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Biomedical subjects

K G Naik

Publications and source records attributed to K G Naik.

14 recordsLinked to original sources
PubMed1977

Cervical carcinoma in Zambia.

A series of 274 cases of cervical carcinoma in Zambian Africans is presented. Cervical carcinoma formed 29.3% of all female cancers. Poorly differentiated squamous carcinoma constituted the most common histologic type. Concomitant bilharziasis was found in 24.4% of cases. In 59 cases causal factors such as coitus, early marriage, age at first pregnancy and parity were studied and discussed. No correlation was found between circumcision and cervical carcinoma.

Adenocarcinoma↗
PubMed1976

Kala-azar in Zambia: first report of two cases.

Two autochthonous cases of kala-azar, the first such report of the disease from Central and Southern Africa, are described. Both patients presented with generalized macules, papules and nodules without ulceration and both also had tuberculosis. Amastigotes were cultured from blood and identified in skin, bone marrow, liver and spleen.

Aged↗
PubMed1976

Sinus histiocytosis with massive lymphadenopathy.

Five cases of "sinus histiocytosis with massive lymphadenopathy" are reported. The clinical features and histopathological appearances are described. The majority were African children with massive cervical lymphadenopathy. Histologically, the lymphnode sinuses are widely dilated by mature histiocytes, with phagocytosis of lymphocytes and other hematopoietic cells by the proliferating histiocytes. The diagnostic difficulties are discussed. These are the first cases recognized in Zambia.

Adolescent↗
PubMed1975

A case of hartmannellid amebic meningoencephalitis in Zambia.

A case of amebic meningoencephalitis recognized in an adult Zambian is described. This is the first authenticated case from Africa. The morphologic features of the organism, its ability to form cysts in tissue, and the granulomatous tissue response denote that the ameba is an hartmannellid rather than a Naegleria. Free-living amebas of the family Hartmannellidae have not been incriminated before as a cause of primary amebic meningoencephalitis in man. To our knowledge this is the only case where such an ameba was responsible for fulminating meningoencephalitis. The presence of the amebas in a cellulocutaneous abdominal lesion suggests hematogenous dissemination.

Amebiasis↗
PubMedDate not supplied

Primary carcinoma of the liver in Zambia.

A review of liver biopsies over a three year period revealed 166 cases of carcinoma of the liver. Hepatocellular carcinoma constituted the commonest malignant tumour in male Zambians. The different histologic sub-types were studied and compared wth a study of liver cell cancer in Uganda. Trabecular carcinoma was the commonest histological type. A significant association of hepatocellular carcinoma with macronodular cirrhosis was noted.

Adenocarcinoma↗
PubMedDate not supplied

A review of autopsies at the University Teaching Hospital, Lusaka, 1975.

Findings in all clinical autopsies performed in 1975 are presented. The autopsy rate for all deaths was 17%, it was only 10% in childhood deaths, but rose to nearly 34% if stillbirths and neonatal deaths are excluded. The main causes of death are classified in major fields. In adults neoplasms were the commonest cause of death with acute infections and cardiac diseases following in order of importance. The value of the clinical autopsy is briefly discussed.

Adolescent↗
PubMedDate not supplied

Pattern of tumors of the male genitalia in Zambia.

Tumors of the prostate, penis and testis respectively formed 3.5% and 0.5% of all male cancers. These findings are compared with those of various studies and some possible etiologic factors are discussed.

Adult↗