Biomedical subjects
K C Jain
Publications and source records attributed to K C Jain.
Subdural empyema due to salmonella infection.
A case of a 6-month-old child with a Salmonella subdural empyema is reported. The causative organism was never suspected until the culture report was available. The child responded well to surgical drainage and antibiotic therapy.
Splenic rupture in malignant tertian malaria.
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Pituitary abscess: a series of six cases.
Pituitary abscess is a rare condition occurring in various age groups. Only about a hundred cases have been reported in the literature. We describe six cases that constitute 0.6% of all the pituitary lesions operated at this centre in the last 10 years. All the patients presented with visual symptoms, though systemic features of infection were present in only two cases. The abscess was seen in association with adenoma in two cases and Rathke's cleft cyst in one. One patient developed an abscess following surgery for pituitary adenoma. The offending organisms was fungal in two cases, mycobacterium in one, bacterial in one and two cultures were sterile. Preoperative diagnosis is difficult and a high degree of suspicion in ring enhancing lesions of the sella is required.
Effect of phenytoin sodium in the management of poorly controlled bronchial asthma at a rural health center in Phalodi, Rajasthan, India.
The efficacy of phenytoin (PHT) for the relief of chronic asthma was evaluated in an open trial in 190 intractable rural asthmatics. Our data indicate that phenytoin (100 mg po bid for adults and 50 mg po bid for children) is a useful antiasthmatic agent used either alone, or as adjuvant therapy. Phenytoin significantly reduced the frequency and severity of asthma attacks, coughing, nocturnal awakenings, and work absenteeism, and improved effort tolerance and subjective sense of well being. Phenytoin also reduces corticosteroid requirements of steroid-dependent patients. Not only were these results sustained over the course of 12-month treatment, but more than 60% of phenytoin-treated patients could be discontinued without recurrence of symptoms.
Drug therapy falciparum malaria.
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Extension of round worm through ear.
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Pyorrhoea--a rare cause of PUO.
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Priapism in child with chronic granulocytic leukemia.
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The protective action of essential oils of onion and garlic in cholesterol-fed rabbits.
The effects of the essential oils of onion and garlic have been investigated in cholesterol-fed rabbits and have been compared with the effects of clofibrate. The marked rise in serum cholesterol and blood coagulability that followed 3 months of cholesterol feeding (0.2 g/kg/day) was significantly reduced by the essential oils of both onion and garlic. Fibrinolytic activity was actually increased even above the normal control levels. The essential oils of onion and garlic (equivalent to 1 g/kg/day of raw bulbs) proved more effective than clofibrate in the usual clinical dose of 33 mg/kg/day. Garlic was even more effective than onion. Cholesterol feeding increased the average lipid content of aorta from 5.95 to 13.75 mg/100 mg dry weight. With addition of clofibrate, onion or garlic the values were 7.79, 6.23 and 5.28 mg/100 ml, respectively. Thus it can be seen that the essential oils effectively prevent lipid acculation in the rabbit oarta.