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Biomedical subjects

K Ettler

Publications and source records attributed to K Ettler.

14 recordsLinked to original sources
PubMed1998

[Determination of the minimal erythema dosage and natural photoprotection of the skin in the population].

Effects of ultraviolet radiation (UV) on the human skin are summarized in the introductory part from physical and biological point of view, especially photoaging and photocarcinogenesis. Special attention has been paid to skin phototype which characterizes the individual susceptibility to UV. The minimal erythema dose (MED) serves for establishment of this susceptibility. The mean MEDs for white population in other countries are also shown here. Mechanisms of natural photoprotection in connection with instructions how to increase artificial photoprotection are described here. The investigation of skin type incidence in our population and determining their mean MEDs for UV-B and polychromatic light was the aim of practical work. The UV-B MED is in average 23.4 mJ/cm2. The further work has been concentrated on the assessment of pigmentation response after irradiation and especially on the comparison of the minimal erythema doses before season and after it. We found mean double increase of the MED after sunlight exposition during summer season. We suggested, that double increasing of seasonal natural photoprotection does not represent definitive protection for most people and does not impair summer warning system in media which is based on winter MEDs. Some recommendations for improvement of protection of Czech population against UV radiation are proposed in conclusion.

Adolescent↗
PubMed1993

[Malignant melanoma of the head and neck].

The authors evaluate the group of 25 patients suffering from malignant melanoma in head and neck region. Patients were treated on ENT clinic in Hradec Králové during 1961-1991. The authors describe the localization of malignant melanoma, the process of therapy and the surviving of patients. The contemporary opinions are discussed for possibilities of therapy.

Adult↗
PubMed1993

[The adverse effects of computer video monitors on their operators].

Probable undesirable influence of visual display terminals to attendance are characterized: electric and electrostatic fields, magnetic field, x-ray and UV-radiation. There are described protective arrangements here: terminals of a new construction, prospectively protective filters in front of old terminals.

Computer Terminals↗
PubMed1993

Skin side-effects of amiodarone therapy.

Amiodarone is a antiarrhythmic drug with many side-effects which include also the induction of photosensitivity and the development of greyish-blue pigmentations on the skin exposed to light. The authors examined 64 patients treated with amiodarone and 32 controls by means of a phototest using a xenon lamp. In 9.4% photosensitivity was recorded, in 9.4% there were greyish-blue hyperpigmentations in the face and on the back of the hands. Histological identification of these hyperpigmentations including electron microscopy was also performed.

Adult↗
PubMed1992

[The role of ultraviolet rays in the etiopathogenesis of malignant melanoma].

The aim of the study was to elucidate the role of UV radiation in the etiology of malignant melanoma within the conditions of East Bohemia region. In selected patients with malignant melanoma, anamnestic data pertinent to the frequency of sun-bathing as well as a bulk of the occupational indoor exposures brought about the action of UV-light artificial sources have been withdrawn from past history. Constitutional features for suspected photosensitivity such as the fair skin complexion and skin phototype, were investigated. The object of assumption was also the site of anatomical localization (i. e. body site distribution) of primary malignant melanoma. In a selected group of patients, routine phototesting followed by the above-threshold skin phototests were carried out with the aim to assess the capacity of reparative processes essentially occurring in the irradiated skin. In the epidemiologically oriented part of study, presumable relationships between the year's maxima of sunlight radiation and the increases in the incidence of malignant melanoma were treated statistically. It followed from the results obtained that sunlight itself is not a decisive factor and cannot explain an increased incidence of malignant melanoma in East Bohemia region.

Animals↗
PubMed1990

Polymorphous light eruption: PUVA-induced skin hyporeactivity.

Eight patients with polymorphous light eruption (PLE) were treated with the 8-methoxypsoralen (0.6 mg/kg) and UV-A given in an ordinary PUVA cabin. Excellent or good results were observed in 4 and moderate in others remained patients. It is concluded that PUVA treatment is a safe form of therapy which exercises its beneficial effect in the patients with PLE. Various theories concerning the mode of action of photochemotherapy in PLE are discussed in this paper.

Adult↗
PubMed1990

[Skin diseases in computer terminal operators].

Authors describe two cases of computer operators (female subjects) which experienced face skin disorders in connection with computer's terminal staffing. The first case was concerned with acute worsening of seborrheic dermatitis, the second one with photosensitive reaction complicated partially by psychogenic erythema.

Adult↗
PubMed1989

Photoprotective adaptation in polymorphic light eruption.

Six patients with polymorphic light eruption were treated with ultraviolet light A (UV-A) for 1-2 months during the spring of 1984 and a follow-up study was carried-out in September 1984. The PLE patients with an UVA - induced skin pigmentation became clearly better or got rid of their symptoms more often than those with "non-adapted" pale skin condition. The good results achieved during and after UV-A phototherapy held during the summer but were lost during the winter. Therefore it became necessary to repeat the photoprotective adaptation each spring.

Adult↗