[Evaluation of hippuric acid excretion after toluene exposure by systematic detection of impairment].
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Biomedical subjects
Publications and source records attributed to K D Bergert.
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In inhalative toluol loads lasting one hour a dependence of the secretion of hippuric acid on the concentration of toluol in the inspiration air influenced by the respiratory minute volume was shown. It is concluded that the estimation of the hippuric acid from a one- to two-hours' collective urine of the working shift may give actual references to the toluol load. The increase of hippuric acid in the urine of 1.5 g/l after toluol exposition refers to the transgression of the MAK-values according to TGL 22310.
In a model experiment 8 test persons each were given 1 mg and 2 mg fluoride per os. In a subsequent period of urine collection of 4 hours on an average 10% of the adduced fluoride were eliminated. Taking into consideration extraprofessional intake of fluoride may be concluded that the estimation of fluoride in the urine of welders working with Kb-electrodes may give references to the individual load of the respiratory tract by weld fumes.
On 62 welders and in a control group consisting of 90 test persons dynamic functional parameters of the lungs were established. In these cases welders older than 40 years after an activity lasting at least 2 decades gave references to a chronic obstructive disease of the respiratory tract, which after exclusion of other etiological factors may be regarded as a sequel of irritatively and toxically effecting welding fumes and gases.
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