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Biomedical subjects

K Chintapalli

Publications and source records attributed to K Chintapalli.

17 recordsLinked to original sources
PubMed2000

9:15-9:30. Use of a Spherical 3-D Blob Analysis Program as a Method of Determination of Standardized Uptake Value (SUV) for Following Tumor Response to Chemotherapeutic Agents (CTA).

Malignant tumors exhibit increased glucose metabolism which can be quantitated by SUV. SUV is criticized for its variability resulting from many factors including the method of drawing region of interest (ROI) over the tumor. The most common method manually draws or places ROI on various slices displaying highest FDG activity. This time consuming method is associated with significant individual variation. We describe a more reproducible, efficient spherical 3-D blob analysis method of SUV and tumor volume (TV) determination to evaluate CTA response. The spherical 3-D Blob analysis program is a completely automated method with data processing performed using IDL (RS Inc., Colorado). A threshold value is set for the ROI; all voxels above threshold are grouped by connectivity. Grouped voxels, called "blobs", are displayed and statistics are calculated for each group. The threshold set for blob extraction and SUV determination is usually three times above background and is constant on repeat scans. Eight patients with metastatic carcinoma underwent PET/CT/MRI prior to and one week after chemotherapy. Three patients also had scans at one month. Maximum and average SUV's and TV were determined and appeared to be very reproducible when there was no clinical response or change on CT/MR. In these patients, repeat SUV's and volumes of the lesions (n = 38) varied by less than 20% of baseline. An increase/decrease in maximum SUV or TV correlated with a similar change in lesion size on CT/MR. The average SUV did not change. The spherical 3-D blob analysis program appears to be a reliable, efficient method of determining maximum SUV and volumetric measurements for following tumor response to CTA.

Journal Article↗
PubMed1999

Correlation of anthropometry with CT in Mexican-American women.

Measurement of regional fat has commonly been accomplished by extrapolation from anthropometric measures. Recent studies of White and Black women have demonstrated differences in intra-abdominal fat, using computerized tomographic (CT) techniques. These same estimates were computed for 48 Mexican American women who were undergoing CT for diagnostic purposes. Waist-hip ratios, waist-thigh ratios, and sagittal diameter index were also calculated. Four (7mm) CT slices between L-4 and L - 5 were analyzed with imaging software. The volume of both subcutaneous and visceral fat was estimated. Like other minority women, Mexican American women had less intra-abdominal fat than subcutaneous fat, which is important because of the association of excess intra-abdominal fat with cardiovascular risk. Intra-abdominal fat volume was significantly predicted by only one variable, sagittal abdominal diameter, while subcutaneous fat volume was predicted by hip and thigh circumferences.

Adipose Tissue↗
PubMed1997

Esophageal hemangioma.

We report a case of esophageal hemangioma presenting with dysphagia and odynophagia. To our knowledge, very few cases have been reported in the radiological literature.

Esophageal Neoplasms↗
PubMed1988

Unusual "cavity-in-cavity" appearance of pulmonary aspergilloma.

The classic radiographic appearance of pulmonary aspergilloma is a solid, round, often mobile intracavitary mass. We describe an unusual "cavity-in-cavity" appearance seen on conventional roentgenograms and computed tomography studies in two patients with confirmed pulmonary aspergilloma. We are not aware of any previous report describing such appearance based on literature search.

Aspergillosis↗
PubMed1988

Computed tomography characteristics of intermesenteric hematomas.

Abdominal bleeding may accumulate in the peritoneal cavity, retroperitoneal compartments, intraabdominal organs such as liver or bowel wall, or, rarely, in the intestinal mesentery. During the past 3 years we have encountered four cases of isolated mesenteric hematomas that were demonstrated on abdominal computed tomography examination. In this report, we present the clinical and computed tomography findings of intermesenteric hematomas with review of the pertinent mesenteric anatomy, and add four more cases to the two cases reported in two earlier reports.

Abdominal Injuries↗
PubMed1987

Primary oat cell carcinoma of the esophagus.

A case of primary oat cell carcinoma of the esophagus is presented. Clinical, radiological, and pathological findings in our case and those reported earlier were reviewed. Primary oat cell carcinoma of the esophagus should be suspected in patients with symptoms of dysphagia, radiating pain to the back with bulky mass on the esophagogram, and diffuse metastasis.

Carcinoma, Small Cell↗
PubMed1986

Gas in spinal articulations.

The purpose of this review is to illustrate, some for the first time, a variety of gas collections in lumbar facet joints and intervertebral discs and in the sacroiliac joint.

Arthrography↗
PubMed1985

Differential diagnosis of low-attenuation splenic lesions on computed tomography.

A retrospective computed tomography evaluation of proved low-attenuation splenic lesions in nontraumatic cases was done. Computed tomography was able to distinguish cystic from solid lesions. Although computed tomography examination is sensitive in the detection of low-attenuation lesions, the computed tomography findings alone are not helpful in differentiation of different low-attenuation lesions. Associated computed tomography findings in other organs and clinical findings are more helpful than the size, shape, and computed tomography attenuation of the lesions. Splenic lesions may be the only metastatic manifestation in some cancer patients. A thin needle aspiration may be done to document the nature of the pathologic lesion in problematic cases.

Abscess↗
PubMed1982

Renal fascial thickening in pancreatitis.

The incidence of renal fascial thickening in pancreatic inflammatory disease was evaluated by computed tomography. A total of 71 cases including chemical, acute complicated, and acute and chronic uncomplicated pancreatitis were retrospectively evaluated for thickening of the renal fascia. Renal fascial thickening is demonstrated in the majority of patients with complicated and uncomplicated pancreatitis. It is not demonstrated in cases of chemical pancreatitis. Renal fascial thickening is nonspecific and seen with inflammatory, malignant, and traumatic processes, but it is a valuable adjunctive sign of pancreatic inflammatory disease.

Fascia↗
PubMed1981

Perinephric abscess with renal cell carcinoma.

A case of perinephric abscess with renal cell carcinoma is presented. Hematuria is uncommon in cases of perinephric abscess. When hematuria is present in a patient with perinephric abscess further evaluation is necessary to rule out an associated malignant process.

Abscess↗
PubMed1981

Reformatted coronal display of upper abdominal computed tomography: comparison with ultrasonography.

The coronal plane is the most common format used for descriptions of the radiographic and surgical anatomy of the upper abdomen. Coronal reformatted computed tomographic (CT) studies of the upper abdomen were compared to coronal ultrasonic images of equivalent cephalocaudad dimension obtained with a water path echoscope. In most cases, the reformatted CT images were equivalent or superior in the display of selected mass lesions and their anatomic relationships. Direct coronal CT studies should be useful in the evaluation of upper abdominal pathology.

Abdomen↗
PubMedDate not supplied

Computed tomography of pulmonary thromboembolism and infarction.

Computed tomographic findings in 18 patients with pulmonary thromboembolism are retrospectively reviewed. In the majority of patients, thromboembolism was not suspected clinically. The CT findings can be divided into two groups: vascular and parenchymal changes. The most frequent vascular findings is an intraluminal filling defect or defects due to thrombus. The most frequent parenchymal finding is a triangular (wedge-shaped) pleural-based soft tissue attenuation lesion. Although CT is not a primary diagnostic tool in the evaluation of pulmonary thromboembolism, CT may be helpful in diagnosis of pulmonary embolism, when evaluating an undiagnosed parenchymal density.

Adult↗
PubMedDate not supplied

Otosclerosis: comparison of complex-motion tomography and computed tomography.

A prospective computed tomographic and complex-motion tomographic evaluation was performed in 18 suspected or proven cases of otosclerosis. Although there was good agreement between both methods, there was no greater diagnostic accuracy with computed tomography. However, computed tomography demonstrated the changes better than complex-motion tomography.

Evaluation Studies as Topic↗