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Biomedical subjects

K Furusawa

Publications and source records attributed to K Furusawa.

83 records · Page 5Linked to original sources
PubMed1983

Synthesis of N-protected deoxynucleosides via 3',5'-cyclic silyl derivatives.

Treatment of deoxynucleosides with dichlorosilanes in pyridine gives 3',5'-cyclic silyl derivatives. Dimethylsilanediyl derivatives and tetramethyldisiloxanediyl derivatives are not stable solvolytically and cleavage of these silyl ethers to the parent deoxynucleosides occurs readily on addition of water. These solvolytically labile bifunctional silyl groups serve as simultaneous transient protecting 3'- and 5'-hydroxyl functions. Acylation and successive hydrolysis of 3',5'-cyclic silyl derivatives gives the corresponding N-protected deoxynucleosides. Some N-acylated deoxy-adenosines and N-anisoyldeoxycytidine were synthesized easily by this N-protection method.

Chemical Phenomena↗
PubMed1975

Virulence of genus Staphylococcus. III. Studies on the pathogenicity to mice.

Six representative strains of staphylococci were selected on the basis of DNase activity and inoculated into the mice to study the correlation of the presence of this enzyme to the virulence of the staphylococci. Two strains of staphylococci among them produced DNase but not the free coagulase, and one of these two strains had an obvious virulence against the mice. The results of experiments suggest that there are at least certain strains which may be designated as Staphylococcus aureus among these DNase-producing staphylococci producing no free coagulase. This is an additional evidence that this enzyme activity should be adopted as a criterion to distinguish from the other S. aureus which has lost the free coagulase activity. In this sense, the staphylococci producing neither free coagulase nor DNase are after all Staphylococcus epidermidis, regardless of their ability to ferment mannitol or not.

Animals↗
PubMedDate not supplied

Appearance of fracture caused by emphysema.

A case presenting radiographic appearance of a fracture line associated with emphysema which occurred in the removal of a mandibular third molar is reported. The cause of the fracture line in the radiograph is discussed together with the benefit of CT in diagnosis.

Dental High-Speed Equipment↗