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K D Bhoola

Publications and source records attributed to K D Bhoola.

139 records · Page 8Linked to original sources
PubMed1968

Intracellular distribution of submaxillary kallikrein.

1. Differential centrifugation and sucrose density-gradient data indicate that kallikrein in the submaxillary gland is associated with particles which sediment with the nuclear and heavy mitochondrial fractions and equilibrate with 1.7-1.8 M sucrose.2. The sedimentation properties of the kallikrein containing particles differ from those of mitochondria and lysosomes, but resemble those of the pancreatic zymogen granules.3. Histological observations indicate that kallikrein is associated with basophilic particles which stain positively with Periodic Acid-Schiff reagent.4. Pilocarpine causes a preferential secretion of kallikrein and amylase into saliva.5. The results would support an exocrine role for submaxillary kallikrein.

Acid Phosphatase↗
PubMed1966

The subcellular localization of kallikrein, amylase and acetylcholine in the submaxillary gland of the guinea-pig.

1. The subcellular distribution pattern of kallikrein was compared with that of amylase and acetylcholine in submaxillary gland homogenates of the guinea-pig.2. Kallikrein was located in particles which sedimented in the nuclear (46%) and mitochondrial (17%) fractions. These particles were probably similar if not identical to zymogen granules.3. The above observations would support a digestive role for salivary kallikrein.

Acetylcholine↗