PubMed HealthSearch

Biomedical subjects

K G Rao

Publications and source records attributed to K G Rao.

At least 19 recordsLinked to original sources

Real-time renal sonography in spinal cord injury patients: prospective comparison with excretory urography.

A prospective blinded comparison of real-time renal sonography and excretory urography was done in 202 urologically asymptomatic patients with spinal cord injury who underwent periodic evaluation. Sonography identified 31 of 31 renal masses (100 per cent) (30 cysts and 1 xanthogranulomatous pyelonephritis), whereas excretory urography identified 14 of 31 masses (45 per cent). Of the 398 kidneys evaluated hydronephrosis owing to an obstructive etiology was noted in 7, all of which (100 per cent) were identified on excretory urography and 6 (86 per cent) were identified on sonography. Only 12 of the 48 kidneys (25 per cent) with typical changes of chronic pyelonephritis on excretory urography were diagnosed correctly by ultrasound. Sonography identified 18 of 23 kidneys (78 per cent) with calculi compared to 20 of 23 (87 per cent) by excretory urography. Although 127 abnormalities were noted in 202 patients, only 21 dictated a change in management. Thirteen abnormalities were visible on a plain film of the kidneys, ureters and bladder (3 kidneys with stones, 1 ureteral stone and 9 bladders with stones). We conclude that sonography and excretory urography are excellent diagnostic modalities for the evaluation of the kidneys. Sonography, plain radiograph of the abdomen and post-contrast injection x-rays on excretory urography frequently offer complementary diagnostic information. The noninvasive nature of ultrasound examination and lack of x-ray exposure combined with no need for special patient preparation make ultrasound examination extremely attractive in this patient population. It is recommended that real-time renal ultrasound and a plain radiograph of the abdomen be used on an alternate basis with excretory urography for the routine followup of spinal cord injury patients.

Adult

Diverticulosis of the appendix: radiographic and clinical features.

We have reported three cases of appendiceal diverticulosis diagnosed by barium enema examination, and reviewed the radiographic and clinical findings. An awareness of this lesion is important, since diverticulitis of the appendix may occur in up to two thirds of patients with DA.

Appendix

Scapular fracture.

Explore the source record for details and available documents.

Fractures, Bone

Carcinoma of prostate presenting as intracranial tumor with multiple cranial nerve palsies.

Carcinoma of the prostate is one of the commonest of cancers occurring in men over the age of fifty years. A small focus of cancer in the prostate can be active biologically and give rise to metastases without producing any symptoms of bladder neck obstruction. In such cases, the attention may be directed away from the prostate. A review of literature reveals that practically no organ in the body is exempt from metastasis from a carcinoma of the prostate. A routine rectal examination and if necessary a biopsy of the prostate should not be omitted in any patient beyond the age of fifty years. A case of carcinoma of prostate presenting as an intracranial tumor causing multiple cranial nerve palsies is presented. This is the first report of such a case.

Adenocarcinoma

Pyrrolines as prodrugs of gamma-aminobutyric acid analogues.

delta 1-Pyrroline, 5-methyl-delta 1-pyrroline, and 5,5-dimethyl-delta 1-pyrroline have been identified as substances metabolized to gamma-aminobutyric acid (GABA), 4-aminopentanoic acid (methylGABA), and 4-amino-4-methylpentanoic acid (dimethylGABA), respectively. An enzyme system residing in the soluble fraction of rabbit liver catalyzes the conversion of delta 1-pyrroline to GABA and its lactam, 2-pyrrolidinone. Acetaldehyde, allopurinol, and cyanide inhibited the reaction. Incubation of deuterium-labeled delta 1-pyrroline with mouse brain homogenates produced deuterated GABA. Mouse liver 10,000 g supernatant and mouse brain homogenates converted 5-methyl-delta 1-pyrroline to methylGABA, and 5,5-dimethyl-delta 1-pyrroline to dimethylGABA. Four hours after intraperitoneal injection of 5-methyl-delta 1-pyrroline (200 mg/kg), methylGABA was detected in mouse brain (0.27 mumol/g). DimethylGABA (1.21 mumol/g) was determined in mouse brain 30 min after intraperitoneal administration of 5,5-dimethyl-delta 1-pyrroline (200 mg/kg). Neither methylGABA nor dimethylGABA penetrated into the central nervous system when administered in the periphery. The present studies suggest that pyrrolines may represent a chemical class of brain-penetrating precursors of pharmacologically active analogues of GABA.

Animals

Excessive right subdiaphragmatic fat: a potential diagnostic pitfall.

Excessive rat in the right subdiaphragmatic region may simulate pathological processes such as subdiaphragmatic abscess, subpulmonic pleural effusion, ascites, tumor, and pneumoperitoneum. This report describes six patients with excessive subdiaphragmatic fat who were examined with plain radiography (all six patients), computed tomography (CT) (three patients), and ultrasound (two patients). Plain radiographs demonstrated an appreciable radiolucency separating the liver and right hemidiaphragm in all cases. It is concluded that CT is the best imaging modality for diagnosing this condition, but it may be recognized confidently on ultrasonographic scans and plain radiographs.

Adipose Tissue

Noninvasive assessment of the transplanted kidney: ultrasound vs. computerized tomography.

In our experience both ultrasound and CT are highly diagnostic in the identification of the posttransplant fluid collections and hydronephrosis. As is the case elsewhere in the abdomen, the two examinations appear to be complementary. Ultrasound should be the initial diagnostic modality due to the advantages mentioned before; CT is helpful in resolving questionable abnormalities noted on ultrasound or in difficult clinical situations. Combination of the two examinations in selected cases improves sensitivity and specificity in the detection of postoperative complications.

Kidney Transplantation

Plasmacytoma of the large bowel: a review of the literature and a case report of multiple myeloma involving the rectosigmoid.

Large bowel involvement is a rare manifestation of plasma cell tumors, especially in association with multiple myeloma. A review of the world literature reveals only 21 reported cases, the majority of which are classified as the solitary form of the disease. A case of multiple myeloma with rectosigmoid involvement is herein presented, and the radiological findings of reported cases are summarized.

Colon, Sigmoid

Significance of unilateral diminished activity in renal scanning.

Renal scanning is an important diagnostic aid in assessing kidney function; the authors have attempted to correlate the results of renal scanning with the findings from intravenous pyelography and the final diagnosis. In non-mass lesions of the kidney the renal scan correlated well with the intravenous pyelogram and the final diagnosis. In mass lesions, a diminished uptake of isotope corresponding to the site of the lesion seen on the intravenous pyelogram was suggestive of a cyst; diminished uptake of isotope in the whole kidney including the mass lesion on the renal scan was suggestive of renal carcinoma. Review of the literature showed only one previous reference to such an observation.

Adult

Congenital proximal bulbar stricture in adults.

Congenital proximal bulbar stricture in adults is a definite clinical entity and should be looked for in adults with obscure urinary symptoms. The stricture is usually short and can be demonstrated with a voiding cystogram, urethrogram, and urethroscopy. The condition is thought to be due to incomplete rupture of the cloacal membrane at its junction with the urogenital sinus. The stricture can be treated easily by internal urethrotomy and/or urethral dilatation.

Adolescent