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Biomedical subjects

K Cullen

Publications and source records attributed to K Cullen.

46 records · Page 3Linked to original sources
PubMed1982

Adverse psychological sequelae associated with total joint replacement surgery.

Although total joint replacement surgery is generally successful in pain relief and improved joint function, adverse psychological sequelae sometimes do occur. This report highlights potential problems associated with total joint replacement surgery and illustrates with brief cases from a referral hospital for arthritis patients. An appreciation of psychological factors can ensure patients' motivation to participate in the rehabilitative efforts after surgery, and thus enhance optimal results from the surgery.

Adaptation, Psychological↗
PubMed1982

Alcohol and mortality in the Busselton study.

Non-smoking Busselton men and women who classed themselves in 1966 as non-drinkers had significantly higher 13-year mortality from all causes and from cardiovascular disease (CVD) compared with non-smoking drinkers. Such findings are the first to be reported in women. Smoking had no observed effect on the mortality of Busselton's non-drinkers, but in drinkers, smoking was associated with significantly higher mortalities from all causes CVD, CHD, and cancer compared with those of smoking non-drinkers. For all subjects, the recent prospective studies from Busselton and other selected populations have indicated that the lowest rates of total mortality have been found in those whose daily alcohol consumption ranged between 1-30 mls/day.

Adult↗
PubMed1982

Electrocardiograms and 13 year cardiovascular mortality in Busselton study.

In 2119 unselected Busselton subjects 40 to 79 years of age, the 13 year mortality from cardiovascular disease was significantly higher in those whose initial electrocardiogram showed Q and QS patterns, left axis deviation, ST depression, T wave depression, flat or biphasic T waves, atrial fibrillation or flutter, and ventricular extrasystoles. In angina-free subjects whose electrocardiographic codes occurred in isolation from any other electrocardiographic abnormality, ventricular extrasystoles were associated with significantly higher mortality from cardiovascular disease compared with controls.

Adult↗
PubMed1982

Reversible loss of nocturnal penile tumescence during depression: a preliminary report.

Depressed patients regularly report a loss of interest in sex, but whether this represents only a lack of psychological motivation or is a reflection of an underlying physiological abnormality is unknown. We have studied 2 men suffering from severe depression and have observed that nocturnal penile tumescence was virtually absent while the men were depressed but returned to normal on recovery.

Aged↗
PubMedDate not supplied

Topography of brain atrophy during normal aging and Alzheimer's disease.

The present study investigated the effect of age on total and regional brain volumes and compared age-associated changes in 20 healthy controls with those observed in 12 patients with Alzheimer's disease (AD). Weights and volumes of the whole brain and cerebrum, as well as the fractional volumes of the frontal, temporal, and parieto-occipital cortices, medial temporal structures, deep brain structures, and white matter were measured. Males had larger and heavier brains than females of comparable age. A small decline in brain volume with age was found (approximately 2 ml per year), but only within the white matter. In comparison, no further loss of white matter occurred in AD; however, the cerebral cortex was significantly reduced in volume, with the greatest loss from the medial temporal structures. This loss was related to disease progression; greater proportional loss was associated with more rapid decline in older patients. This study suggests that significant brain atrophy is not a consequence of advancing age. In addition, it suggests a regional specificity of damage in AD.

Age Factors↗