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Biomedical subjects

K D Schmidt

Publications and source records attributed to K D Schmidt.

10 recordsLinked to original sources
PubMed1992

Thermoregulation and fever in normal persons and in those with spinal cord injuries.

Thermoregulation and fever are primarily mediated through the hypothalamus and its effector mechanisms. In persons with complete spinal cord injuries above T-6, thermoregulation is substantially impaired because of the interruption of neuronal pathways to and from the hypothalamus. These same pathways are important in the production of fever in response to infections, and injury to these pathways in patients with high-level spinal cord injuries should diminish their ability to mount a febrile response. In clinical practice, however, measurements of body temperature are used to make decisions in patients with spinal cord injuries in a manner similar to that in patients without spinal cord injuries. In this article, we review the literature on thermoregulation and fever in normal persons and in those with complete spinal cord injuries and propose possible mechanisms for fever in persons with high-level spinal cord injuries.

Body Temperature↗
PubMed1984

[Differential choice of the procedure in the surgical treatment of fractures in the trochanteric area].

718 trochanteric fractures, surgically treated with nailing according to Ender, 130 degrees angled blades of AO, 95 degrees condyle blades of AO, valgisation blades of AO and the (DHS) dynamic hip screw of AO were followed up for anatomical reconstruction, early weight-bearing, complications and spectrum of indication. The best surgical method is the DHS-osteosynthesis, easy to perform, weight-bearing at once, low rate of complications and good results by a broad spectrum of indications. Subtrochanteric fractures should be treated with 95 degrees condyle blade and unstable fractures connected with destruction of Adam's bow with valigisation osteotomy and valgisation blade.

Bone Nails↗
PubMed1981

Viscosity and electrolyte concentrations in gastric juice from cystic fibrosis children compared to healthy children.

The viscosity of gastric juice and the concentrations of sodium, potassium, calcium, magnesium and chloride ions were measured before and after stimulation with pentagastrin in 10 children with cystic fibrosis and compared to those in 10 healthy children of corresponding ages. The viscosity values followed the same patterns as those for the sodium and calcium ion concentrations and were higher in the cystic fibrosis group. The electrolyte concentrations in the basal and different post-stimulation fractions of the gastric juice were higher in the cystic fibrosis group. Significant differences between both groups could only be found in the electrolyte concentrations. The total secretion of each of the electrolytes was the same in both groups because along with the increased electrolyte concentration in the cystic fibrosis group there was a reduced volume of gastric juice. The dependence of viscosity on the individual electrolyte concentration is discussed. The differences in the viscosity and the electrolyte concentrations in gastric juice from the cystic fibrosis children seems to be due to changes in the process of gastric secretion and not due to the influence of swallowed saliva.

Calcium↗
PubMed1980

[Contamination of milk after teat redisinfection with iodophores].

The passage of iodine to milk after drug redisinfection with iodophores developed in the GDR and the Polish People's Republic has been studied by labelling these preparations with iodine-131. The iodine contents found in the milk lay below the internationally indicated limits of tolerance. Therefore, from the hygienic-toxicological point of view, the use of these iodophore variants might be considered safe, provided that they were employed properly.

Animals↗
PubMed1980

Distribution of hypertrophic pulmonary osteoarthropathy.

Radionuclide bone scanning is a sensitive detector of new bone formation. It offers the possibility of more complete description of the distribution of hypertrophic pulmonary osteoarthropathy. The scintigraphic findings in 48 confirmed cases of hypertrophic pulmonary osteoarthropathy (HPO) are described. Several new observations about the involvement of bones and distribution pattern have been made: the skull (mandible and/or maxillae) was involved in 42% of cases, the scapulae in 67%, and the patellae in 50%. Clavicles were involved in 33% of cases. With the exception of the humerus, the proximal and distal portions of each long bone were involved with equal frequency. Involvement of the extremities was invariably present, and disease almost always appeared more active in the lower than in the upper extremities. Asymmetric involvement of the extremities was noted in 17% of cases, and there was irregular involvement in 15%. Differentiation of metastatic disease from HPO by bone scanning is generally not difficult, since the most frequent patterns of distribution of these two conditions are entirely different.

Adolescent↗
PubMedDate not supplied

[Case studies of the effect of tyrosine administration in children with phenylketonuria on cognitive processes].

Eight patients with phenylketonuria and low protein nutrition were treated in a double blind crossover study for the time of 3 month with 150 mg tyrosine per kg body weight and day and placebo thereafter or vice versa. The concentration of phenylalanine in serum was not influenced by the administration of tyrosine whereas tyrosine in serum markedly increased. Psychological tests were 7 times repeated in monthly intervals. From the study it is to suggest that there is an improvement of the test results caused by an effect of training due to the repeated tests and an additional improvement caused by tyrosine.

Attention↗