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Biomedical subjects

K D Thomas

Publications and source records attributed to K D Thomas.

27 records · Page 2Linked to original sources

Changes in the blood and foetal fluid composition at different stages of gestation in ewes.

In 15 West African Dwarf ewes blood and foetal fluid were collected and investigated on the 50th, 100th, and 150th day of gestation in order to determine normal values. The foetal fluid increased in volume and weight from day 50 to day 150. It was clear, colourless, and slightly viscous by day 50, but creamy, more viscous, and mucoid by days 100 and 150. The number of cellular blood components was dependent on the gestational age. The same was found for electrolytes, cholesterol, total proteins, albumins, and globulin in the blood and amniotic fluids.

Allantois↗

Effect of high protein diet on the haematology and plasma biochemistry of puberal West African dwarf rams.

In 10 West African dwarf rams, 5 of which were fed forage only and 5 an additional concentrate (14% protein), several biochemical and morphological blood parameters were determined weekly for 5 weeks. The concentrations of urea, albumin, globulin, cholesterin, alkaline phosphatase, and creatinine as well as the number of white blood cells, neutrophil and eosinophil leucocytes exhibited dependencies on the type of feed.

Alkaline Phosphatase↗

Plasma biochemical parameters West African dwarf rams and their crosses with Permer.

The West African dwarf (WAD) is the prevailing breed in the South Western part of Nigeria, whereas Permer (P) is a cross of Persian and Merino sheep. Since the mortality rate is unacceptably high in Permer-even under favourable conditions-several plasma variables were determined in 5 WAD and WAD X P rams twice on Mondays over 5 weeks with a view to health prophylactic measures. Differences between the breeds were found that did not, however, in any case agree with the values found by other authors and that suggested a connection with certain diseases. This should be investigated in investigations to come.

Alkaline Phosphatase↗

Haematology of the crosses of West African dwarf rams with Permer and their castrates.

The haematological status of five West African dwarf (WAD) x Permer (P) rams and five WAD x Permer castrated rams (PC) was determined at 9.00 a.m. and 6.00 p.m. every Monday for five weeks. The variables measured were: haemoglobin content (Hb), packed cell volume (PCV), mean corpuscular haemoglobin concentration (MCHC), platelet (P), white blood cell (WBC), neutrophil (N), lymphocyte (L), monocyte (M), and eosinophil (E) counts. With the exception of N, L, and E, the values were not constant. The values of WBC, N, and L depended on the type of ram used. The time of the blood collection affected the Hb, WBC, and E concentrations. The value of M varied most (depending on the time of blood collection, week of determination, type of ram).

Animals↗

Peripherally inserted central catheters: placement and use in a family practice hospital.

BACKGROUND: The peripherally inserted central catheter (PICC) is increasingly used in protracted intravenous therapy. The device has several advantages for family practice, but its use has been chiefly described in nursing and interventional radiology literature. We investigated the use of the PICC in a family practice teaching hospital. METHODS: Forty PICCs were inserted from 1993 to 1995 in 29 patients. Available records and radiographs were reviewed for indication, nature of placement attempts, indwelling time, PICC role in therapy, and attendant complications. RESULTS: Successful placement was achieved in 95 percent of instances requiring PICC use. Fluoroscopically guided placement, usually without venography, was found to be preferable to unguided bedside placement. In a few cases in which PICCs were placed, no other access was subsequently required to complete therapy. Few clinically serious complications were encountered. Most complications were related to placement at bedside. CONCLUSIONS: Our experience supports the PICC as a minimally invasive, economical alternative for protracted intravenous therapy. Fluoroscopically guided placement was found preferable to unguided bedside placement. Physicians ordering or placing PICCs should understand fully how to assess placement.

Adolescent↗