Biomedical subjects
Publications and source records attributed to K Fagerlund.
Instructional systems design is a process for assessing learning needs, creating instructional programs, and evaluating effectiveness of learning. We discuss the benefits of including instructional systems design theory and practice in the curriculum, with an emphasis on making the process relevant for student nurse anesthetists.
A peptide toxin was isolated from the cyanobacterium Nodularia spumigena by high performance liquid chromatography (HPLC). The i.p. LD50 of the toxin was 50 micrograms/kg mouse with death within 1-3 hr. The major effects of the toxin were seen in the liver in the form of extensive haemorrhages. Amino acid analysis showed the presence of equimolar amounts of glutamic acid, beta-methyl-aspartic acid, and arginine. The toxicological and some of the chemical properties of the isolated toxin were similar to those reported for hepatotoxins isolated from the cyanobacterium Microcystis aeruginosa.