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Biomedical subjects

K F Bowman

Publications and source records attributed to K F Bowman.

At least 19 recordsLinked to original sources
PubMed2000

Mesenteric rents as a source of small intestinal strangulation in horses: 15 cases (1990-1997).

OBJECTIVE: To describe the clinical findings in horses with small intestinal strangulation through mesenteric rents, and to determine the recurrence and survival rates after surgery. DESIGN: Retrospective study. ANIMALS: 15 horses with small intestinal obstruction via a mesenteric rent. PROCEDURE: Medical records of horses with obstruction of the small intestine via a mesenteric rent between January 1990 and December 1997 were reviewed. The signalment, history, initial physical examination findings, results of abdominocentesis, and clinical laboratory values were recorded. Surgical findings, including location of the mesenteric rent and surgical procedure performed, were recorded. Short- and long-term survival rates were calculated. RESULTS: Most mesenteric rents were located in the mesentery of the small intestine (13 horses). Two horses had multiple mesenteric defects. Seven horses were euthanatized at surgery because of an inability to reduce the entrapped intestine (3 horses), uncontrollable hemorrhage (2), inability to close the rent (1), and the amount of compromised intestine involved (1). Seven horses required intestinal resection and anastomosis. The median length of intestine resected was 2.6 m (range, 0.6 to 4.5 m). The mesenteric rents created during resection were not closed in 2 horses. One of these 2 horses subsequently developed a strangulating obstruction through the open rent. Seven of 15 horses in our study were discharged from the hospital (i.e., short-term survival rate of 47% [7/15]). Long-term follow-up information was available for 5 of the 7 horses (follow-up duration of 5 months to 9 years), of which 2 died as a result of colic, and 1 horse was euthanatized because of severe arthritis (i.e., long-term survival rate of 40% [2/5]). CONCLUSIONS AND CLINICAL RELEVANCE: Inability to reduce the intestinal obstruction, severe hemorrhage from the mesentery, and the length of intestine involved are the main factors that decrease survival rates in horses with small intestinal strangulation caused by mesenteric rents.

Animals↗
PubMed2000

Nurse versus family caregiver perspectives on hospitalized older patients: an exploratory study of agreement at admission and discharge.

Staff nurses and family caregivers of hospitalized elderly patients (> or = age 70) play crucial roles in the health care and recovery of patients. This exploratory study identified and compared nurse and family caregiver perceptions about the patient's health condition, needs to stay healthy, and problems in self-care at admission and discharge. Agreement between nurse and caregiver reports at both time points was assessed. Overall, findings confirmed a lack of agreement between nurses and family caregivers. At both time points, fewer nurses than caregivers focused on disease in describing the patients' health condition, and there was low agreement about diseases when mentioned. Although the great majority of nurses and caregivers reported one or more patient needs to stay healthy, and problems with self-care, there was little agreement about specific needs or problems mentioned at either time point. Findings may be attributed, in part, to current limitations on staff nurses' bedside time or insufficient opportunities, skills, or both to communicate with families about patients as part of comprehensive discharge planning. Organizational factors in large tertiary care hospitals may serve as a deterrent to nurse-family caregiver contact and communication during hospitalization.

Adult↗
PubMed1999

Diagnosis and surgical treatment of periapical infection of the third mandibular molar in five horses.

Diagnosis and treatment of periapical infection of the third mandibular molar in 5 horses was assessed. In 4 of 5 horses, there was a recent history of dental work performed. Diagnosis required multiple imaging techniques. Radiography revealed evidence of periapical bone lysis or tooth root lysis of the third mandibular molar in 3 of 5 horses. Sonographic examination was effective in identifying abscesses within the masseter muscle and defects of the lateral cortex of the mandible in 4 of 5 horses. Nuclear scintigraphy was diagnostic in 1 of 2 horses examined. All horses were treated by repulsion of the affected tooth. The surgical approach involved elevating the masseter muscle from the caudal portion of the mandible. This approach provided excellent access to the affected tooth with minimal postoperative complications. All incisions healed with good cosmetic results.

Animals↗
PubMed1998

Endoscopic treatment of suspected infectious intertubercular bursitis in a horse.

A 9-year-old gelding was evaluated because of a 30-day history of mild intermittent left forelimb lameness. The only detectable abnormality was mild atrophy of the musculature of the proximal portion of the left forelimb. The cause of the lameness could not be determined. The horse was discharged from the hospital, but was reexamined 6 weeks later because of worsening of the lameness. At that time, the horse resisted flexion and extension of the left shoulder joint, and results of evaluation of an ultrasound-guided aspirate of fluid from the intertubercular bursa were suggestive of infection. Endoscopic examination of the bicipital bursa revealed synovial hypertrophy, particularly in the distal aspect of the bursa. The bursa was lavaged, and a synovial resector was used to remove inflamed synovium. The horse recovered and was healthy 4 months later. In this horse, endoscopy allowed adequate examination of the intertubercular bursa and was not technically difficult.

Animals↗
PubMed1998

Cutaneous lymphoma with extensive periarticular involvement in a horse.

Two months after colic surgery, subcutaneous masses were found on the ventral and lateral portions of the thorax of a 3-year-old Hanoverian-cross filly. Six months later, the filly was admitted for evaluation of severe lameness. Arthrocentesis of the tarsocrural joint yielded clotted sanguineous material; however, unusual multinucleated giant cells were seen. Radiography of the right tarsus revealed soft tissue opacity and degenerative joint disease. The filly was euthanatized to prevent further suffering. At necropsy, multiple soft-tissue masses were located throughout the fascial planes of the tarsi and in the subcutis of the ventral and lateral portions of the thorax. Neoplasms consisted primarily of a large number of mature well-differentiated T lymphocytes. On the basis of these findings, the diagnosis was cutaneous lymphoma with unusual involvement of periarticular tissues. Severe degenerative joint disease in the right tarsus did not appear to be associated with the tumors.

Animals↗
PubMed1998

Family caregiving of hospitalized patients. Caregiver and nurse perceptions at admission and discharge.

To ensure patients will be discharged to stable, health-promoting home environments, nurses must understand family caregivers' perceptions of the patients' needs and problems in caring for them. At the time patients were admitted to and discharged from the hospital, there was little agreement between family caregivers and nurses about the kinds of things caregivers needed to care for older patients or about problems that might prevent the continuation of caregiving. There was slightly more overall agreement between family care-givers and admission nurses than discharge nurses, despite the fact that discharge nurses reported spending more time with patients and being more knowledgeable about them. Future discharge planning models should build opportunities for nurses to communicate with other health care colleagues who can contribute to a more accurate and complete picture of patients' and family caregivers' needs and problems in the transition from hospital to home.

Adult↗
PubMed1997

Pharmacokinetics of cisapride in horses after intravenous and rectal administration.

OBJECTIVES: To determine the i.v. pharmacokinetics of cisapride and measure systemic absorption after rectal administration. ANIMALS: 5 healthy adult mares (380 to 610 kg). PROCEDURE: Cisapride was administered, i.v., at a dosage of 0.1 mg/kg of body weight. In the same horses, after a 1-week washout period, cisapride was administered rectally at a dosage of 1 mg/kg by mixing crushed tablets with propylene glycol and administering the mixture into the rectum. After each drug administration, a series of blood samples were collected. Plasma was obtained and analyzed by high-performance liquid chromatography to determine cisapride concentration profiles after each drug administration. RESULTS: After i.v. administration, peak plasma concentration was 221.4 ng/ml and harmonic mean half-life was 1.9 hours. Rectal absorption of cisapride was negligible. Cisapride was detected in plasma from only 3 of 5 horses for which mean systemic availability was 1.23%. Mean maximal plasma concentration after rectal administration of cisapride was 13.5 ng/ml. CONCLUSION AND CLINICAL RELEVANCE: After i.v. administration of cisapride, plasma concentration is high for approximately 2 hours. Cisapride mixed with propylene glycol and administered rectally at a dosage of 1 mg/kg is poorly and incompletely absorbed. Thus, cisapride is not clinically useful for rectal administration in horses.

Absorption↗
PubMed1996

Jejunocolostomy or ileocolostomy for treatment of cecal impaction in horses: nine cases (1985-1995).

OBJECTIVE: To determine whether complete cecal bypass, by jejunocolostomy or ileocolostomy, is an effective treatment for horses with cecal impaction. DESIGN: Retrospective analysis of medical records. ANIMALS: 9 horses with cecal impaction managed by jejunocolostomy (3) or ileocolostomy (6) performed with or without typhlotomy for evacuation of cecal contents. PROCEDURE: Information on age, breed, gender, duration of medical treatment, preoperative abnormalities, surgical procedure, and postoperative complications was retrieved from the medical records. Follow-up data were obtained via telephone interview with owners. RESULTS: 6 males and 3 females between 9 and 24 years old (median, 14 years) were included. Five of 9 horses had signs of mild pain associated with reintroduction of food after surgery. All 7 horses for which follow-up information was available were still alive between 7 and 54 months (median, 1.5 years) after surgery. CLINICAL IMPLICATIONS: Jejunocolostomy or ileocolostomy resulted in apparently permanent resolution of cecal impaction in these horses and acceptable long-term outcomes. Mild signs of abdominal pain associated with the onset of feeding can be expected in the early postoperative period.

Anastomosis, Surgical↗
PubMed1995

Loop colostomy for treatment of grade-3 rectal tears in horses: seven cases (1983-1994)

OBJECTIVE: To determine the feasibility of performing a single-incision loop colostomy for treatment of grade-3 rectal tears in horses. DESIGN: Retrospective case series. ANIMALS: Seven adult horses with grade-3 rectal tears. PROCEDURE: A single-incision loop colostomy was performed with horses under general anesthesia (n = 6) or while restrained in standing stocks (n = 1). The rectal tear was lavaged via an endoscope. The colostomy was resected after the rectal tear healed. RESULTS: Rectal tears ranged from 4 to 10 cm in diameter and were > 25 cm proximal to the anus. All horses survived colostomy surgery. One horse was euthanatized at the request of the owner 1 day after surgery. Six horses underwent colostomy resection 13 to 30 days after colostomy. All horses had evidence of atrophy of the distal portion of the small colon, predisposing to impaction at the small colon anastomosis in 2 horses. One horse was euthanatized while hospitalized because of severe recurrent colic. Five horses were discharged from the hospital 31 to 45 days after admission. One horse was euthanatized 60 months after discharge from the hospital because of severe colic, and 4 horses were alive at the time of follow-up evaluation (3 to 12 months after discharge). CLINICAL IMPLICATIONS: The prognosis for horses with grade-3 rectal tears treated by colostomy appears to be favorable.

Animals↗
PubMed1994

Evaluation of factors associated with postoperative ileus in horses: 31 cases (1990-1992)

Medical records of horses that underwent surgical treatment for colic between 1990 and 1992 were reviewed. Horses with a pulse rate of > or = 60 beats/min or signs of abdominal pain, which were also accompanied by a volume of > 2 L of material that refluxed from the stomach during the postoperative period (excluding horses with anterior enteritis), comprised the postoperative ileus (POI) group. Horses that had < 2 L of material reflux during the postoperative period and survived > 3 days after surgery comprised the reference population. The association of preoperative and intraoperative clinical variables with development of POI was evaluated by use of logistic regression analysis. Of 148 horses, 117 were assigned to the reference population, and 31 (21%) developed POI. Multiple logistic regression analysis was used to determine that PCV, pulse rate, type and location of lesion detected during surgery, and serum glucose concentration were the most important variables associated with development of POI. Time of recovery from anesthesia to development of POI was 0.5 to 120 hours (median, 13 hours). Duration of POI was 1 to 7 days (median, 1 day). Four of 31 (13%) horses with POI died. Of 148 horses, only 10 (7%) died; however, 4 of the 10 (40%) deaths in the short-term postoperative period were attributable to POI.

Animals↗
PubMed1994

Holding power of orthopedic screws in the large metacarpal and metatarsal bones of calves.

Holding power was determined for various orthopedic screws in bones of calves. Holding power was defined as maximal tensile force required to remove a screw divided by thickness of bone engaged by the screw (kN/mm). Comparative pull-out tests were performed, using pairs of large metacarpal or metatarsal bones from calves aged 3 to 14 days. Comparisons were made of the holding power of 6.5-mm fully threaded cancellous screws and 5.5-mm cortical screws in the proximal and distal metaphyses, and of 4.5-mm and 5.5-mm cortical screws in the diaphysis. Sixteen repetitions of each comparative trial were performed. There was no statistically significant difference in the holding power of 4.5- and 5.5-mm cortical screws in the diaphysis. There was no significant difference in the holding power of 5.5-mm cortical and 6.5-mm fully threaded cancellous screws in the proximal metaphysis. In the distal metaphysis, 6.5-mm fully threaded cancellous screws had significantly (P < 0.001) greater holding power than did 5.5-mm cortical screws. There was no significant difference between the mean holding power of 5.5-mm cortical screws in the proximal metaphysis and 5.5-mm cortical screws in the distal metaphysis. There was significantly (P < 0.01) greater mean holding power of 6.5-mm cortical, fully threaded cancellous screws in the distal metaphysis, compared with the proximal metaphysis.

Animals↗
PubMed1993

Peritonitis in horses: 67 cases (1985-1990).

Peritonitis was diagnosed in 67 horses between 1985 and 1990: 14 horses developed septic peritonitis after intestinal rupture, 25 horses developed peritonitis after abdominal surgery, and 28 horses had peritonitis not associated with intestinal rupture or abdominal surgery. Forty of 67 horses (59.7%) did not survive. Nonsurvivors had higher heart rates (P = 0.01), RBC count (P = 0.039), serum creatinine concentration (P = 0.036), PCV (P = 0.007), and anion gap (P = 0.005); lower venous blood pH (P = 0.002); and a greater number of bacterial species cultured from peritoneal fluid samples (P = 0.054), compared with those from survivors. Nonsurvivors were more likely to have signs of abdominal pain (P < 0.000), circulatory shock (P = 0.009), and bacteria in peritoneal fluid samples (P = 0.042). Physical examination and peritoneal fluid analysis were the most valuable diagnostic aids for intestinal rupture. Peritonitis after abdominal surgery resulted in high mortality (56%); peritonitis not associated with intestinal rupture or abdominal surgery had lower mortality (42.9%). Clinical and laboratory indices can be of value in determining the prognosis for horses with peritonitis.

Animals↗
PubMed1993

Surgical management of urolithiasis in small ruminants.

Twenty-one cases of urolithiasis in small ruminants were examined to evaluate the efficacy of various surgical treatments. Of 21 cases, all but 1 had multiple calculi. Urethral process amputation and medical therapy either did not relieve the obstruction or provided only temporary relief (< 36 hours) in 14 of 16 cases. In 2 cases, obstruction recurred in 1 year and 4 years, respectively, after urethral process amputation. Ten of 13 animals that had perineal urethrostomy (PU) experienced short-term complications, including postoperative hemorrhage, dehiscence of the surgical wound, and subcutaneous accumulation of urine. Urethral stricture occurred in 7 of 9 animals in which follow-up information was obtained, and long-term survival was 55%. Cystotomy alone was performed on 8 of 21 cases, and 7 of 8 (88%) were healthy at the time of follow-up. In order to relieve the obstruction with cystotomy alone, multiple attempts at normograde and retrograde flushing were required. Cystotomy allowed removal of multiple calculi, bidirectional flushing of the urethra, and posed less risk for short-term postoperative complications and urethral stricture. These data suggest that cystotomy was more effective than PU for the management of urolithiasis in small ruminants.

Animals↗
PubMed1992

Excision of the distal sesamoid bone for treatment of infection of the digit in a heifer.

An 8-month-old Holstein heifer was evaluated for right hind limb lameness of 3 weeks' duration. Diagnoses were osteomyelitis and fracture of the distal sesamoid bone, septic arthritis of the distal interphalangeal joint, and osteomyelitis of the third phalanx. After excision of a section of tissue from the plantar aspect of the digit and partial section of the deep digital flexor tendon, the distal sesamoid bone was excised. The third phalanx was curetted, and the surgical wound was lavaged. Twenty months after surgery, the heifer was fully weightbearing on the affected digit. Surgical exploration of the digit should be considered an alternative to claw amputation in cattle that have severe digital infections.

Animals↗
PubMed1992

Pedunculated lipomas as a cause of intestinal obstruction in horses: 17 cases (1983-1990).

The medical records of 17 horses that were evaluated and treated because of colic caused by pedunculated lipomas between 1983 and 1990 were reviewed. The mean age of the horses was 16.6 +/- 3.9 years (range, 10 to 26 years), which was significantly greater than that of the population of horses evaluated because of colic (control population) during the same period. There were significantly more geldings (76.5%), compared with the control population. Nasogastric reflux ranged from 1 to 16 L in 8 horses and was not obtained in 9 horses. Abdominal palpation per rectum revealed small intestinal distention in 13 horses, displaced large colon in 7 horses, and large colon impaction in 2 horses. Peritoneal fluid was abnormal in 11 of 12 horses from which it was obtained successfully. One horse was euthanatized after unsuccessful medical treatment. Surgery was performed in 16 horses. Lipomas were blindly resected in 5 horses or exteriorized and resected in 6 horses. The method used to resect the lipoma was not recorded in 5 horses. The ileum and/or jejunum was strangulated in 15 horses, the small colon was strangulated in 1 horse, and the jejunum was obstructed in 1 horse. The length of intestine resected ranged from 0.15 to 7.2 m. Fourteen horses survived surgery, of which 11 were discharged from the hospital (short-term survival rate of 78.6%). Excluding 2 horses lost to follow-up evaluation, 6 of 12 horses that survived surgery were alive 2 to 56 months following surgery (long-term survival rate of 50%), and 9 of 15 horses died or were euthanatized (fatality rate of 60%).

Animals↗
PubMed1991

Development of surgical techniques for preparation of in vitro-isolated perfused porcine skin flaps for percutaneous absorption studies.

We developed a single-pedicle, axial pattern tubed skin flap that could be transferred to an in vitro perfusion apparatus. On the basis of results of prosections, angiography, contact radiography, and surviving-length studies, it was concluded that a single-pedicle, axial pattern skin flap measuring 4 cm x 12 cm incorporating the caudal superficial epigastric artery would survive to its entire length. Subsequently, a surgical (stage 1) procedure was developed for the routine preparation of single-pedicle, axial pattern tubed skin flaps. Healing after the stage-1 procedure was evaluated by visual inspection and fluorescein angiography. Stage-1 procedures were performed successfully 149 of 160 (93%) times. A second surgical (stage 2) procedure was developed for routine cannulation of the caudal superficial epigastric artery and harvest of the tubed skin flap. Stage-2 procedures were performed successfully 136 of 144 (94%) times.

Animals↗
PubMed1987

Compression bone plating of a medial condylar fracture of the third metatarsal bone in a Thoroughbred filly.

A medial condylar fracture of the third metatarsal bone in a 2-year-old Thoroughbred filly was repaired successfully by use of compression bone plating. At discharge from the hospital, thickening of the metatarsus was evident, and proliferative changes were associated with the site of bone plate application. It was expected that these changes would limit the filly's use as a racehorse, and a return to training was not recommended. Especially in horses that may return to racing, use of compression bone plating initially should not replace stall rest or lag screw fixation treatment of this type of injury. However, the use of a similar approach in selected cases of medial condylar fracture of the third metatarsal bone is encouraged, especially when additional fissure lines are evident on radiographs.

Animals↗