Wegener's granulomatosis.
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Glomerulonephritis↗
Biomedical subjects
K G Chetty
Publications and source records attributed to K G Chetty.
Nucleotide metabolism in the rat liver following whole-body x-irradiation.
Evidence has been presented to show that, like synthesis of RNA, syntheses of ribonucleotide precursors of RNA in the rat liver were stimulated for 6--18 h following whole-body X-irradiation (1000 R).
Animals↗
Suspected superior vena cava syndrome: the role of the Swan-Ganz catheter.
The use of the Swan-Ganz flow-directed catheter in establishing the diagnosis of the superior vena cava syndrome in two patients (one with Hodgkin's disease and the other with carcinoma of the lung) is described. A pressure tracing showing elevated pressure above the obstruction without respiratory or cardiac fluctuations is characteristic of obstruction of the superior vena cava.
Adenocarcinoma↗
Effect of whole-body x-irradiation on rat liver protein synthesis at translational level.
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Animals↗
Mechanisms underlying decreased protein and RNA synthesis in the rat spleen following whole-body X-irradiation.
Whole-body exposure of rats to 1000 R X-rays resulted in decreased rates in protein and RNA syntheses in the spleen from the fourth post-irradiation hour. These changes correspond well with impaired ability of nuclei to polymerise RNA, reduction in template efficiency of chromatin, decrease in the activity of RNA polymerase and inhibition in histone phosphorylation. Protection of the spleen by lead shielding during whole-body exposure to X-rays largely eliminated the observed alterations in protein and nucleic acid synthetic machineries. This suggests that the radiation-induced inhibition in protein and RNA syntheses is mainly due to the direct action of radiation on the spleen itself.
Animals↗