The immunocompromised patient and transfusion.
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Blood Transfusion↗
Biomedical subjects
K G Badami
Publications and source records attributed to K G Badami.
Coexisting hereditary methaemoglobinaemia and heterozygous beta-thalassaemia.
Cyanosis was noted within a few weeks after birth in two sisters. On investigation the cause of cyanosis was found to be congenital methaemoglobinaemia due to NADH diaphorase deficiency. Heterozygous beta-thalassaemia was present as an additional incidental finding in one of the sisters, but did not contribute to the symptoms, thus showing that the two diseases, when coexistent, do not pose additional haematological problems. However, it is possible that the beta-thalassaemia counteracts the tendency to compensatory erythrocytosis induced by methaemoglobinaemia.
Child, Preschool↗
Disseminated intravascular coagulation in post-dysenteric haemolytic uraemic syndrome.
Coagulation studies were carried out in 14 children with haemolytic uraemic syndrome that followed acute dysentery. Stool cultures showed Shigella dysenteriae in 3 cases and were sterile in the remainder. Prolongation of the prothrombin time, activated partial thromboplastin time and thrombin time and raised levels of fibrinogen degradation products were found in 12 cases, indicating the presence of disseminated intravascular coagulation. Renal histologic examination showed cortical necrosis in 7 cases, which was extensive in 5 and patchy in 2. Disseminated intravascular coagulation may have a role in the pathogenesis of haemolytic uraemic syndrome associated with acute dysentery.
Acute Disease↗
Primary lymphoma of the central nervous system.
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Brain Neoplasms↗