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Biomedical subjects

K Debnath

Publications and source records attributed to K Debnath.

5 recordsLinked to original sources
PubMedDate not supplied

Phaeochromocytoma at the root of the mesentery.

A 65-year-old male reported with a freely mobile abdominal lump and hypertension. Though pre-operatively and intra-operatively, we have suspected the lump to be a mesenteric cyst, postoperative histopathological examination revealed it to be phaeochromocytoma which is rare. In view of its extra-adrenal site of presentation and rarity, this case is reported herein.

Adrenal Gland Neoplasms↗
PubMedDate not supplied

Puetz-Jeghers syndrome involving appendix.

Puetz-Jegher's syndrome is an autosomal dominant hereditary disease, which is characterized by hamartomatous polyposis and mucocutaneous pigmentation mainly over the circum-oral region. Patients with Peutz-Jeghers syndrome seek medical attention whenever there are complications such as intussusception, bleeding from the polyps, etc. Occasionally, gastrointestinal tract malignancies have been reported in Peutz-Jeghers syndrome. In this paper, we report a patient with Peutz-Jeghers syndrome who had multiple complications and polyposis involving the appendix, because involvement of the appendix is extremely rare in Peutz-Jeghers syndrome.

Adolescent↗
PubMedDate not supplied

Colorectal cancer in younger patients.

Colorectal cancer is uncommon in India and particularly so in the younger age group below 40 years. The present study reports 18 patients with colorectal cancer between the age of 21 to 30 years. Rectum (n = 15, 83%) was the commonest site of the lesion and rectal bleed was the presenting feature in most (n = 16, 89%). Histopathologically, 9 (50%) had poorly differentiated adenocarcinoma. The tumor was unresectable in 5 patients (28%). Fourteen patients (78%) had advanced cancer indicated by TNM stage III or IV disease. Among the 13 patients subjected to surgical treatment followed by adjuvant chemotherapy, only 3 had long term disease free survival beyond 2 years. None of these patients had family history of colonic cancer or polyposis coli. In conclusion, colorectal cancer in younger age is not infrequent and had advanced stage at the time of clinical presentation with poor outcome.

Adenocarcinoma↗