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Biomedical subjects

K Cerný

Publications and source records attributed to K Cerný.

At least 19 recordsLinked to original sources
PubMed1992

Can carrots be addictive? An extraordinary form of drug dependence.

The paper describes three cases of dependence on carotenoids with typical symptoms of irritability and nervousness accompanying their abstinence, with a long-term dependence, and an inability to simply discontinue. Three patients (a man and two women) all being smokers, evaluated this dependence as very similar to that on tobacco. The limitation of further use had the same effect in both cases. The women evaluate the dependence as stronger than that on cigarettes, the man as somewhat weaker. The former patient--a woman--even relapsed, and recently found herself in danger of further relapse. This, however, she nipped in the bud. Laboratory enzyme examinations revealed a disorder in the enzymatic outfit affecting the auto-immunity and the neurovegetative system.

Adult↗
PubMed1992

[Adverse effects of Spophyllin Spofa Retard].

An account of reported undesirable effects of Spophyllin Spofa Retard based on the register of the Commission for monitoring undesirable effects of drugs of the Scientific Council of the Ministry of Health between December 1987 and November 1990. It is surprising that no undesirable effects of Syntophyllin and Spophyllin were reported from paediatric practice. The author submits questions associated with the discrepancy of notifications of undesirable effects of Spophyllin in adults and children.

Adverse Drug Reaction Reporting Systems↗
PubMed1992

[Tussigenic reaction after inhalation of Intal].

Sodium cromoglycate is the drug of choice in the preventive treatment of bronchial asthma. Its only undesirable effect is the tussigenic irritation of the respiratory pathways which may lead to termination of its administration. The author analyzes the causes and submits proposals for their solution.

Administration, Inhalation↗
PubMed1990

[Long-term catheterization of the central venous system in children].

The authors explain the principle of central venous catheters (CVC) for long-term use, indicators for insertion, mode of insertion and principles of care of children with these special CVC. The authors inserted since 1982 42 CVC of the Broviac-Hickmann type in 32 children (age 22 days--15 years; body weight 2.4-17 kg). Since 1987 they inserted 16 CVC for long-term use with a subcutaneous capsule to 16 children and adolescents (age 1 years-17 years; body weight 11.5-73.5 kg). These CVC were inserted under general anaesthesia, in catheterization theatre. There were no technical complications. The authors treated and followed under standard protocol a group of 14 children with 20 CVC of the Broviac type (age at onset of treatment 22-715 days; body weight 2.4-10 kg) as well as the above described group of 16 children and adolescents with CVC for long-term use with a subcutaneous capsule. During treatment of children with Broviac catheters five technical complications were observed (mechanical damage of the CVC); in children with CVC with a subcutaneous capsule one technical complication was recorded (damage of the chamber of the Chemoport Vygon system, by incorrect puncture). The authors searched for thromboembolic and infectious complications. In four of 20 children with Broviac catheters purulent phlebitis of the cannulated veins was found (all died)--one thromboembolic complication developed on average after 234 days of use of Broviac catheters.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1981

[The significance of acid phosphatase activity in the cytologic diagnosis of thyroid malignancy (author's transl)].

The activity of acid phosphatase in thyroid cells obtained by aspiration biopsy with thin needle was studied. The results were compared with those, found by a biochemical method in the operation material of the same cases. It has been proved that there is a significant difference between malignant tumours with cytochemically mostly positive acid phosphatase reaction and colloid adenomas with mostly negative reaction. The results obtained by biochemical method showed significant quantitative differences between malignant and benign tumours. The pattern of acid phosphatase subunits (isoenzymes) in the sera of patients with thyroid malignancies were pathologic and similar to those found in mammary cancers. It can be supposed that the behavior of acid phosphatase in thyreocytes depends on same metabolic properties, perhaps on some process characteristic for malignancy, e.g. growth activity. Even this finding of cytochemically positive acid phosphatase reaction cannot be awaited to be quite specific, it has proved as a useful marker signalizing the possibility of malignancy.

Acid Phosphatase↗