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K Bregulla

Publications and source records attributed to K Bregulla.

At least 19 recordsLinked to original sources
PubMed1978

[A contribution to the problem of heterologous insemination (author's transl)].

The problem of a heterologous insemination must occasionally be dealt with. The conditions for such treatment are not good in the Federal Republic of Germany. This, however, should not negatively influence the quality of the therapy. At least the serologic characteristics of the donor should be known. The impetus for this article was provided by the unsuccessful course of a pregnancy after heterologous insemination in a patient with an established, severe Rhesus incompatibility.

Blood Group Antigens↗
PubMed1977

[Results of in vitro sperm penetration tests in cervical mucus under takings of the sequential oral contraceptive ovanon and sequilar (author's transl)].

The in vitro penetrability of cervical mucus by sperm was investigated in women who were taking Ovanon or Sequilar. Measurements were made under constant experimental conditions on every day of the cycle. The depth of penetration differed strikingly between women with normal menstrual cycles and women taking the sequential hormonal contraceptives. The penetration depth was substantially less when Sequilar or Ovanon was used. The Sequilar induced cervical sperm barrier during the entire cycle was almost as strong as that observed when combined preparations are used. During the proliferative phase of the cycle the penetration depth allowed by Ovanon was less than that observed during normal cycles but greater than that seen with Sequilar. During the secretion phase no appreciable differences in the penetrability of cervical mucus between the two contraceptives was observed. The hypothetical relationship between these data and the problem of cervical carcinoma was described.

Cervix Mucus↗
PubMed1977

[Investigation of pregnancy hypertension as a consequence of utero-placentar ischemia (author's transl)].

An attempt at provoking gestosis by constricting the uterine artery was made using pregnant rats and rabbits. The experiment failed. Reducing the circulation by means of Z-sutures in the region of the nidation site failed to produce symptoms of gestosis also. The result of the uterine manipulations was abortion and intra-uterine retardation of the product of conception. Though it was not possible to verify the pathogenesis of gestosis due to impaired circulation of the uterus. On the basis of these experiments previous gestosis hypotheses stemming from animal experiments cannot be questioned. However, it is though-provoking that a review of the literature reveals that the results of these "classical model experiments" cannot always be interpreted uniformly.

Animals↗
PubMed1976

[Studies on the birth-weight and the size of the new-born child with reference to the parity of the mother (author's transl)].

The relation between the parity of the mother and the birth-weight as well as the size of the new-born child, taking into account the sex, were examined as follows: From the patients needing obstretical care during the period of 1966 to 1971 those 3441 women were chosen who had born twice or more times during this time. By means of an electronic data processing system the weight and size differences of the children were correlated with the parity of the mother taking again into account the order of male and female births. Births with uncertain gestational age, non-cephalic presentations, and premature births were excluded (WHO definition or gestational age less than or equal to 266 days counted from last menstruation). 1. The average birth-weight increases by 105 g from the first to the second child, by 39 g from the second to the third, and by 12 g from the third to the fourth child. Obviously, there is no linear link between the increase of the birth-weight and the increasing parity. The major weight-increase is to be observed from the first to the second child. 2. A corresponding statement concerning the size of the new-born children cannot be made which is partly due to the relative inaccuracy of the method applied. 3. On the average boys weigh between 130 g to 150 g more than girls according to the parity.

Birth Order↗
PubMed1975

Results of in vitro sperm penetration tests in cervical mucus in the normal cycle and in mucus under the influence of the contraceptive pill.

Women who are either menstruating normally or taking a combined or sequential preparation for hormonal contraception were examined at intervals of 2 days with reference to the day of the cycle. The parameter studied was the in-vitro penetrability of the cervical mucus for sperms. Whilst the combined preparation completely blocked the cervical canal for the spermatozoa, the distance travelled by the spermatozoa under the influence of the sequential preparation was approximately the same as in the normal cycle. This study of the depth of penetration of the spermatozoa in relation to the hormonal situation was prompted not by contraceptive but rather by epidemiological considerations of cervical carcinoma.

Cervix Mucus↗