Biomedical subjects
Publications and source records attributed to K Buczyłko.
Reports of allergic laryngitis are sparse. This paper reports on 34 patients in order to show that laryngitis can be caused by pollens or mites with mechanisms of immediate allergy. All the cases were confirmed with skin prick tests and natural provocation in which the patients displayed a change in vocal cord status.
Food allergy and rhinitis, pharyngitis and laryngitis are discussed in relation to actual bibliography. The role and place of cromones in therapy of this food-induced allergic inflammations are presented.
The analysis of the incidence of the positive prick test with food allergens among patients with pollen allergy was performed. The 270 patients with pollinosis from four allergy centres in Poznań, Lódź and Katowice were examined. In each centres the different results were obtained. The influence for this had the different status socioeconomic of the patients, the regional habits of eating, and often eating the new products in our country. However, among examination patients the most positive test with food allergens from all centres were nuts, celery, rye flour, carrot, strawberry, pork and beans. The succession of this food allergens were changed in four examination centres in respect to the number of made prick test but the same allergens had been repeated. These results premises to establish the list of the allergens that are needed during diagnosis the patients with pollinosis.
The authors present current opinion about antiinflammatory effect of theophyllin. They describe the possibility of effective use of theophyllin in allergic rhinitis.
Interesting review of food-induced allergic symptoms in otorhinolaryngology are presented according to actual bibliography.
Frequency of positive skin in adults with asthma is poorly understood. 153 persons aged over 30 years were selected out of 575 patients suspected of asthma (26.6%). Positive skin reactions among adults, were confirmed in 64.1% of the examined patients. Positive skin reactions were analysed according to age and sex. Opinion about low frequency of allergy and asthma in elderly should be verified.
UNLABELLED: The aim of this study was to compare the efficacy of the immunotherapy by Allergovit and Catalet. 699 patient in age 5-56 were desensitized. 213 were given Allergovit: 137 in one season, 56 in two seasons and 20 in three seasons and 484 were given Catalet: 288 in one season, 151 in two seasons and 45 in three seasons. The Catalet vaccine contains 12 grasses, rye and plantain pollen, but Allergovit contains a group of grass pollen-60% and rye pollen-40%. Qualification to the desensensitization was performed on the ground of clinics symptoms, positive (+ + + +) prick skin tests, of specific antibody IgE, positive provocation nose test presence and symptoms connected with pollen fall checked every day in the area of Poznań, Lódź and Katowice city. Estimation of the immunotherapy efficiency was assessed by patients, who noted their remarks in prepared "Patient card" using enclose score. In result of desensitization by Allergovit we achieved good and very good improvement (0 + 1 score) after one desensitization season in 77.3% patients, after two seasons in 85.7% and after three seasons in 90.0%, on the contrary by patients desensibilized by Catalet results good and very good were achieved in 50% after one season, after two seasons in 63.6% and after three seasons in 77.8%. CONCLUSIONS: Better results were achieved in patients desensibilized by Allergovit than Catalet. It is necessary of compose the contain of Catalet vaccine for every patient.
208 patients between the age of 1 month to 56 years, with symptoms of respiratory tract allergy were investigated. In all cases serum titre of sIgE to birch, thymoty, rye, mugwort pollen, Alternaria Alternata, dog, cat fur, Dermatophagoides pteronyssinus and farinae was determined with the use of Quidel immunoenzymatic method. We have found sIgE to Alternaria Alternata in 8 (38%), birch pollen in 5 (23.8%) dog fur in 5 (23.8%) and thymoty and rye pollen in 3 (14.3%) even among one years-old infants. In the second and third years of life allergy to dog fur, Alternaria Alternata and pollen of birch, thymoty and rye increases while the age of 4 and 5 is less significant, later (6-10 years old patients) increases again. Among teenagers pollinosis gets decreases and adults have development constant level of the disease.
Investigations were performed on 56 children (23 girls, 33 boys), aged 0.5-16.0 (mean 7.2 years). After comparison of the ALCAT cytotoxic test results and the provocation diet results using a single blind trial, over two thirds consistency was obtained, which justified the use of the test for further analysis. The high consistency of MAST CLA and SPT suggests that in the investigated group of children IgE specific for nuts, grain, carrot, and soyabean prevailed. Comparison of these data to the ALCAT cytotoxic test gives a different view of products customarily given to allergic children. Tea, apple, coca-cola, and barley proved to be the most frequent cause of food intolerance in children investigated with the ALCAT test.
The investigated group consisted of 56 children with hay fever. The method of evaluation included interview, skin prick tests and elimination-exposure diets. Our data showed that more than half of the examined children were potentially sensitive to basic corn allergens. Currently in about one third of them clinical food allergy symptoms appeared.
The authors present the problem of endocrine function of some neoplasmatic tumors based on their own very rare case of the larynx apudoma. They pay attention to the value of some modern diagnostic methods including radioimmunological determination of the serum peptide hormone levels and some specific immunofluorescence assays with monoclonal antibodies.
The authors discuss a problem of rarely occurring bifocal carcinomas with the presentation of their own case of laryngeal carcinoma and branchiogenic cyst of the neck. They pay attention to histopathologic features underlying the diagnosis of branchiogenic cyst carcinoma and to the necessity of oncologic alertness in tumors of these kinds.
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Cytogenetic examinations were performed on 18 patients with surgically verified otosclerosis. In comparison with 15 healthy patients satellites in the somatic chromosomes of D and G groups were found to occur significantly more frequently (p less than 0.005). Moreover, among the patients a case of 45,X karyotype with clinically incomplete Turner syndrome has been disclosed. The results obtained seem to support genetic hypothesis of otospongiosis pathogenesis.
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