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Biomedical subjects

K D Hofmann

Publications and source records attributed to K D Hofmann.

34 records · Page 2Linked to original sources
PubMed1977

[Beta-glucuronidase activity in human ovarian tissue during the life- and cycle-phases of the woman].

The behaviour of the beta-glucuronidase activity during the life phases and the phase of the cycle of a woman has been studied in 51 human ovaries after the Dohrmann method. The study clearly indicates a dependency on age, that is demonstrated by a rise in beta-glucuronidase activity from 536 microgram Ph/h/g ovarial tissue during full functioning to 705 microgram Ph/h/g ovarial tissue in the premenopause and by dropping to 529 microgram Ph/h/g ovarial tissue in the menopause and the senium. The premenopause values are significantly higher compared to that of the other two functional phases. The activity of the beta-glucuronidase is significantly higher in the secretory phase than in the proliferation phase. Existing relations between the beta-glucuronidase of the ovary and the gonadotropic hormones of the hypophysis and the oestrogen metabolism are discussed.

Adult↗
PubMed1976

[Function of thrombocytes during the gestational period and puerperium and their relation to the occurence of thromboses. 2. Function of blood platelets during late pregnancy, labor and puerperium in gestosis].

Platelet functions during late pregnancy with praeeclampsia, birth and childbed were observed. There are found variations in opposition to normal pregnancy. Increase of platelet aggregation was clearest. In this observations is not conclud from increase risk developing a thromboembolic disease during toxemic pregnancy, birth and childbed. The variations of platelet functions are parts of complex appearence.

Female↗
PubMed1976

[Modification of the thrombocyte function using hormonal contraception. 1. Thrombocyte count, thrombocyte propagation and platelet aggregation under hormonal contraception].

The number of platelets, spreading and aggregation of platelets in plasma of 102 women treated with Ovosiston, an anticonceptive agent, were investigated. A significant increase of the number of platelets, spreading and aggregation of platelets was observed. Conclusions from isolated observations are not possible.

Adolescent↗
PubMed1976

[Modification of the thrombocyte function using hormonal contraception. 2. Platelet adhesiveness, thromboelastography, conclusions].

Platelet adhesiviness and thrombelastographic investigations in plasma by 102 women treated with Ovosiston, an anticonceptive agent were observed. A significant increase of adhesiveness and thrombelastographic variations was found. In conclusion showed abnormalities of platelet functions and thrombelastographic values point to influences by oral contraceptive agent Ovosiston. In combination with other favouring factors the risk of thromboembolism must be enhanced.

Blood Coagulation↗
PubMed1976

[Modification of glycylglycine dipeptidase activity in the human ovary using follicle stimulating hormone. I].

The glycyl glycine dipeptidase activity under the in vitro influence of two follicle-stimulating hormone preparations of different concentration was investigated in 36 ovaries. A significant impediment was observed under Folistiman, whereas under Anthrogon the impediment could only be detected with higher concentrations. The FSH/ICSH relation evidently plays an important role in this respect. The results are in support of the statement that the glycyl glycine activity in vivo also depends on the gonadotrophin production. At the same time they affirm the fact that not only endopeptidases play a role in the hormone metabolism of the ovary.

Adnexa Uteri↗
PubMed1976

[Function of thrombocytes during gestation and puerperium as well as their relations to thrombosis. 1. Function of blood platelets in normal pregnancy, during labor and puerperium].

Platelet functions during late pregnancy and puerperium were observed. It was found pregnancy variations of the number of platelets, platelet spreading, -aggregation, adhesiveness and thrombelastographic investigations. In this observations is not conclude from increase risk developing a thromboembolic disease during pregnancy and puerperium.

Blood Platelets↗