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Biomedical subjects

K Dvorák

Publications and source records attributed to K Dvorák.

At least 19 recordsLinked to original sources
PubMed1992

[Distribution of periventricular necrosis and mild pathomorphologic changes in the brain in hypoxic-ischemic encephalopathy in neonates].

An analysis of histotopographic sections from 31 neonatal brains with hypoxic periventricular necroses. Distribution and topography of necroses was traced in 7 frontal planes in correlation to frequency of impaired white matter tracts. Results were summarized in schemes. Another topic of analysis was morphology of a slight white matter impairment (spongiosis). Used three grade classification of slight white matter impairment contributed to morphologic criteria of neonatal hypoxic-ischemic encephalopathy. Having considered his own findings and data from literature the author decided a standard histological tissue sampling for perinatal encephalopathies.

Brain↗
PubMed1990

[A database for registration of biopsy findings].

Description of a database system for registration of biopsies in a IBM-PC (AT) compatible computer. The system enables simple registration of bioptic findings for needs of diagnosis, teaching, seminars, and research.

Biopsy↗
PubMed1990

[Intravenous systemic thrombolysis using streptokinase in the treatment of developing cardiogenic shock in myocardial infarct].

The author evaluated retrospectively the therapeutic effect of intravenous systemic thrombolysis by streptokinase in 24 patients with developing cardiogenic shock associated with myocardial infarction. Fourteen patients died while in hospital (58%) and 10 (42%) survived and were discharged after a suitable time in hospital. Serious arrhythmias were frequent already before thrombolysis (ventricular fibrillation 2X, AV block grade II and III 5X, atrial fibrillation 4X). After streptokinase administration in two patients ventricular tachycardia was recorded, twice significant ventricular extrasystoles and once AV block grade II. In none of the patients arrhythmia was the cause of death. No allergic reaction was recorded. One patient following cardiopulmonary resuscitation developed after thrombolysis haemorrhage into the chest wall from the site of injection into the subclavian vein, without further sequelae. Thirteen of the dead were subjected to necropsy which confirmed the clinical diagnosis: once a haemorrhagic infarction was found, once rupture of the heart with tamponade. In two instances coronary thrombosis was detected. Of the 10 discharged patients at the end of 1988 seven patients survived for a period of 1-8 years. From the described group it may be concluded that systemic thrombolysis in patients with developing cardiogenic shock associated with myocardial infarction is not associated with a higher incidence of side-effects and that in some of the patients with a very adverse prognosis, after streptokinase administration a change in the course of the disease occurred leading to improvement of the condition and discharge from hospital.

Aged↗
PubMed1989

[Traumatic ruptures of the diaphragm].

The authors present a group of three traumatic ruptures of the diaphragm and call attention to the possibility of this injury in blunt injuries of the chest or abdomen. In the diagnostic part they describe the complex character of diagnosis of rupture of the diaphragm even when modern non-invasive examination methods are used, some of which (CT) may give false positive results. The authors describe typical symptoms leading to the diagnosis.

Accidents, Traffic↗
PubMed1989

[Cardio-pulmo-cerebral resuscitation in myocardial infarct in the emergency medical service].

Of 1234 patients with confirmed myocardial infarction who were treated at the emergency medical service station in Ostrava in 95 (8%) circulatory arrest developed and cardiopulmocerebral resuscitation was applied. In 60 (63%) it was not possible to restore spontaneous circulation and they were subjected to necropsy after resuscitation efforts. A total of 35 (37%) of the resuscitated patients were taken to hospital. Resuscitation was permanently successful in 19 (20%) of patients with myocardial infarction. The authors discuss the most frequent shortcomings of urgent resuscitation as well as other possible ways how to improve the final results.

Heart Arrest↗
PubMed1988

Autolyzed antigen-extracted allogeneic bone for bridging segmented diaphyseal bone defects in rabbits.

The autolyzed antigen-extracted allogeneic (AAA) bone implant was placed into a 17-mm long diaphyseal periosteum-free defect in the radius in 27 rabbits. The animals were observed physically and roentgenologically every week. The continuity of the radius was evaluated macroscopically and histologically. Maximum length of the follow-up period was 114 days. The AAA implants were progressively resorbed and replaced by the recipient's bone growing from fragments of radius, restoring the continuity of diaphysis. Osteoinductive activity of the implant was transferred across a tube of a polyamide vascular prosthesis. There were no appreciable histologic signs or immune of foreign-body reaction.

Animals↗
PubMed1985

[Hypoxic changes in the germinative subventricular layer of the brain in neonates].

The subventricular layer changes were studied in 125 brains of neonates weighing 800-3 500 g. A hypoxic encephalopathy without haemorrhage was found in 35% (basic group), negative finding was in 40% (control group); cases with ventricular and periventricular haematomas (24%) were omitted. In the basic group, 47% of cases showed subventricular layer changes. The changes occurring always combined with a hypoxic lesion of the white matter are to be taken for hypoxic ones as well. The changes were evaluated and classified into 4 descriptive findings. Cytoplasmic swelling of astroglia, rarefaction and focal as well as big irregular necroses of the subventricular layer. Acute hypoxic subventricular layer changes were discussed in connection with residual states.

Cerebral Hemorrhage↗