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Biomedical subjects

K C Henderson

Publications and source records attributed to K C Henderson.

11 recordsLinked to original sources

A patient with partial duplication 2q and partial deficiency 11q.

A patient with partial duplication 2q and partial deficiency 11q is reported. The propositus was delivered at 30 weeks gestation, with a birth weight of 1,390 g. He had severe hyaline membrane disease, intraventricular hemorrhage, bronchopulmonary dysplasia, hypotonia, psychomotor retardation, hearing loss, and other anomalies including a short bitemporal diameter, prominent occiput, low-set ears, exophthalmos, short nose with depressed nasal root, downturned mouth corners, narrow high-arched palate, micrognathia, a deep longitudinal groove over the sacrococcygeal region, clinodactyly, and abnormal dermatoglyphics. Chromosome analysis showed the following karyotype: 46,XY,der11,t(2:11)(q32.2;q25)pat.

Abnormalities, Multiple↗

Congenital lobar emphysema.

Congenital lobar emphysema is a rare disorder thay may present outside the newborn period. It is generally best treated surgically by excision of the affected lobe. We describe a 6 1/2-week-old infant in whom the initial auscultatory and roentgenographic findings were confusing and of no help in making the diagnosis. The etiology of congenital lobar emphysema remains unclear.

Diseases in Twins↗

Vitamin E-dependent anemia in a premature infant.

Reported is a case of a premature infant who developed a well documented hemolytic anemia which responded to vitamin E therapy. The infant developed the syndrome while receiving an artificial formula containing iron and vitamin E, plus iron supplementation. The infant had a feeding problem which may have complicated absorption of vitamin E. It is suggested that premature infants who are formula fed should not receive iron supplement until they have doubled their birth weight or have a hemoglobin concentration of less than 10 mg%. Premature infants should receive supplemental vitamin E if they are not breast fed.

Anemia, Hemolytic↗

Hydrometrocolpos in a newborn.

Hydrometrocolpos was diagnosed in a neonate shortly after birth. A large collection of fluid was immediately removed from the distended vagina; hymenotomy was performed. The infant has remained well for more than a year following treatment. A simple technique for rapid diagnosis permits safe and appropriate management of this potentially serious disorder.

Female↗