President's message. Nurses make a positive impact on patient care: here's the proof!
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Biomedical subjects
Publications and source records attributed to K E Schardin.
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Chronic anemia frequently causes changes in cardiac function, particularly left ventricular function, that can lead to serious cardiovascular problems. Because Epoetin alfa corrects anemia, it may eliminate some of these problems or decrease their severity. By assessing cardiovascular function and monitoring response to Epoetin alfa, nurses can help patients achieve their optimal level of cardiac function.
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Nursing management of anemic dialysis patients requires a thorough understanding of the conditions that can potentially affect erythropoiesis. Erythropoietin deficiency has been documented as the primary cause of the anemia of uremia, and Epoetin alfa has proven to be an effective therapy for correcting this condition. However, other etiologies, independent of the uremic process, can also contribute to anemia in these patients and lead to a diminished response to Epoetin alfa. Iron deficiency and blood loss, for example, are well-documented etiologies that can hinder erythropoiesis and diminish the response to Epoetin alfa (Van Wyck, 1989). Another etiology still under investigation is the potential effect of infection or inflammation on the response to Epoetin alfa. This article examines the anemia of infection and inflammation and the potential effect on response to Epoetin alfa.
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