjects, males have a higher risk of gastroduodenal ulceration than females (3.04% versus 1.46%, respectively; P < 0.001). Among vasopressin-deficient subjects, a similar male:female ratio was observed, but it was not significant (P = 0.36). In comparison to the normal-vasopressin population, the incidence of gastroduodenal ulceration was reduced among vasopressin-deficient males and females by 77% (P < 0.01) and by 82% (P < 0.05), respectively. In conclusion, endogenous vasopressin has a significant harmful action towards the human gastroduodenal mucosa. Peptide and non-peptide vasopressin receptor antagonists might have a potential therapeutic benefit in the treatment (as an adjuvant) and prevention of gastroduodenal ulceration.

Adult↗