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Biomedical subjects

K Feige

Publications and source records attributed to K Feige.

6 recordsLinked to original sources

[Peritonitis in horses: a retrospective study of 95 cases].

Clinical signs of horses with peritonitis were colic (67.4%), elevated heart rate (53.2%), altered mucous membranes (75.8%), reduced intestinal motility (63.2%), increased tension of the abdominal wall (69.9%) and pyrexia (45.1%). The amount of obtained peritoneal fluid was increased in 62.3% of the horses. Colour and translucency of the peritoneal fluid were abnormal in 98.8% of the patients. The nucleated cell count was 83.5 (10-595) x 10(3)/microliter, protein content 35.6 g/l (+/-14.2), specific gravity 1027.3 (+/-7.4) and the relative amount of neutrophils was 87.8% (+/-11). The physical examination and the examination of the peritoneal fluid were of diagnostic value. Complete blood count and blood chemistry indicated the degree of circulatory depression and the duration of the disease. Overall mortality was 47.4% (45/95). Non-survivors had significantly more often an increased heart- and respiratory rate, altered mucous membranes, an increased tension of the abdominal wall, reduced intestinal motility and increased amount of peritoneal fluid. Packed cell volume, urea, creatinine, glutamatdehydrogenase, sorbitoldehydrogenase, lactatdehydrogenase and blood pH were significantly different between survivors and non-survivors. All these parameters were statistically of no prognostic value.

Animals

[A case of cutaneous epitheliotropic malignant lymphoma (mycosis fungoides) in a horse].

This article describes an eleven year old mare with apathy, fever, enlarged mandibular lymph nodes, skin lesions on the upper lip and edematous, grey-red mucous membranes in the nose, mouth and vulva. Histopathology revealed infiltrates with atypical lymphocytes forming Pautrier's microabscesses. The neoplastic cells had large, often indented nuclei. Immunohistology showed that some cells were CD3-positive (Pan T-cell-marker). The diagnosis of cutaneous epitheliotropic malignant lymphoma (Mycosis fungoides) was made. The etiology in the horse is unknown.

Animals

[Equine motor neuron disease (EMND). A case report].

A 13-year-old warmblood mare was presented because of progressive weight loss, general weakness and trembling. On examination the horse stood with its head lowered and the limbs placed under the body. On lifting its head spasms of the neck muscles could be observed. At the same time the horse developed trembling over the lower neck and muscle fasciculations continued over the whole body. Additional signs included frequent recumbency, polyphagia and facial hyperaesthesia. The horse showed no signs of ataxia. Haematology was normal. Blood biochemistry revealed slight increased aspartate aminotransferase (AST: 1060 U/I) and creatine kinase levels (CK: 441 U/I). Based on the clinical findings equine motor neuron disease was diagnosed. The horse was euthanatized due to poor prognosis and the progression of symptoms. The typical neurodegenerative changes found on histological examination of the spinal cord confirmed the diagnosis.

Animals

[Poisoning of horses by the bark of the false acacia (Robinia pseudoacacia)].

The present study describes the poisoning due to Robinia pseudoacacia in two horses. One of the horses showed mainly intestinal symptoms such as decreased intestinal motility and obstipation of the pelvic flexure. In the second animal central nervous symptoms were predominant. It showed intermittent phases of somnolence alternating with phases of excitation and head pressing. In addition mydriasis and a lacking menace response could be observed. Sensation to the head and the spinal reflexes were reduced. Symptomatic treatment was initiated in both animals and recovery occurred within 2 days.

Animals

[Case report: polycythemia in a horse].

A 13 year old Thoroughbred gelding was presented with a history of a single episode of collapse during mild exercise. Clinical examination revealed a high packed cell volume (PCV) of 72%, a haemoglobin concentration of 24.9 g/l and 15.2 millions erythrocytes/microliters. Despite continuous intravenous infusion therapy with large volumes, the PCV never decreased to a physiological level. The animal showed a normal appetite and no signs of discomfort or syncope. Arterial blood gas values were in the normal range as well as the concentration of erythropoietin (measured by radioimmunoassay, RIA). A test for neoplasms (carcino-embryonic antigen, CEA) was negative. The liver enzymes of the animal were extremely elevated and a liver biopsy showed a severe fibrosis. Examination of sternal bone marrow aspirate revealed no abnormalities. Based on these findings, the presumptive diagnosis was "absolute polycythaemia". The animal was treated for 7 days with repeated phlebotomy. During this time, the PCV never decreased below 50%, despite no obvious signs of discomfort from the animal. Because of the poor prognosis based on the liver biopsy result, the animal was euthanized 11 days after hospitalization. Post mortem findings were: a granular cell myoblastoma with a diameter of approximately 5 cm in the lungs, severe fibrosis of the liver, mild acute tubular nephrosis in the kidneys, activation of the erythropoietic cells in the bone marrow and thrombosis of the abdominal aorta. The possibility of secondary polycythaemia due to the lung neoplasia was not entirely excluded, but considered to be unlikely. Therefore, the definite diagnosis was polycythemia vera.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals