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Biomedical subjects

K D Richter

Publications and source records attributed to K D Richter.

At least 37 records · Page 2Linked to original sources
PubMed1984

[Uncemented total prosthetics as exemplified by a carbon-fiber prosthesis of the hip joint].

A new artificial total hip joint was designed and tested in animals and human patients up to five years. For implant combined carbon material (Endocarbone) was used. The primary anchorage was achieved by a hydraulic pin system without bone cement. The follow-up of bone growth at the implant bone border line was proved by X-ray, computer-tomography, arthrography and histo-morphological tissues. The Endocarbone hip prosthesis has been proved as a biological implant. The good bonely incorporation justifies a more intensive clinical testing.

Animals↗
PubMed1982

[Bone healing and dynamic interferential current (DIC) (author's transl)].

The aim of this investigation was to clarify the influence of dynamic interferential current (DIC). Two sinusoidal currents of medium frequency are superimposed within the body to determine the reactive changes of bone healing after osteotomy. An osteotomy was performed on the radius and ulna of the right foreleg of 34 'black-head breeding sheep'. The radius shaft was deperiostalized and unstably fixed with a four-hole AO-plate leaving a gap of at least 1 mm width. DIC of different mA-values were not treated 24 sheep 3 times per week for 10 mins. The other 10 animals were not treated with DIC but used as control animals. The different results of our clinical, radiological, histological and chemical analyses to date indicate that callus formation is accelerated by the application of DIC. The fracture callus of treated animals is strongly mineralized.

Animals↗
PubMed1982

[Bone healing and dynamic interferential current (DIC) (author's transl)].

In the course of supplementary physical and chemical investigations of the influence of Dynamic Interferential Current (DIC) on bone healing 24 black-head sheep were subjected to transversal osteotomy of the radius. After an instable osteosynthesis the site was exposed to repeated therapy with DIC of varying mA intensity. (Methodological details are described in part I). DIC therapy resulted in altering the temperatures in the treated tissue, dependent on the mA intensity. Further associations were verified between DIC intensity and the occurrence of hydroxyprolin, and amino acid specific collagen, which also reflected increased calcifying activity. Measurement of the calcium and phosphorus levels in the regenerated (newly forming) bone tissue documented full mineralization in the DIC-treated animals at a much earlier date than in the untreated controls that had undergone similar operations. Whether DIC specifically stimulates osteogenesis within "healing" bones is still unclear.

Alkaline Phosphatase↗
PubMed1980

Effect of extracorporeal blood irradiation on lymphocytes and the lymphatic tissue in a goat.

In a long-term study discontinuous extracorporeal blood irradiation (ECIB) was applied to a goat using a 500 Ci-137 Caesium source. Lymphocytes of the peripheral blood were examined by light and electron microscopy. After application of a transit dose of 466,500 rad the lymphocytes in the peripheral blood were found to be decreased from 6,900/microliter to 500/microliter, revealing a complete dissolution of the nuclei in electron microscopic preparations. Histological examinations showed a severe atrophy of the whole lymphatic tissue.

Animals↗
PubMed1980

[Cement-free fixation of a stemless total knee endoprosthesis in animal experiments (author's transl)].

A stemless total knee endoprosthesis with physiological kinematics (slip and rolling motion, tibial rotation) and cement-free primary fixation (straddling dowel and thread system) was tested in animal experiments. The fixation allows total functioning of the operated extremity from the first day after operation. Primary results and follow-up for 40 weeks after operation reveal satisfactory results, especially with regard to durable bony incorporation of the prosthesis as shown by histologic and microangiographic studies.

Animals↗
PubMed1979

[Acute pancreatitis in animal experiments - a new method].

Acute pancreatitis was induced in 30 minipigs (Göttingen) by implantation of a T-drain into the Ductus Wirsungianus. The distal part of the T-drain, which led into the duodenum was stenosed to 1/3 of the original diameter. The inflammation was caused by stenosis of the Ductus Wirsungianus additionally by application of contrast medium. The course of the inflammation was demonstrated by biochemical, roentgenological and histological examinations.

Acute Disease↗
PubMed1979

[Experimentally induced pancreatitis (author's transl)].

Pancreatitis was produced in 29 mini-pigs by partial occlusion of the pancreatic duct; occlusion was performed by implanting a T-drain into the duct. Inflammatory changes were induced additionally by applying radiopaque material in excess. Acute and chronic pancreatitic lesions could be diagnosed by X-ray examination, evaluation of blood chemistry and by histology.

Amylases↗
PubMed1978

[Animal experimental studies of hemolysis following extracorporeal blood irradiation].

In experimental studies on animals, extracorporal blood irradiation was performed in 3 sheeps and 1 goat by means of 500 Ci 137 cesium source. The sheep died of the sequelae of narcosis, with anaemia being only moderately marked. In the goat a transit dosis of 466566 rad could be applied before the animal died of the sequelae of haemolytic anaemia.

Animals↗