High-grade sarcoma of the uterine corpus with heterologous elements and synchronous adenocarcinoma in an endocervical polyp.
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Adenocarcinoma↗
Biomedical subjects
K C Coard
Publications and source records attributed to K C Coard.
Infective endocarditis at the University Hospital of the West Indies. A revisit.
Many countries have reported a change in the profile of infective endocarditis (IE) over the past three decades. The objective of this study was to evaluate the characteristics of IE from the autopsy service of the University Hospital of the West Indies (UHWI) during the last 15 years and to compare the results with that of an earlier study. There were 26 cases of IE during the period under review with a M:F ratio of 1.2:1. The ages ranged from 15 days to 74 years with a mean of 36.4 +/- 24.57 years. The largest number of cases (n = 7) occurred in the 10 to 19-year-age group. Cardiac predisposing factors were identified in 14 patients; nine with rheumatic heart disease, four with prosthetic valves and one with a bicuspid aortic valve. All vegetations were located on valves, the aortic being the most frequently involved followed by the mitral. Streptococcus species were the most common causative organisms followed by Staphylococcus aureus. Compared with the profile seen 15 years ago, there have been only minor changes in the characteristics of IE cases observed in the autopsy service at the UHWI.
Adolescent↗
Medical students' evaluation of their pathology clerkship experience.
As part of a recent trend among faculties in educational institutions to review and upgrade their courses and teaching methods, the Department of Pathology introduced a questionnaire for assessment of the pathology clerkship experience by the medical students. This was to be completed at the end of their rotation. An evaluation of the results of an entire class indicates that, for the most part, the responses were positive with 82% considering the experience to be of great benefit and 17% of reasonable benefit. The responses were generally more favorable to Anatomical Pathology and Haematology than to Chemical Pathology. The study identified areas where modifications in teaching could be considered, and ways to improve the questionnaire, making it more useful for future assessments.
Clinical Clerkship↗
Nodular fasciitis.
A 10-year review of the files of the Department of Pathology revealed 11 cases of nodular fasciitis. The clinicopathologic features of these cases are presented together with a discussion of the pathology of this lesion. The purpose of this study is to enhance both physicians' and pathologists' awareness of this entity.
Adult↗
Cardiovascular collapse in early pregnancy.
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Acidosis↗
Complete non-puerperial uterine inversion as a result of a uterine sarcoma.
Complete non-puerperial uterine inversion is rare and when present is usually associated with a prolapsed submucous fibroid. The inversion in this case was associated with a uterine sarcoma in an 88 year old diabetic patient, gravida 13, who presented with a four month history of intermittent vaginal bleeding. She was successfully managed with a total abdominal hysterectomy and some of the difficulties with diagnosis and management are highlighted.
Aged↗
Turnaround time in the surgical pathology laboratory.
One measure of the efficiency of a surgical pathology service is the rapidity of reporting the diagnosis to clinicians. The turnaround time (TAT) has been used for this purpose. This study showed that the TAT for 66% of specimens submitted to the surgical pathology laboratory in the University Hospital of the West Indies was within 3 days and for 89% within 6 days. The TAT within 7 days was considered acceptable, but it was shown that it was more than 7 days for 9%, of the specimens submitted. The importance of this information is discussed and recommendations made for identifying more accurately the source of delays in those cases in which the TAT was considered to be unusually prolonged.
Efficiency, Organizational↗
Right ventricular cardiomyopathy. A rare and underdiagnosed cause of sudden death in young adults.
We present an example of right ventricular cardiomyopathy, a very uncommon condition which caused sudden death in an adolescent boy. This case report is used to highlight the pathological features of this rare and poorly understood condition, which is often undiagnosed.
Adipose Tissue↗
Female adnexal tumour of probable wolffian origin.
We report a case of female adnexal tumour of probable wolffian origin, a rare tumour of the broad ligament, and discuss aspects of its origin, differential diagnosis and behaviour.
Adult↗
Tumours and tumour-like lesions of bone. The UHWI experience. University Hospital of the West Indies.
A review of all primary tumours and tumour-like lesions of bone diagnosed in patients who attended the University Hospital of the West Indies over a 10-year period revealed 136 cases comprising 69 benign and 54 malignant tumours, and 13 cases of tumour-like lesions. The prevalence and clinical characteristics of the various lesions are discussed and compared with the findings in other series. The results of this analysis provide demographic data useful in the differential diagnosis of bone lesions locally.
Adolescent↗
The pathology of thyroid neoplasms at the University Hospital of the West Indies. A 10-year analysis.
Thyroid neoplasms were diagnosed in 93 patients (79 women and 14 men) between January 1986 and December 1995. 52 tumours were benign and 41 were malignant. An unusual finding was that there were 16 cases each of follicular and papillary carcinomas; that is, more patients with follicular carcinomas than expected. The significance is discussed.
Adenocarcinoma, Follicular↗
Torsion of an intra-abdominal testicle in a neonate. Case report and review of the literature.
The thirty-ninth reported case of torsion of an intra-abdominal testicle is described in a neonate. The gonad was excised as is recommended because of the high incidence of malignancy (60% of 37 cases). Torsion of an intra-abdominal testicle should be considered where an abdominal mass with calcification is found in an infant with undescended testis. Ultrasonography improves the diagnostic accuracy in infants because of the cystic nature of these masses in this age group.
Cryptorchidism↗
Primary leiomyosarcoma of bone.
Primary leiomyosarcoma of bone is rare. We present the clinicopathological features of a case, the first documented from the Caribbean, seen recently at our institution.
Adult↗
Occipital osteodiastasis in Jamaica.
The Jamaican Perinatal Morbidity and Mortality Survey (1986-1987) revealed nine cases of a previously unreported form of birth-related injury in the English-speaking Caribbean--occipital osteodiastasis. Aspects of the clinical and pathological features of this form of occipital bone injury are presented and discussed. Our findings suggest that this lesion might occur more often than is currently accepted.
Birth Injuries↗
Papillary cystic tumours of the pancreas.
Papillary cystic tumour is an uncommon neoplasm of the pancreas which has only been described recently. This report describes five such cases seen at the University Hospital of the West Indies (UHWI). The clinico-pathological features were typical in all these cases. The literature of this condition is also reviewed.
Adolescent↗
Co-existing leiomyoma and benign cystic teratoma of the ovary.
A case of benign cystic teratoma and a leiomyoma in the same ovary is described. The leiomyoma was confirmed by immunohistochemical methods. The occurrence of leiomyoma and a teratoma within the same ovary is very rare.
Adolescent↗
Ruptured saccular pulmonary artery aneurysm associated with persistent ductus arteriosus.
We report a case of rupture of a saccular pulmonary artery aneurysm with fatal hemopericardium in a 29-year-old man who also had persistent ductus arteriosus with severe pulmonary hypertension. Histologic examination of the pulmonary artery showed cystic medionecrosis similar to that observed in patients with ruptured dissecting pulmonary artery aneurysms. The two types of ruptured aneurysms probably only represent different morphological expressions in the same underlying process in which the main contributory factor is pulmonary hypertension.
Adult↗
Meckel-Gruber syndrome. A lethal combination of abnormalities.
We herein describe two cases of Meckel-Gruber Syndrome identified in stillborn infants. Both had all three elements of the classical triad, namely, occipital encephalocele, renal cystic dysplasia and post-axial polydactyly. In addition, many of the other well-known accompanying abnormalities were present. Awareness of this entity in this region is important because of its high risk of recurrence in subsequent pregnancies.
Diagnosis, Differential↗