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Biomedical subjects

K Fuhrmann

Publications and source records attributed to K Fuhrmann.

25 records · Page 2Linked to original sources
PubMed1978

[Value of ultrasonic fetometry for fetal monitoring in diabetes mellitus].

Evaluation of ultrasonic fetometry in diabetic pregnancy. In 51 cases we have carried out 134 ultrasonic investigations. The diabetes we classified to the score of White A--F. To evaluate the increase in fetal weight and the maturity in a qualified sense, we measured the biparietal diameter, the transversal and the sagital diameter of the thorax and the trunk length. The findings were registered into diagrams of our percentiles of development.--The fetopathia diabetica will be diagnosed right, if it is joint with fetal hypertrophy. The beginning of the macrosomia of the fetus is possible to recognize from the 32th week of gestation.

Anthropometry↗
PubMed1977

[Experiences with centralized care for pregnant diabetic women--results of the 1976 treatment period].

73 diabetic pregnant were controled and treated in our clinic 1976, there was a perinatale mortality of 2,7%. The great part of EPH--gestosis and infections of the urinary system and more operative deliveries show of a higher risk already in the stage of latent diabetes. By screening methodes for diabetics during pregnancy and by intensive control in the first trimester it will be possible to obtain better results in the future.

Dexamethasone↗
PubMed1976

[Prevention with antibiotics in cesarean section].

The investigation of 222 patients with caesarean section showed an increasing bacterial invasion of the amniotic fluid, when in the patients preoperative was found: - clear or green colored (meconic) amniotic fluid and intact membranes, - clear amniotic fluid with ruptured membranes and - green-colored (meconic) amniotic fluid and ruptured membranes. In support to some conceptions from the literature a perioperative prophylaxis with antibiotics is recommended in the groups, which are potentially endangered postoperatively.

Anti-Bacterial Agents↗
PubMedDate not supplied

Prevention of congenital malformations in infants of insulin-dependent diabetic mothers.

From April 1977 to April 1981, 420 deliveries of infants of insulin-dependent diabetic women were performed in our department. Of the infants delivered, 23 had congenital malformations (5.5%). The malformation rate was 1.4% for infants of 420 nondiabetic women. Strict metabolic control was begun after 8 wk gestation in 292 of the diabetic women who delivered 22 infants with congenital malformations (7.5%). Intensive treatment was begun before conception in 128 diabetic women planning pregnancy. There was only one malformation in infants of this group (0.8%), a significant reduction from the anomaly rate in the late registrants (X2 = 7.84; P less than 0.01). These observations indicate that reasonable metabolic control started before conception and continued during the first weeks of pregnancy can prevent malformations in infants of diabetic mothers.

Congenital Abnormalities↗
PubMedDate not supplied

Age-dependent insulin secretion of the endocrine pancreas in vitro from fetuses of diabetic and nondiabetic patients.

Fetal hyperinsulinemia is assumed to play a key role in the pathogenesis of diabetic fetopathy. To investigate the role of enhanced fetal B-cell mass as one cause of fetal hyperinsulinemia during diabetic pregnancy, we studied human fetal pancreatic slices from diabetic women (FDW) with poor metabolic control and nondiabetic women (FNDW) between 11 and 26 wk of pregnancy, morphometrically and by in vitro incubation experiments. Abortions had been performed due to different medical indications. We found a good correlation between the calculated B-cell mass and the gestational age in both FDW and FNDW, but the increase in FDW was much more pronounced. Such a correlation was also found in vitro regarding the insulin response to glucose and IBMX. The FDW had significantly higher values than FNDW of the same age range. In contrast to this, we found in two diabetic patients with tight metabolic control during the whole pregnancy results similar to those in FNDW. Therefore, we assume that it could be possible to prevent fetal hyperinsulinemia and perhaps even diabetic fetopathy in diabetic women by tight metabolic control during the whole pregnancy, but further investigations are necessary.

Diabetes Mellitus, Type 1↗