PubMed Health⌕ Search

Biomedical subjects

K Cohen

Publications and source records attributed to K Cohen.

32 records · Page 2Linked to original sources
PubMed1987

[Virus diseases and cancer of the vulva].

The study of cancers of the vulva, first of all, attempts to classify precancerous lesions of the external genital apparatus. The proceedings of the ISSVD were carried out here in 1975. Clinical, epidemiological and viral arguments of HPV and HSV have been considered in order to demonstrate their responsibility in neoplasms of the vulva. However, HPV seems the main cocarcinogen. Cancers of the vulva appear, therefore, as a true sexually transmitted disease and the authors emphasize a simultaneous monitoring of the cervix and the male genital apparatus.

Adult↗
PubMed1985

Alexithymia. The development of a valid and reliable projective measure (the objectively scored Archetypal9 Test).

The aim of this study was to examine whether the Archetypal9 Test (AT9) could meet the need for a valid and reliable test with which to measure the alexithymic trait cluster. Participants in this study included 61 patients drawn from pain clinics in Montreal (Royal Victoria Hospital) and Detroit (Henry Ford Hospital) and 30 patients undergoing minor surgery at the Royal Victoria Hospital in Montreal. All 91 subjects took both the AT9 Test and the Clarke Vocabulary Scale. The results of the attempts at validation reveal that the objectively scored AT9 Test (SAT9) is a highly internally consistent instrument, that it has demonstrated construct validity, and that it can significantly discriminate between patient groups (pain patients and medical patients). The SAT9 is positively related to age, inversely related to occupational level, and uncorrelated with IQ (as measured by the Clarke Vocabulary Scale). The authors concluded that thus far, the SAT9 has proven to be a valid instrument which can be used to measure a central feature of alexithymia.

Adult↗
PubMed1984

EMG biofeedback in the modification of hypertonia in spastic dysarthria: case report.

A 22-year-old man with severe spastic dysarthria resulting from head trauma was unable to achieve mandibular closure despite traditional treatment methods. It was decided to apply the principles of electromyographic (EMG) neuromuscular re-education to increase awareness of generalized tension of the facial muscles involved in depression and elevation of the mandible. With a planned program of auditory feedback of muscle action potential, the patient displayed rapid improvement in monitoring muscle tension and achieving mandibular closure. These gains were maintained after discontinuation of biofeedback.

Adult↗
PubMed1982

Exfoliative dermatitis during cefoxitin therapy.

An 84-year-old man was admitted to the hospital with a diabetic foot ulcer and osteomyelitis of the calcaneum. While being treated with cefoxitin sodium, he experienced generalized exfoliative dermatitis, which subsided on discontinuation of therapy. To our knowledge, this is the first report of exfoliative dermatitis with a cephalosporin or related drug.

Aged↗
PubMed1980

Chronic cholelithiasis and decreased bile salt pool size: cause or effect?

The hypothesis that the decreased bile salt pool size observed in humans with chronic cholelithiasis is a result rather than a cause of gallstones was tested in a prairie dog gallstone model. A decrease in bile salt pool size was observed in cholesterol-fed prairie dogs only after the chronic presence of stones had induced physiologic, anatomic and microscopic changes typical of human chronic cholecystitis. These data suggest that the decreased bile salt pool size associated with chronic cholelithiasis is a result rather than a cause of gallstones and that the link between the hepatic secretion of cholelithogenic bile and gallstones is altered gallbladder function.

Animals↗
PubMed1978

Specificity of metabolic and circulatory responses to arm or leg interval training.

The purpose of this study was to evaluate metabolic and circulatory responses to interval training of legs or arms during steady-state, submaximal cycling. 15 college males cycled on a bicycle ergometer twice with arms (63 and 83 W) and twice with legs (100 and 125 W) before and following 5 weeks of daily interval training. Seven subjects trained with arm cycling and eight with leg cycling. Significant post-training decreases in submaximal oxygen consumption (VO2), heart rate (HR), and venous blood lactate (LA(V)) were noted when cycling with trained and untrained muscles with the magnitude of change significantly greater with trained muscles. These results indicate metabolic and circulatory adaptations to interval training that are mediated centrally and peripherally. With respect to HR, but not VO2, training a larger muscle mass (legs) produced a greater central but lesser peripheral effect whereas the opposite was true for the smaller arm muscles. The data also suggested that the peripheral adaptation involves a common mechanism controlling both HR and LA(V)) changes with a separate mechanism controlling VO2.

Adolescent↗
PubMed1978

Effects of transcorneal freezing on protein content of aqueous humor and intraocular temperature in rabbit and cat.

The effects of transcorneal freezing on protein content of aqueous humor and intraocular temperature at the posterior surface of the cornea, the angle, the iris, and the ciliary processes were determined in rabbits and cats. Normal aqueous protein concentration was 40 +/- 2 mg/dl in rabbits and 43 +/- 4 mg/dl in cats. In rabbits, total aqueous protein content reached its highest level (2790 +/- 302 mg/dl) for 3 hr after transcorneal freezing, decreased by 50% after 4 hr, and was not significantly different than normal at 7 days. In cats, total aqueous protein content also reached its highest level (1610 +/- 290 mg/dl) 3 hr after corneal freezing. Fluctuations occurred thereafter, but protein content was not significantly different from normal after 7 days. The temperature at the corneal endothelium always decreased to below 0 degrees C with a 10 to 25 sec application of the cryoprobe to the cornea in rabbit and cat. Intraocular temperature did not decrease below 24 degrees C at the angle or ciliary processes during application of the cryoprobe for up to 25 sec, whereas the temperature at the pupillary margin of the iris sometimes decreased to near 0 degrees C with a 15 to 25 sec application.

Animals↗
PubMed1976

Cornifying Darier disease--a unique variant. I. Report of a case.

A unique variant of Darier disease is described in which a patient was disabled by large, painful, cutaneous horns present on all extremities. The cornified lesions were distinguished by the presence of numerous corps ronds in the basal portion of the greatly hyperkeratotic stratum corneum, hypertrophic dermal villi containing enlarged capillaries, vacuolar dilatation of rough endoplasmic reticulum in sublacunar basal cells, unusually numerous Odland bodies in spinous cells adjacent to lacunae, and persistent attachment of tonofilaments to disrupted desmosomes. Complete separation of tonofilaments from intact desmosomes was not observed. Scanning electron microscopy revealed varied surface morphological appearances of corps ronds and of the epidermal cells covering the elongated dermal villi. The surface cells of cutaneous horns showed little tendency to desquamate.

Adult↗
PubMedDate not supplied

HMO innovations. Video-enhanced medical advice; senior zoo walkers; Group Health Resource Line; enhancing health education programs through desktop publishing; home health beat; innovative school health partnership.

The editors of HMO PRACTICE asked clinicians and health educators in HMOs across the country to submit reports on their unique, successful patient education programs. The following HMO Innovations testify to the wide range of new technologies, enterprising partnerships, and creative ideas that are shaping health education in HMOs today.

Creativity↗