Tetranucleotide repeat polymorphism at the D8S492 locus.
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Biomedical subjects
Publications and source records attributed to K Fillmore.
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Paired urinalysis and urine culture reports on 302 postcesarean patients were studied to determine whether screening postcesarean urinalyses could be useful in predicting positive urine cultures. A positive culture was predicted with a specificity of 97.5% and a sensitivity of 90.4%. The screening urinalysis had a positive predictive value of 73.1% and a negative predictive value of 99.3%. Routine postcesarean urine cultures were not found to be cost effective.
Coagulation profiles (platelet count, prothrombin time, partial thromboplastin time) obtained as part of predelivery screening were examined in patients who presented for delivery with a history of previous cesarean section. Coagulation test results (N = 1439) were reviewed from charts of 482 patients. No change in patient management occurred and no cesarean sections or vaginal deliveries were deferred as a result of the laboratory tests. There were no hemorrhagic complications. No blood products were transfused as a result of the tests. Routine coagulation evaluation is not justified for subsequent delivery of patients who had a previous cesarean section.
Autologous adrenal cortex was completely dissected off the medulla using microdissection. The adrenal medulla tissue was transplanted to the lateral ventricle in twenty-one adult rats. Group A consisting of ten animals received 200 units of HCG per 100 gram body weight daily for one week and then on every alternate day for seven weeks. The remaining rats (group B) served as control. After eight weeks the brains were removed and a volumetric study was done using histological sections. High pressure liquid chromatography (HPLC) with electrochemical detection for catecholamine assay of the graft was also undertaken. The graft survival in group A was significantly higher (p less than 0.005) than group B. The level of norepinephrine was significantly higher in group A while dopamine was higher in group B. The higher volume of graft tissue in group A suggests that HCG may help in increased survival and growth of the transplanted tissue. Higher levels of norepinephrine in group A would suggest a tendency for such grafts to be active to a greater extent with the treatment of HCG.