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Biomedical subjects

K D Gode

Publications and source records attributed to K D Gode.

16 recordsLinked to original sources
PubMed1984

Curcuma longa (Linn) drops in corneal wound healing.

In this study, an attempt has been made to evaluate the cortisone like inhibitory activity on healing of wounds of curcuma longa extracts-aqueous extract (2.8%) and alcoholic extract (1.125%) on the healing of superficial and penetrating corneal wounds in albino rabbits. It was observed that curcuma longa aqueous drops (a) definitely delayed healing of superficial corneal wounds (P less than 0.001), (b) delayed healing of penetrating corneal wounds also and markedly reduced the tensile strength of corneal wounds (P less than 0.02), when comparison was made with placebo and preservative drops.

Animals↗
PubMed1982

Functional beta cell regeneration in the islets of pancreas in alloxan induced diabetic rats by (-)-epicatechin.

(-)-Epicatechin (1), a naturally occurring flavonoid compound was found to have reversed the diabetogenic action of alloxan in albino rats (2). (-)-Epicatechin administration in doses of 30 mg/kg (i.p.) twice daily for 4-5 days in alloxan induced (150 mg/kg, i.p.) diabetic albino rats (either sex), has brought down the high blood sugar levels to normal values. Concurrent histological studies of the pancreas of these animals showed regeneration of the beta-cell population of the islets which were earlier necrosed by alloxan. Immunoreactive insulin (IRI) studies showed that the regenerated beta-cells of the islets of pancreas are functional in nature.

Animals↗
PubMed1974

Effects of propranolol on gastric secretion in albino rats.

1 Effects of graded doses of propranolol have been studied on gastric secretion and gastric ulcers in pylorus-ligated rats.2 A dose-dependent action of propranolol was observed; small doses increased total volume, acid output and pepsin secretion along with an increase in the incidence of ulcers but high doses were inhibitory.

Animals↗