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Biomedical subjects

K C White

Publications and source records attributed to K C White.

14 recordsLinked to original sources

The principal islet of the Coho salmon (Oncorhyncus kisutch) contains the BB isoenzyme of creatine kinase.

The importance of creatine kinase (E.C. 2.7.3.2) in endocrine tissues has been generally overlooked. Using a specific radiometric assay, we have demonstrated the existence of CK in the Brockmann body (principal islet) of the Coho salmon. We have purified this protein from insular tissue and concurrently purified CK from brain and muscle of the salmon. Purification characteristics, immunological cross-reactivity, and N-terminal sequence analysis have demonstrated that the predominant cytosolic CK from the Brockmann body is indistinguishable from the BB (brain) isoenzyme. Immunocytochemical studies indicated that the enzyme resides in the endocrine parenchyma. Phosphocreatine may serve as a reservoir of energy in the islet and augment its capacity to secrete hormones. The induction of CK-BB in the islet by other hormones could influence the secretion of insular hormones. Interorgan flux of the substrate creatine may be an undescribed mechanism of physiological regulation.

Amino Acid Sequence

Reparative dentin: factors affecting its deposition.

Results of this study showed no correlation between the thickness or amount of reparative dentin deposited and the type of dental restorative material placed at either 5 or 8 weeks in controlled Class V cavity preparations in monkey teeth. Factors such as preparation trauma from the bur, operator hand instrumentation, and microleakage of bacterial toxins played a greater role in the stimulation of reparative dentin than did material irritation or toxicity. Some differences in the thickness of the reparative dentin deposited were noted when teeth were grouped according to the amount of remaining dentin.

Analysis of Variance

Trial base adapted with sealed temporary soft liner.

Autopolymerizing acrylic resin is combined with temporary soft reline material to make a record base. Rigid acrylic resin is formed over a wax spacer. The wax is removed and the loose-fitting base is relined on the master cast with soft reline material. The soft material is cured in a pressure pot and sealed with a mono-poly mixture. Visible light-curing material can be used instead of autopolymerizing acrylic resin.

Acrylic Resins

Two-stage impression technique for overdentures.

Overdentures are supported by hard tissue and resilient tissue. Optimum distribution of functional load between these different tissue types is a challenge. A two-stage impression technique is proposed to eliminate much of the need for finished denture base modification. A first stage impression is made of the resting form of the soft tissue and is used to make a mucostatic metal base. A second impression is developed under occlusal pressure with modeling compound applied to the border and the surfaces of the metal base overlying the abutments. This procedure establishes border seal and relates ridge tissue displacement to the abutments. A final cast is made by using the metal base and modeling compound. Heat-cured acrylic resin is processed to the metal base on this cast. Adjustment of the tissue surface of the base is limited to surfaces overlying free marginal gingivae and axial surfaces of the abutments.

Alveolar Process

Fixed partial dentures opposing complete dentures.

When fixed partial dentures are indicated in an arch opposing a complete denture, it is best to develop the occlusal surfaces of the fixed restorations at the same time that the opposing denture teeth are arranged in wax to permit greater flexibility and reduce the compromise in developing bilateral balanced occlusion. This article describes the development of bilaterally balanced occlusion between casting patterns for fixed partial dentures and a complete denture. The technique emulates the ease of arranging maxillary and mandibular denture teeth and can be used to develop fixed restorations with metal or porcelain occlusal surfaces. Porcelain occlusal surfaces are described because the use of porcelain is more technique sensitive.

Acrylic Resins

Professional liability. Etiology.

Once again, I find Mr. Cooper quote-worthy for his statement, "It is incumbent upon the trial bar not to support the status quo merely because it is in our economic interest. Change is in the wind, and our tort system will be blown away on the winds of change for change's sake unless we participate in correcting deficiencies in the tort system and civil jury trial process." I suggest that we cannot ask for change for our own economic interest, nor can we lay blame exclusively to the other etiologic elements. We must improve those elements within our purview. The prayer of serenity may serve us well: God, grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference. In the game of professional liability litigation as played by the rules extant there are clearly winners and losers. The winners are the legal profession, both plaintiff and defense, and the insurers, who in the face of adversity simply increase premiums or withdraw from the market. The losers are the medical profession, the patients for whom they care and, in the broadest sense, our society as a whole. So as not to close on a note of gloom, one last quote. Lawrence H. Cooke, former Chief Judge of New York State, in remarks to the April 1986 National Symposium on Civil Justice Issues stated, "Our justice systems are beset with very real problems.(ABSTRACT TRUNCATED AT 250 WORDS)

Attitude of Health Personnel

A potentiostatic study of the corrosion behavior of anodized and nonanodized aluminum alloy.

The clinical implication of this study is that some improvement in the corrosion resistance of denture bases made with aluminum alloy D-214 may be obtained by anodization. However, since this study does not exactly duplicate an oral environment or take into consideration the variation in oral environments, it cannot be assumed that the additional corrosion resistance would be discernible in a particular patient.

Aluminum