PubMed Health⌕ Search

Biomedical subjects

K F Trueman

Publications and source records attributed to K F Trueman.

27 records · Page 2Linked to original sources
PubMed1978

Sodium chloride poisoning in cattle.

Consumption of a sodium chloride based supplement followed by food and water restriction in yards for over 30 hours, resulted in nervous disorders in 5 of 60 three-year-old steers within hours of being released into a paddock. Clinical signs were associated with polioencephalomalacia which was confirmed in 2 of 3 affected steers by microscopic examination of brains. Oedema of the corpus striatum, thalamus and midbrain was observed in 2 animals, and vascular necrosis with neutrophil invasion into the vessel walls was seen in the cerebrum of one steer. Consideration of the history, clinical signs and necropsy findings resulted in a diagnosis of indirect salt poisoning. The affected animals had the lower body weights in the group.

Animals↗
PubMed1978

The effect of age on resistance of cattle to Babesia bovis.

Susceptible Hereford cattle of different ages were inoculated with 2 X 10(8) Babesia bovis organisms. Experiment I consisted of cows aged 6 to 7 years, steers aged 17 to 18 months and calves aged 5 to 6 months, while experiment 2 consisted of cows aged 6.5 to 7.5 years, steers aged 23 to 24 months and yearlings aged 11 to 12 months. Daily measurements of temperature, parasitaemia and packed cell volume were made in order to determine susceptibility of the different ages. Twenty-four of the 36 animals in experiment I, which included all 12 cows, required treatment. One cow died as a result of an enlarged ruptured spleen, and 2 steers and 1 calf died with classical babesiosis symptoms. No treatement was given to experiment II animals, and 5 of the 12 cows died, but the steers and yearlings underwent relatively mild reactions. Statistical analysis confirmed the high susceptibility to B. bovis of the aged cows in both experiments, and the innate resistance of 5 to 6 month old calves in experiment I. The reaction of the 18-month-old steers in experiment I was significantly greater than that of the calves, but significantly less severe than that of the aged cows. Two-year-old steers and yearlings in experiment 2 underwent similar mild reactions, suggesting that innate immunity may persist for longer periods when compared to aged cows. Age groups showing reduced susceptibility were found to reach peak parasitaemia, temperature and anaemia before the more susceptible age groups. Heterologous challenge of the remaining experiment 1 and experiment 2 animals at 6 and 8 months respectively after primary inoculation, revealed all animals of all ages had a solid resistance to B. bovis.

Age Factors↗
PubMed1978

A comparison of 4 serological tests in the detection of humoral antibodies to anaplasmosis in cattle.

A capillary agglutination (CA), a complement fixation (CF), a plate agglutination (PT) and an indirect fluorescent antibody (IFA) test to detect humoral antibodies to Anaplasma marginale are described. Serums from 3, 4 or 5 groups of cattle were used to examine the efficiency of the tests. Agreement between all 4 tests was 86.6%. Agreement between pairs of tests was greater. The CF test was the most sensitive while the PT test was the least sensitive. However the PT could be carried out very rapidly and was suggested as the best screening test, providing improved antigen preparation techniques could increase sensitivity. The CA, CF and IFA tests all showed a stronger homologous antibody reaction when A. marginale antigen was tested against serums obtained from cattle infected with either A. marginale or A. centrale. Antibodies in the A. marginale serums were first detected by day 7 post-inoculation, rose to peak around day 29 and were still present on day 200. Antibodies in the A. centrale serums were first detected by day 29 rose to a peak around day 50 and had disappeared by day 150.

Agglutination Tests↗
PubMed1978

Some effects of reduced energy intake on the development of anaplasmosis in Bos indicus cross steers.

Some effects of the plane of nutrition on the development of anaplasmosis in Brahman cross steers were investigated. Batches of 39 and 30 Brahman cross steers, aged approximately 27 months were each divided by stratified randomisation into 4 groups of similar mean PCV and body weight. Two similar experiments, designated A and B were conducted. Groups 1 and 2 were fed a ration of lucerne chaff at the rate of 1 M Cal ME/80 kg live weight/day for 8 weeks aimed to reduce body weight by approximately 5 kg/week. Animals in groups 3 and 4 were fed a ration for the same period aimed to increase body weight by approximately 2 kg/week. Groups 1 and 3 were then inoculated with approximately 10(10) Anaplasma marginale infected erythrocytes and the effects of the subsequent infections during the clinical and recovery phases were examined by measuring humoral antibody response, packed cell volume, parasitaemia and body weight. Groups 2 and 4 were uninfected controls. Anaplasmosis, as measured by three responses, was less severe in the starved animals of group 1. Significant differences in packed cell volume and parasitaemia were detected for short periods between the infected groups 1 and 3. Anaplasmosis caused losses of 6.2% and 5.9% in the mean body weight of group 3 animals in experiments A and B respectively. Most of this loss occurred during the clinical phase of the disease. The disease caused no apparent loss of weight in the infected animals of group 1.

Anaplasmosis↗
PubMed1977

Gnathostomiasis in three cats.

A fatal infection with Gnathostoma spinigerum causing a perforated stomach is described in a 3-year-old cat. In a second debilitated case a small serosal perforation was found on a gastric lesion, while a third cat in good condition is described with a well developed stomach lesion but without perforation. Histopathological changes in the stomach were found in the submucosa and consisted of marked proliferation of fibrous tissue containing foci of inflammatory cells, necrotic tracts and a cavity in which the adult nematodes were found.

Animals↗
PubMed1976

A study of nephritis of beef cattle in North Queensland.

The incidence of subclinical nephritis in beef cattle slaughtered at a Townsville abattoir during the period 1970-73 was 3.8 percent. A rising incidence coincided with the wet summer of 1973-74 reaching a peak of 8.2 percent thereafter in June 1974. All but 1 of 100 cases macroscopically identified as nephritis and studied histologically proved to be of interstitial type in which lymphocytic infiltration predominated. Follicular lymphoid hyperplasia was also a common feature. The exceptional case showed proliferative glomerulonephritis. Leptospires were isolated from 16 percent of cases cultured, and observed in 8 percent of specimens examined histologically. All of the 8 isolates subjected to serogrouping were L. pomona. Of the animals tested serologically against 2 serotypes 66.2 percent were positive to L. pomona (33.8 percent), L. hardjo (18.9 percent) or both (13.5 percent). The total incidence is significantly higher than in other random surveys carried out in the region. These findings suggest that Leptospira sp. are a major cause of bovine nephritis. Since other pathogens endemic in the area, for example, Babesia and Theileria sp., may be capable of causing nephritis in cattle an accurate assessment of the aetiology of that form of renal disease in north Queensland cannot yet be made.

Agglutinins↗