Renal amyloidosis and renal failure--a novel complication of the SAPHO syndrome.
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Biomedical subjects
Publications and source records attributed to K F Gürtler.
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In a patient referred for sclerotherapy of a varicocele, three testicles and focal atrophy in one testicle were additionally diagnosed by ultrasound and MR. In the literature other diseases are occasionally described accompanying this rare benign congenital anomaly.
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A comparison was carried out of the value of plain radiographs, tomography and CT in 37 patients aged between five and 24 years. The majority of these patients had an osteosarcoma. Thirty-five CT examinations were performed on 16 patients and about 300 foci were demonstrated. Plain radiographs only showed 50%, and tomograms only 70% of these lesions. Surgery was carried out in 34 patients and there was agreement between the findings at thoracotomy and radiology in about half the cases. Frequently, more metastases were found at operation than could be demonstrated radiologically, in a few cases there were fewer.
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In a 16-year-old girl who suffered from non-characteristic upper abdominal complaints, the gastrointestinal passage revealed an extreme megaduodenum associated with nonrotation. Intraoperatively, congenital adhesions were found as cause which had stenosed the duodenojejunal transition and had become fixed in the right upper abdomen. After separating the adhesions, resecting the stenosis and narrowing the duodenum, intestinal continuity was restored by means of an end-to side duodenojejunostomy. The causes, signs, diagnosis and therapy of the megaduodenum are discussed.
Among 72 thymic tumors that were examined we have found five (7.5%) thymolipomas. Two of these patients have had clinical symptoms. One, a five-year-old boy, has had an erythrocyte hypoplasia as well as a hypogammaglobulinemia. The other patient, a 56-year-old man, has had myasthenia gravis. This case is the second in the world literature in which a thymolipoma is associated with symptoms of myasthenia gravis. The clinical, radiologic, and histopathologic findings and the pathogenesis of thymolipoma are discussed.
Computed tomography of the mediastinum was performed in 45 patients with myasthenia gravis. Surgery was carried out in fourteen. Amongst these, there were four thymomas, one thymolipoma, eight thymic hyperplasias and one normal thymus gland. A further patient, who did not have surgery, probably also had a thymic tumour. The normal thymus and thymic hyperplasia cannot be distinguished on computed tomography. Differentiation of small thymomas from normal thymus is not always possible. Invasion by thymomas can only be appreciated with large tumours.
The computer tomographic appearances of 16 traumatic lesions of the spleen have been analysed. The changes n the spleen were related to the subsequent therapeutic procedures. The clinically important distinction between parenchymal rupture and parenchymal-capsular rupture can always be made with certainty. CT also adds information concerning parasplenic abnormalities, traumatic changes in upper abdominal organs and additional injuries to other parts of the body.
The computer tomographic findings in 55 patients with histologically confirmed oesophageal carcinomas and in three benign oesophageal tumours are described. In 49 cases, the carcinoma was clearly visible on computer tomography, but in six cases, the tumour was not seen. In another six cases, infiltration into the mediastinum and trachea was demonstrated. In seven patients, regional lymph node metastases were found. The value of computer tomography in oesophageal carcinomas lies in the ability to demonstrate axial spread of the tumour, and the presence of lymphatic or haematogenous metastases during the one examination. This helps in the choice of surgery or in the planning of radiation treatment. Demonstration of the thickness of the oesophageal wall in the region of the tumour can be improved by using a flour-gastrografin paste.
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By the use of a 36 cm image intensifier, its position under the table top and its great focus-image intensifier distance radiation geometric conditions were produced which are identical with the full-size film technique. With this equipment angiographic examinations of the thorax, abdomen as well as extremities were possible with the help of indirect fluorography, In accordance with examinations at anatomical models it turned out that the detail perception of the image intensifier-series fluorography was almost comparable to conventional full size film technique. Aside from the lower radiation dose and the shorter exposure time indirect fluorography offered additional advantages: By means of the fluoroscopic control of the contrast medium and the fluoroscopically controlled exposure a reduction of the methodical procedure was possible with regard to numbers of exposures and series just as saving of time for the complete examination. The evaluation and clinical demonstration of the 100 mm films were critically tested in the daily routine work.