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Biomedical subjects

K D Panikratov

Publications and source records attributed to K D Panikratov.

At least 19 recordsLinked to original sources

[Modified technique of ureterocystoneostomy].

The authors describe a technique of ureterocystoneostomy based on the principle suggested by Politano-Leadbetter but using an original set of instruments approved by the patent committee. The technique was applied in the treatment of 12 children aged 11 months to 5 years. The operation was highly effective: it became easier to perform in reduced duration and traumatism.

Anastomosis, Surgical↗

[Immunity status in early postoperative complications in children with anomalies of kidneys and upper urinary tract].

31 children aged 1 to 9 years with malformations of the kidneys and upper urinary tracts were preoperatively examined for immune status. After plastic operation 14 children developed early postoperative infectious-inflammatory complications. It is suggested that early postoperative complications in some children with renal and upper urinary tract maldevelopments may arise because of weak compensatory abilities and immunodeficiency resultant from the operative stress. These created favourable conditions for activation of latent infection. Immunological assessment of the patient prior to surgery predicts early postoperative complications and thus enables proper preventive measures.

Child↗

[Some features of recovery of upper urinary tract urodynamics after surgical treatment of vesicoureteral dysplasia in children].

Urodynamics of the upper urinary tract (UUT) was examined in 327 children aged 1.5 months to 15 years with congenital vesicoureteral reflux (VUR) dysplasia treated surgically. 230 patients were followed up for 1 to 20 years. Staging of chronic disorders of UUT urodynamics is thought to be the key criterion of objective assessment of VUR effective surgical treatment. The better long-term treatment outcomes are the earlier the disease was diagnosed and corrected. Early defects of urodynamics in the absence of marked dilatation of the ureter are better corrected by Lich-Gregoir operation which is physiological, low traumatic, technically available and most effective (97% of favourable long-term outcomes). Ureterocystoneostomy by Politano-Leadbetter (in modification of the authors) is indicated in urodynamic disorders stage III and marked ureteral dilatation as providing improvement of urodynamics or stabilization in 93.7% patients.

Adolescent↗

[The role of nitric oxide in fertility disorders in men].

The aim of the study was investigation of NO influence on fertility properties of ejaculate in the diseases of male sex organs. A total of 73 males aged 20-55 years with different sexual disorders were examined. Potentiometric assay for nitrates in ejaculate, size and shape of spermatosoa were studied. NO3 was present in all sperma samples. In the control group nitrates levels were 0.662 +/- 0.147 mmol/l. In men with sexual diseases nitrates levels in ejaculate ranged from 0.114 mmol/l to 1.530 mmol/l). In normozoospermia nitrates occurred in "mean" levels (0.295 mmol/l to 0.900 mmol/ 1). In pathospermia nitrates level was high. NO produces a protective action if it was in adequate quantity. Spermatozoid concentration and a relative number of progressive-mobile forms correlated negatively with nitrates of spermatic plasma (r = -0.40) while dead spermatozoa percentage correlated positively. Thus, low NO3 content in ejaculate may result from microcirculatory disorders and endothelial dysfunction in testicular parenchyma and epididimus. NO hyperproduction occurs in inflammatory urogenital diseases. It probably induces pathospermia via direct toxic effects of NO and stimulation of lipid peroxidation.

Adult↗

[The surgical treatment of penile oleogranulomas].

The paper provides some experience in treating penile paraffinomas in 24 patients, 8 of whom had abnormal changes in the distal penis. Circular dissection of the prepuce was performed within normal tissues. Paraffinoma and skin of the whole penis were removed in 16 patients with penile skin and fat lesions. Then a 5 x 20-cm dermal graft (or two 5 x 10-cm grafts) was taken from the anterolateral surface of the femur. Holes 1-2 cm apart were made with a scalpel over the whole graft surface and dermoplasty was performed with a perforated graft, which was tightly put, without pulling on the penis from above and below. The distal and proximal portions of the graft were attached to the skin of the coronary sulcus and the base of the penis with loop catgut sutures. The surgery ended with application of a propocium dressing to the penis and aseptic dressing to the femur. Good results were achieved.

Adolescent↗

[Combined urodynamic insufficiency in patients with an infravesical obstruction].

Functional activity of the lower and upper urinary tract was examined in 169 patients with infravesical obstruction and in 20 controls. Combined investigation included: radioisotope uroflowmetry, retrograde cystomanometry, urethrosphincterometry, miction videocystourethrography, excretory urography, radioisotope renography, pharmacorenography, dynamic nephroscintigraphy and renal angiography. An analysis of lower urinary urodynamic findings has demonstrated stages as an important regularity in the development of functional lower urinary disturbances. As a result, a standard system has been evolved for the assessment and classification of stages in chronic lower-urinary urodynamic disorders. Four stages are identified in the classification. Evaluation of upper-urinary urodynamics in the same 169 patients with lower urinary tract disorders of varying severity demonstrated that upper urinary functional parameters become worse as lower urinary parameters deteriorate, but there is no strict correlation between those. A systematic study of the pattern of combined disorders of the lower and upper urinary tract has made it possible to develop a standard system for the assessment and classification of stages of combined urodynamic insufficiency, with 4 stages identified. The use of this system improves objective assessment of the severity of patient's condition and specifies indications for surgical treatment of infravesical obstructions.

Chronic Disease↗