PubMed Health⌕ Search

Biomedical subjects

K Dominiczak

Publications and source records attributed to K Dominiczak.

At least 19 recordsLinked to original sources
PubMed1981

Experimental atherosclerosis model in domestic pigs. Part II. Electrocardiographic and morphologic investigation.

Experimental atherosclerosis was produced in domestic pigs by administration for 24 weeks a high lipid diet containing cholesterol and coconut oil. ECG changes were not uniform: negative T, prolonged intraventricular conduction, and premature ventricular beats were observed. Macroscopic and microscopic anatomo-pathological studies revealed atheromatous changes in the aorta.

Animals↗
PubMed1979

Histologic changes in the spleen of rabbits following long-term and multiple immunization with sheep red blood cells.

Results of immunologic and histologic studies on rabbits immunized with sheep red blood cells (SRBC) showed dependence of the immunologic response (PFC, RFC) on the histologic structure of the spleen, particularly width of the sinusoidal vessels. Histologic changes in the spleen are a result of immunization and their intensity is related to the dose of antigen. The influence of dosage of antigen and histologic structure of the spleen on regulation of the immunologic response are discussed.

Animals↗
PubMed1977

[Effect of chronic action of cadmium sulfate on various biochemical indices of blood serum and on the histological picture of rat liver and kidneys].

Male rats weighing 180-220 g were given CdSO4, 0,4 mg/kg body weight subcutaneously once a week for 6-12 months. The animals were killed after 6, 9, 12 months and following blood serum levels were determined: total protein, albumin, globulin, GPT, GOT, Al.P. and urea. The tissue tissue samples from liver and kidneys were examined histologically (acid and alkaline phosphatase). After 9 months, the difference between values of biochemical indices in the exposed and control groups was statistically significant. It has been found that the observed biochemical indices show correlation with the extent of morphological changes in liver and kidneys. These degenerative changes became more intense in the liver than in the kidneys.

Animals↗