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Biomedical subjects

K Boyle

Publications and source records attributed to K Boyle.

14 recordsLinked to original sources

Post-hospitalization concerns of medical-surgical patients.

In response to the phenomenon of earlier-than-ever discharge, the post-hospitalization concerns of medical-surgical patients were investigated in a descriptive survey conducted in physicians' offices and clinics. The 150 recently discharged patients typically identified multiple concerns including understanding their progress, activity, insurance, medications, and pain control. Differences were found in number of concerns according to age, gender, length of hospital stay, type of treatment (medical or surgical), and perceived presence or absence of discharge planning.

Adult

Out of the darkness: group cognitive therapy for depressed elderly.

1. Depression affects an estimated 50% of the population over age 65. With the current expansion of the elderly in this country, the problem will continue to increase. 2. Depressed individuals view situations negatively when more positive interpretations are equally valid. The thrust of cognitive therapy is to replace the faulty and negative perceptions with more valid and positive ones. 3. Cognitive therapy was found to be effective in the elderly. Residents attended sessions regularly, and the change in the depression level for group participants was highly significant statistically and clinically noticeable.

Aged

Nutritional assessment of the elderly.

1. The elderly often have a declining ability to absorb and utilize nutrients, and they frequently take medications that interfere with the body's use of nutrients. 2. Nutritional assessment involves history taking (medical, social, and psychological) and physical examination with physical measurements and analysis of laboratory data. 3. The most frequently used indicators of nutritional risk or depletion are those obtained by nurses in direct contact with patients. 4. Nurses tended to rely more on intuitive data than on laboratory values, upper arm circumference, or skinfold thickness.

Aged

Evaluation of the acute hemodynamic effects and pharmacokinetics of coronary thrombolysis produced by intravenous tissue-type plasminogen activator in the anesthetized dog.

The thrombolytic dose-response effectiveness and pharmacokinetics of tissue-type plasminogen activator (rt-PA) was evaluated in anesthetized, open-chest dogs instrumented for the measurement of systemic hemodynamics. Intracoronary thrombi were formed by injecting thrombin (100 U) and CaCl2 (50 microM) into a cannulated, isolated segment of the left anterior descending coronary artery (LAD). Coronary blood flow was measured by placing an electromagnetic flow probe proximal to the LAD thrombus. Thirty minutes after formation of a stable LAD thrombus, intravenous infusion of rt-PA was given at rates of 0.5, 1, 2, 4, or 8 micrograms/kg/min (n = 8/dose) for 60-90 min, and the animals were followed for an additional 30 min. In vehicle-treated animals, residual thrombus wet weight, determined at the end of the experiment, was 30 +/- 4 mg (mean +/- SEM, n = 8) and spontaneous reperfusion did not occur. The rt-PA produced a dose-related increase in the number of animals reperfusing, a decrease in the time to reperfusion, and a decrease in residual thrombus weight, but had no effect on systemic hemodynamics. The increase in infusion rate from 0.5 to 4 micrograms/kg/min resulted in a linear increase in both the steady-state rt-PA plasma concentration and the area under the rt-PA plasma concentration versus time curve (n = 3-5 animals/dose); between the infusion rates of 4 and 8 microgram/kg/min there was a disproportionate increase in both these parameters that was due to a decrease in the total systemic clearance of rt-PA. The postdosing elimination half-life (t1/2 alpha) did not differ significantly at any dose of rt-PA, and the pooled half-life (t1/2 alpha) for all doses of rt-PA was 2.36 +/- 0.12 min (n = 19).(ABSTRACT TRUNCATED AT 250 WORDS)

Anesthesia

Sociological aspects of attenders and non-attenders of antenatal classes.

One hundred and eighty-six women delivering in a one-month period were questioned about their attendance at antenatal education classes and various sociological characteristics. Forty-three women had never attended antenatal classes: young women, unmarried women, Maori or Pacific Island women and women of low socio-economic status or educational achievement were disproportionately represented amongst the non-attenders. Non-attenders of antenatal classes also lacked knowledge about the classes and had more transport and child care problems when compared with attenders. The present antenatal classes are not being attended by those who would probably benefit most from education for parenthood.

Adult

Increasing women's compliance with opportunistic cervical cancer screening: a randomized trial.

Our objective was to evaluate the efficacy and acceptability of two interventions designed to increase opportunistic cervical cancer screening. We designed a randomized trial of two interventions additional to usual care. We recruited 17 male general practitioners selected at random from the inner metropolitan region of Sydney, Australia. The patients were 202 women, between 20 and 65 years of age, eligible for a Pap smear. We allocated minimal and maximal interactional interventions to obtain consent for a Pap smear. Our main outcome measure was women's having a Pap smear during the consultation or within one month. We also measured acceptability of interventions to practitioners and women. These were our results: minimal: 55% of women had a Pap smear; maximal: 67% of women had a Pap smear; total when both approaches are combined: 61%. We conclude that brief advice is as effective as maximal persuasion in increasing women's compliance with opportunistic screening in routine consultations. Both interventions were acceptable to women. Practitioners preferred the minimal intervention. We demonstrate opportunistic screening is an effective and acceptable way to encourage women at risk to have a Pap smear.

Adult