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Biomedical subjects

K Dawidowsky

Publications and source records attributed to K Dawidowsky.

7 recordsLinked to original sources

Experimental hematotympanum--aspects to the tympanosclerosis development.

The etiology of tympanosclerosis is very complex and has not been entirely clarified. In order to find out if blood could be a provoking factor and cause tympanosclerosis, the authors injected the blood into the ears of 32 guinea pigs. The animals were sacrificed at weekly intervals up to one month and the histological analysis of the temporal bones was performed. Their experiment has shown that mucosal changes, similar to those seen in the early stage of tympanosclerosis, can appear in a certain number of cases. As a result, they recommend the aspiration of blood from the middle ear cavity in the cases of middle ear trauma with hematotympanum. They recommend the same procedure for operations of the middle ear, which should be performed with adequate hemostasis to prevent possible tympanosclerosis development.

Animals↗

Changes of intratympanic pressure in secretory otitis media.

A thick, gluey effusion was observed to out of the middle ear after myringotomy only in some cases of secretory otitis media. Cytologic analysis of intratympanic transudate in 321 cases of secretory otitis media in children showed the cellular infiltration to result in increased viscosity of the middle ear content. It caused gradual change in the middle ear pressure, from the initially negative to positive pressure in the advanced stages of the disease.

Adolescent↗

Tympanoplasty after war blast lesions of the eardrum: retrospective study.

AIM: To establish whether hearing loss after eardrum blast injury could be recovered by tympanoplasty performed immediately after injury and what material is the most suitable for eardrum closure. METHODS: Tympanoplasty was performed in 119 (a total of 181 injuries) out of 651 patients examined for blast injury of the ear between 1991 and 2000. The study included a total of 106 patients who underwent tympanoplasty: 51 patients with unilateral and 55 with bilateral blast eardrum rupture (a total of 161 injuries). Three different materials were used for eardrum rupture closure: temporal fascia in 81, perichondrium in 61, and heterograft in 19 cases. Injuries were divided in 4 groups, according to the time elapsed between the injury and tympanoplasty (0-20, 21-60, 61-180, and 181 days and more). Otomicroscopic finding, audiometry, and tympanometry were used for definitive evaluation of tympanoplasty outcome. RESULTS: Eardrum rupture was successfully closed with temporal fascia in 91%, perichondrium in 92%, and heterograft in 89% of the cases (p=0.429). There were no statistically significant differences in either values of postoperative air- bone gap (p=0.210) or in eardrum perforation closure rate (p=0.951) with respect to the time period between the injury and tympanoplasty. Also, there was no correlation between the postoperative air-bone gap and the number of days elapsed between the rupture and tympanoplasty (r=-0.037, p=0.641). CONCLUSION: Small ruptures of the eardrum should be left to heal spontaneously. The patients with subtotal and total rupture and rupture that did not heal spontaneously in three months should undergo tympanoplasty. Temporal fascia, perichondrium from tragus, and heterograft are equally acceptable materials for eardrum closure after blast injury.

Blast Injuries↗

Vasodilator and vitamins in therapy of sensorineural hearing loss following war-related blast injury: retrospective study.

AIM: To establish whether a better recovery of the sensorineural hearing loss can be achieved by systemic administration of a vasodilator and vitamins in a saline infusion immediately after a blast injury. METHODS: Retrospective analysis included 134 patients with pure sensorineural hearing loss after blast injury (a total of 192 injuries), who were treated between 1991 and 1995. A group of 82 patients (119 injuries) was treated with 250 mL infusion of saline containing vitamins and pentoxifylin, whereas the other group (52 patients or 73 injuries) did not receive any therapy. RESULTS: The patients who received infusion therapy with vitamins and pentoxifylin showed no better hearing recovery than the patients who did not receive any therapy. There was no statistically significant difference between the groups in the average values of the sensorineural hearing recovery (p=0.315). CONCLUSION: Therapy with vitamins and pentoxifylin does not improve recovery of sensorineural hearing loss caused by blast injuries of the internal ear.

Blast Injuries↗

Autonomic dysfunction in patients with multiple sclerosis.

The disturbances of autonomic cardiovascular reflexes have already been described in patients with multiple sclerosis (MS). It seems that this disturbances are the result of reflex pathways impairment in the central nervous system. We have tested 28 patients with MS and control group of 21 healthy volunteers using a set of autonomic cardiovascular reflexes tests. In all of patients zones of demyelinization have been discovered with magnetic resonance imaging (MRI). The biggest number of abnormal results was found in respiratory sinus arrhythmia (RSA) test (60.7%) and cortical activation test (35.7%). In 11 patients we found abnormal results in 2 or more tests. Patients with abnormal results in 4 or more tests had clinical impairment of other autonomic functions (urinary bladder regulation). The results of autonomic dysfunction tests show positive correlation to the MRI findings.

Adult↗

Endonasal endoscopic dacryocystorhinostomy in a four-month-old infant.

The authors present a case of endonasal endoscopic dacryocystorhinostomy in a 4-month-old girl suffering from remarkable epiphora, persistent bulging and recurrent abscesses in the medial canthal region of the left eye. All conservative therapeutic attempts failed. Several external incisions were performed in order to solve the acute phases of the inflamed lacrimal sac. The procedure was performed by means of otologic microsurgical instruments under endoscopic control. No silicone stent was used. Ten months after surgery, the girl is doing very well.

Dacryocystorhinostomy↗