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Biomedical subjects

K Bretschneider

Publications and source records attributed to K Bretschneider.

15 recordsLinked to original sources

[A monitoring program and intervention regimen based on biological exposure tests for ensuring individual health protection of workers exposed to lead].

In Berlin a control and intervention regimen agreed upon by the Central Institute of Industrial Medicine of the GDR (ZAM) and the Industrial Hygiene Inspection of the Municipal Council has been applied in cooperation with the works health service for industrio-medical attendance of lead-exposed employees since 1984. The intervals for the check-ups by biological exposure tests are determined in higher-exposed employees resulting from blood concentration assays in addition to the legal regulations. The intervention regimen provides instructions for measures to the works doctor if the biological exposure tests indicate some high individual risk to health. The results of the application of this regimen are reported.

Air Pollutants, Occupational↗

[Characterization of exposure to pollutants in spray painting industries using room air concentration values and an exposure test].

Occupational-hygienic measurements of the interior air concentration had been performed in a large number of spray painting plants. The analyses stated that with most of the cases the exposition risk on varnishers is characterized by aerosol concentration and the concentration of lead and chromate in it. The concentrations of vapours of solvent mixtures are of subordinate importance.

Aerosols↗

Breakdown of ribosomal RNA in rabbit reticulocytes.

To study the breakdown of the RNA of ribosomes, reticulocytes from anemic rabbits were incubated in a synthetic culture medium for several hours. Ribosomal RNA was isolated from ribosomal subunits by phenol/chloroform extraction and analyzed on nondenaturing and denaturing sucrose gradients. For comparison RNA from erythroid bone marrow cells and non-incubated reticulocytes were used. The sedimentation analysis of the 28 S rRNA suggests that the breakdown during maturation of reticulocytes involves the occurrence of characteristic intermediate products, sedimenting with coefficients of about 21 S and 18 S. In contract to the breakdown of 28 S rRNA there were no apparent distinct cleavage products of 18 S RNA. The results suggest a preferential cleavage of the 28 S rRNA at specific sites, possibly owing to a particular exposure of the RNA. The breakdown of 18 S rRNA seems to occur in a random manner.

Animals↗