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Biomedical subjects

K E Elizabeth

Publications and source records attributed to K E Elizabeth.

13 recordsLinked to original sources
PubMed2006

Mid arm circumference (MAC) and body mass index (BMI)--the two important auxologic parameters in neonates.

Even though birth weight is the most sensitive predictor of health and outcome, accurate weighing and proper recording are not done in most developing countries. Most neonates lose 10% of body weight soon after birth and when such babies subsequently come for medical care, it becomes difficult to know whether the baby was low birth weight (LBW) at birth or not, to predict the outcome. Among the many surrogate auxologic parameters to identify LBW babies, mid arm circumference (MAC) was found to be the most useful and simplest. At a cut off of 9 cm, with a sensitivity of 92% and a specificity of 90.5% to identify LBW, MAC is recommended as an alternative measurement. Ponderal index is measured in neonatal period to identify growth retardation. Body mass index (BMI) is a very useful index in children and adults to identify obesity/chronic energy deficiency (CED). Tracking of BMI from neonatal period to adulthood is recommended to plan intervention and predict outcome. The mean BMI observed in the present study was 12.86 kg/m2 close to the expected of 13.

Anthropometry↗
PubMed2003

Three-in-one weight, height and body mass index charts for children and adults.

The aim of the study was to develop four appropriate three-in-one weight, height and built in body mass index (BMI) charts, for under-fives, 0-5-year-olds, > 5-10-year-olds, > 10-18-year-olds, and adults and to delineate the normal range, underweight, overweight and obesity on the above charts. Four different charts were designed for the various age groups as indicated above. Height was made available on the x-axis, weight on the y-axis, and corresponding BMI values on the right margin. Shading of the normal range to denote the health path and marking of the cut-off curves to denote normal status, overweight, and obesity were done selecting appropriate round figures to suit both sexes in accordance with the International Obesity Task Force (IOTF) recommendations for the various age groups. Field trials were done on appropriate subjects belonging to various age groups. 500 in each group with equal male to female ratio. The field trials showed that all the studied subjects belonging to both sexes came within the purview of the chart and those with normal nutritional status, underweight, overweight, and obesity could easily be identified looking at the chart without doing any further calculation. Early intervention also could be advised as the chart could demonstrate how much weight should be gained or reduced to come within the health path. In conclusion, the charts are applicable to both sexes and are user friendly. These are appropriate for general screening of nutritional status and to determine underweight, overweight, and obesity from birth to adulthood. They give a visual display of the ideal health path with respect to weight, height, and BMI and the adjustment in weight required to reach the normal range.

Adolescent↗
PubMed2003

Correlation of age and birth order of parents with chromosomal anomalies in children.

One hundred children with suspected congenital and/or malformation and their parents who reported to SAT hospital, Medical College, Trivandrum, India formed the test group. Fifty children with no obvious anomalies or abnormalities and their parents formed the control group. The criteria for selection of the control was 1) the maternal age at delivery was below 30 years and 2) the parents belong to 1st or 2nd birth order. The chromosomal analysis was carried out in all the subjects using peripheral blood lymphocyte microculture to investigate for any constitutional chromosomal markers and quantitate the mutagen (bleomycin) sensitivity of the chromosomes. All the subjects were evaluated clinically and a complete family history was recorded. Chromosome anomalies were noted in 41 out of the one hundred children and in 4 out of the 200 parents of the test group. No constitutional aberrations were seen either in the parents or in the children of the control group. Bleomycin sensitivity study revealed a high b/c value in 35 children (24 hypersensitive and 11 sensitive) of the test group whereas in the control group the b/c values were low denoting hyposensitivity and very good DNA repair mechanism. This study reveals that the incidence of chromosome aberrations is higher when the age and birth order of parents are higher. A direct correlation was noted with parental order and b/c value. This was also true with the parental age and birth defects.

Abnormalities, Multiple↗
PubMed1997

The role of developmental stimulation in nutritional rehabilitation.

OBJECTIVE: To evaluate the role of developmental stimulation and nutritional supplementation in rehabilitation of malnourished children in the hospital and community settings. DESIGN: Prospective follow up study. SETTINGS: (i) Nutrition clinic of a teaching hospital; and (ii) Community Nutrition Project in coastal Kerala. SUBJECTS: (i) Hospital study: 100 children aged 6-24 months with moderate and severe Protein Energy Malnutrition (PEM) constituted the study group. The control group consisted of well nourished children matched for age and sex, 50 from high (Control I) and 50 from low socioeconomic (SE) status (Control II). The study group was randomized into two subgroups to administer the interventions namely composite stimulation package (STIM) or nutritional management (NUT). (ii) COMMUNITY STUDY: A cohort of 332 children aged 6-24 months with varying grades of PEM were studied. As per the area of residence, they were divided into three subgroups; 2 study groups to administer the two interventions namely STIM or NUT and a control group. METHODS: In both the hospital and community studies, environmental parameters, growth and development were assessed initially. After two years, the study groups were reassessed in comparison with the control groups. A final IQ assessment was done in each subgroup by a tester blinded to the grouping. RESULTS: (i) Hospital study: Control children from high SE status (Control I) had the highest overall scores compared to those from low SE status (Control II) as well as the study groups with PEM even after administering either STIM or NUT. Both the interventions produced a significant positive impact on growth and development, but STIM was found superior to NUT. (ii) Community study: There was a high prevalence of PEM in the community, which reduced significantly after the interventions. STIM was found superior in its positive impact on growth and development. In both studies, direct correlation was observed between environmental parameters and anthropometric scores and between anthropometric scores and IQ. CONCLUSIONS: The benefit of developmental stimulation in nutritional rehabilitation and the need for providing better environment for deprived children are brought out in this study.

Analysis of Variance↗
PubMed1997

Antipyretic therapy.

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Anti-Inflammatory Agents, Non-Steroidal↗
PubMed1991

Growth faltering and developmental delay in children with PEM.

Anthropometric measurements, Somatic Quotient (SQ), Development Quotient (DQ), Motor Quotient (MoQ) and Mental Quotient (MeQ) in 136 children in the age group 1-24 months with varying degrees of protein energy malnutrition (PEM) were compared with an equal number of comparable well nourished children. There was a progressive reduction in SQ, DQ, MoQ and MeQ as the degree of PEM advanced. There was a direct linear correlation between SQ and DQ and between height and DQ in 4 degrees PEM. However, there was no direct correlation between head circumference and either DQ or MeQ.

Body Height↗