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Biomedical subjects

K F Kessler

Publications and source records attributed to K F Kessler.

4 recordsLinked to original sources
PubMed1983

[Tear film break-up time with different stains].

The tear film break-up time is usually measured with the lacrimal fluid stained with fluorescein. With the staining methods currently recommended the break-up time is difficult to reproduce. In the study described here, the break-up times with different staining methods were compared. The reproducibility of the break-up time was measured shortly after staining and one minute thereafter. The best reproducibility achieved in this study was when the tear fluid was stained with 1 microliter of 5% Na-fluorescein solution.

Adolescent↗
PubMed1982

Physicochemical studies of dinitrophenylated bovine serum albumin.

The structural changes of bovine serum albumin (BSA) as a function of dinitrophenylation have been studied by disc gel electrophoresis, sedimentation velocity analyses, and circular dichroism. These experiments were designed to understand the molecular bases for the change in immunogenicity and antigenicity of BSA upon dinitrophenylation. Dinitrophenylated BSA tends to aggregate to dimers and higher aggregates. A concomitant large change in electrophoretic mobility was also observed. Circular dichroism studies reveal a large decrease in the alpha-helical structure of the BSA molecule.

Animals↗
PubMed1976

[Frequency of obstetrical operations and perinatal mortality before and after admission of continuous fetal monitoring (author's transl)].

Two groups of obstetrical patients were statistically analyzed with a computer. The first group A (2339 deliveries, January 1967-June 1968) was controlled by conservative obstetrical methods, the second group B (2512 deliveries, January 1973-June 1974) was controlled by continuous monitoring of fetal heart rate and by analysis of fetal blood during labour. The results of the statistical analysis can be summarized: 1. The frequency of obstetrical operations (vacuum, obstetrical forceps, Caesarean section) increases from 12.8% (group A) to 22.5% (group B). 2. The percentage of Caesarean sections decided on for the sake of the child rose from 45.7% (group A) to 54.7% (group B). 3. Vital indications fell due to increasingly preventive obstetrics from 54.3% to 45.3%. 4. The frequency of Caesarean sections rose due to increasing indication "absolute or relative pelvic disproportion" of the mediterranean patients. 5. However the analysis of fetal blood during labour and the continuous monitoring of fetal heart rate has prevented a further increase of Caesarean sections. 6. The increasing percentage of obstetric forceps was due to our intention of preventing prolonged labour. 7. Maternal mortality after operative delivery reached 0.04% in group A and 0% in group B. 8. Perinatal mortality of children, delivered by operation, has decreased from 3.0% (group A) to 0,7% (group B). 9. The Apgar scores after operative deliveries were much better in group B (continuous fetal monitoring) than in group A (without fetal monitoring).

Apgar Score↗