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Biomedical subjects

K E Karlson

Publications and source records attributed to K E Karlson.

69 records · Page 4Linked to original sources
PubMedDate not supplied

Successful correlation of type C complete atrio-ventricular (A-V) canal in infancy.

Herein, a successful repair of Type C complete A-V canal in infancy is reported. With a better understanding of anatomy as well as improved perioperative care it appears the primary repair is more reasonable approach than the high risk palliative operation (pulmonary artery banding), when surgery is required in such disease.

Down Syndrome↗
PubMedDate not supplied

Initial clinical experience with a more efficient hollow fiber oxygenator of unique design.

The first 90 cardiac surgery cases perfused with a new hollow fiber membrane oxygenator in which the gas flows through the fibers and blood flows around the fibers are reported. The fibers are microporous polypropylene with a pore size of 0.03 microns. Membrane surface area is 2.0 M2 and priming volume is 480 ml, including heat exchanger PaO2 is controlled by FIO2 and PaCO2 by gas flow rate. Patients as large as 2.36 M2 were perfused up to 348 min using hemodilution and hypothermia. The mean PaO2 was 200 mmHg and the mean PaCO2 39.5 mmHg. Oxygen transfer was as high as 230 ml/min. This low prime device transfers large volumes of gas, an efficiency which results from a crossed arrangement of the fibers to break up laminar flow of the blood around them. The low priming volume makes it appropriate for use in all but the smallest patients.

Adult↗
PubMedDate not supplied

Clinical evaluation of the interpulse low resistance microporous membrane oxygenator.

The Interpulse microporous membrane oxygenator has been used in 100 patients for cardiac surgery. This oxygenator features transverse furrows in the membrane and a back and forth motion of the blood as it flows between the membranes. This pulsing motion causes secondary flows or vortices to occur in the furrows of the membrane. These secondary flows promote mixing of the blood in the film. This oxygenator has been used in a single pump circuit for perfusions for up to 343 minutes at a flow rate up to 5.9 l/min. Oxygen saturation has always been 98% or greater. The pulser rate of the oxygenator influences oxygen transfer, and the pulser rate has been regulated between 80 and 225 pulses per minute to achieve a mean arterial PaO2 of 207 mmHg. Carbon dioxide transfer is affected by the oxygen flow through the device and has been adjusted to between 0.2 and 7 l/min to obtain a mean PaCO2 of 40 mmHg in this series. This device has proved to be safe and effective in perfusions for cardiac surgery.

Adolescent↗
PubMedDate not supplied

Clinical evaluation of a microporous membrane oxygenator.

1. The microporous membrane oxygenator has a maximum priming volume of 400 ml. and transfers up to 250 ml. of O2. 2. CO2 transfer is excessive when ventilating the oxygenator with 100% O2. CO2 should be added to the ventilating gas. 3. The oxygenator has performed satisfactorily in 90 cases of cardiac surgery with perfusion time up to nine hours. 4. Precautions are described to prevent possible accumulation of water vapor in the oxygenator.

Adolescent↗